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8  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MALT1_HUMAN (Q9UDY8)

Summary

This is the summary of UniProt entry MALT1_HUMAN (Q9UDY8).

Description: Mucosa-associated lymphoid tissue lymphoma translocation protein 1 EC=3.4.22.-
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 824 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 6 10
low_complexity n/a 9 29
disorder n/a 13 26
low_complexity n/a 29 44
Pfam Ig_3 124 194
Pfam Ig_2 226 308
disorder n/a 318 336
Pfam Peptidase_C14 343 560
low_complexity n/a 398 411
Pfam MALT1_Ig 583 719
disorder n/a 643 646
disorder n/a 650 655
disorder n/a 743 745
disorder n/a 761 765
disorder n/a 772 774
low_complexity n/a 784 800

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UDY8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSLLGDPLQA LPPSAAPTGP LLAPPAGATL NRLREPLLRR LSELLDQAPE
50
51
GRGWRRLAEL AGSRGRLRLS CLDLEQCSLK VLEPEGSPSL CLLKLMGEKG
100
101
CTVTELSDFL QAMEHTEVLQ LLSPPGIKIT VNPESKAVLA GQFVKLCCRA
150
151
TGHPFVQYQW FKMNKEIPNG NTSELIFNAV HVKDAGFYVC RVNNNFTFEF
200
201
SQWSQLDVCD IPESFQRSVD GVSESKLQIC VEPTSQKLMP GSTLVLQCVA
250
251
VGSPIPHYQW FKNELPLTHE TKKLYMVPYV DLEHQGTYWC HVYNDRDSQD
300
301
SKKVEIIIGR TDEAVECTED ELNNLGHPDN KEQTTDQPLA KDKVALLIGN
350
351
MNYREHPKLK APLVDVYELT NLLRQLDFKV VSLLDLTEYE MRNAVDEFLL
400
401
LLDKGVYGLL YYAGHGYENF GNSFMVPVDA PNPYRSENCL CVQNILKLMQ
450
451
EKETGLNVFL LDMCRKRNDY DDTIPILDAL KVTANIVFGY ATCQGAEAFE
500
501
IQHSGLANGI FMKFLKDRLL EDKKITVLLD EVAEDMGKCH LTKGKQALEI
550
551
RSSLSEKRAL TDPIQGTEYS AESLVRNLQW AKAHELPESM CLKFDCGVQI
600
601
QLGFAAEFSN VMIIYTSIVY KPPEIIMCDA YVTDFPLDLD IDPKDANKGT
650
651
PEETGSYLVS KDLPKHCLYT RLSSLQKLKE HLVFTVCLSY QYSGLEDTVE
700
701
DKQEVNVGKP LIAKLDMHRG LGRKTCFQTC LMSNGPYQSS AATSGGAGHY
750
751
HSLQDPFHGV YHSHPGNPSN VTPADSCHCS RTPDAFISSF AHHASCHFSR
800
801
SNVPVETTDE IPFSFSDRLR ISEK                            
824
 

Show the unformatted sequence.

Checksums:
CRC64:28AFB80DA025F8AB
MD5:108c06516aadc9436be7a27d382a5320

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ig_2 226 - 308 3BFO A 226 - 308 Jmol OpenAstexViewer
B 226 - 308 Jmol OpenAstexViewer
C 226 - 308 Jmol OpenAstexViewer
D 226 - 308 Jmol OpenAstexViewer
3K0W A 226 - 308 Jmol OpenAstexViewer
Ig_3 128 - 194 3K0W A 128 - 194 Jmol OpenAstexViewer
MALT1_Ig 583 - 715 3UO8 B 583 - 715 Jmol OpenAstexViewer
3UOA B 583 - 715 Jmol OpenAstexViewer
583 - 716 4I1P A 583 - 716 Jmol OpenAstexViewer
583 - 717 4I1P C 583 - 717 Jmol OpenAstexViewer
583 - 718 3UO8 C 583 - 718 Jmol OpenAstexViewer
3UOA C 583 - 718 Jmol OpenAstexViewer
583 - 719 3V55 A 583 - 719 Jmol OpenAstexViewer
4I1R A 583 - 719 Jmol OpenAstexViewer
Peptidase_C14 343 - 560 3UO8 B 343 - 560 Jmol OpenAstexViewer
C 343 - 560 Jmol OpenAstexViewer
3UOA B 343 - 560 Jmol OpenAstexViewer
C 343 - 560 Jmol OpenAstexViewer
3V4O A 343 - 560 Jmol OpenAstexViewer
3V55 A 343 - 560 Jmol OpenAstexViewer
4I1P A 343 - 560 Jmol OpenAstexViewer
C 343 - 560 Jmol OpenAstexViewer
4I1R A 343 - 560 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.