Summary
This is the summary of UniProt entry DACH1_HUMAN (Q9UI36).
| Description: | Dachshund homolog 1 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
| Length: | 758 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 188 |
| low_complexity | n/a | 6 | 19 |
| low_complexity | n/a | 17 | 52 |
| low_complexity | n/a | 60 | 67 |
| low_complexity | n/a | 73 | 102 |
| low_complexity | n/a | 108 | 130 |
| low_complexity | n/a | 139 | 162 |
| Pfam | Ski_Sno | 172 | 281 |
| disorder | n/a | 278 | 313 |
| disorder | n/a | 315 | 317 |
| disorder | n/a | 324 | 325 |
| low_complexity | n/a | 324 | 340 |
| disorder | n/a | 350 | 433 |
| disorder | n/a | 435 | 438 |
| disorder | n/a | 440 | 610 |
| low_complexity | n/a | 501 | 528 |
| low_complexity | n/a | 597 | 616 |
| coiled_coil | n/a | 633 | 658 |
| disorder | n/a | 640 | 649 |
| low_complexity | n/a | 654 | 664 |
| coiled_coil | n/a | 661 | 716 |
| disorder | n/a | 663 | 668 |
| disorder | n/a | 675 | 676 |
| low_complexity | n/a | 678 | 696 |
| disorder | n/a | 679 | 680 |
| disorder | n/a | 693 | 701 |
| disorder | n/a | 703 | 714 |
| disorder | n/a | 717 | 718 |
| disorder | n/a | 721 | 746 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UI36. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MAVPAALIPP TQLVPPQPPI STSASSSGTT TSTSSATSSP APSIGPPASS
50 51
GPTLFRPEPI ASAAAAAATV TSTGGGGGGG GSGGGGGSSG NGGGGGGGGG
100 101
GSNCNPNLAA ASNGSGGGGG GISAGGGVAS STPINASTGS SSSSSSSSSS
150 151
SSSSSSSSSS SSSCGPLPGK PVYSTPSPVE NTPQNNECKM VDLRGAKVAS
200 201
FTVEGCELIC LPQAFDLFLK HLVGGLHTVY TKLKRLEITP VVCNVEQVRI
250 251
LRGLGAIQPG VNRCKLISRK DFETLYNDCT NASSRPGRPP KRTQSVTSPE
300 301
NSHIMPHSVP GLMSPGIIPP TGLTAAAAAA AAATNAAIAE AMKVKKIKLE
350 351
AMSNYHASNN QHGADSENGD MNSSVGSSDG SWDKETLPSS PSQGPQASIT
400 401
HPRMPGARSL PLSHPLNHLQ QSHLLPNGLE LPFMMMPHPL IPVSLPPASV
450 451
TMAMSQMNHL STIANMAAAA QVQSPPSRVE TSVIKERVPD SPSPAPSLEE
500 501
GRRPGSHPSS HRSSSVSSSP ARTESSSDRI PVHQNGLSMN QMLMGLSPNV
550 551
LPGPKEGDLA GHDMGHESKR MHIEKDETPL STPTARDSLD KLSLTGHGQP
600 601
LPPGFPSPFL FPDGLSSIET LLTNIQGLLK VAIDNARAQE KQVQLEKTEL
650 651
KMDFLREREL RETLEKQLAM EQKNRAIVQK RLKKEKKAKR KLQEALEFET
700 701
KRREQAEQTL KQAASTDSLR VLNDSLTPEI EADRSGGRTD AERTIQDGRL
750 751
YLKTTVMY
758
Show the unformatted sequence. |
| Checksums: |
CRC64:DFB5054D7EC5FF11
MD5:1933bc7caaf577ed01802eb0d7a7a8a0
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| Ski_Sno | 184 - 281 | 1L8R | A | 184 - 281 | Jmol OpenAstexViewer |
| B | 184 - 281 | Jmol OpenAstexViewer |
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
