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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: DACH1_HUMAN (Q9UI36)

Summary

This is the summary of UniProt entry DACH1_HUMAN (Q9UI36).

Description: Dachshund homolog 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 758 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 188
low_complexity n/a 6 19
low_complexity n/a 17 52
low_complexity n/a 60 67
low_complexity n/a 73 102
low_complexity n/a 108 130
low_complexity n/a 139 162
Pfam Ski_Sno 172 281
disorder n/a 278 313
disorder n/a 315 317
disorder n/a 324 325
low_complexity n/a 324 340
disorder n/a 350 433
disorder n/a 435 438
disorder n/a 440 610
low_complexity n/a 501 528
low_complexity n/a 597 616
coiled_coil n/a 633 658
disorder n/a 640 649
low_complexity n/a 654 664
coiled_coil n/a 661 716
disorder n/a 663 668
disorder n/a 675 676
low_complexity n/a 678 696
disorder n/a 679 680
disorder n/a 693 701
disorder n/a 703 714
disorder n/a 717 718
disorder n/a 721 746

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UI36. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAVPAALIPP TQLVPPQPPI STSASSSGTT TSTSSATSSP APSIGPPASS
50
51
GPTLFRPEPI ASAAAAAATV TSTGGGGGGG GSGGGGGSSG NGGGGGGGGG
100
101
GSNCNPNLAA ASNGSGGGGG GISAGGGVAS STPINASTGS SSSSSSSSSS
150
151
SSSSSSSSSS SSSCGPLPGK PVYSTPSPVE NTPQNNECKM VDLRGAKVAS
200
201
FTVEGCELIC LPQAFDLFLK HLVGGLHTVY TKLKRLEITP VVCNVEQVRI
250
251
LRGLGAIQPG VNRCKLISRK DFETLYNDCT NASSRPGRPP KRTQSVTSPE
300
301
NSHIMPHSVP GLMSPGIIPP TGLTAAAAAA AAATNAAIAE AMKVKKIKLE
350
351
AMSNYHASNN QHGADSENGD MNSSVGSSDG SWDKETLPSS PSQGPQASIT
400
401
HPRMPGARSL PLSHPLNHLQ QSHLLPNGLE LPFMMMPHPL IPVSLPPASV
450
451
TMAMSQMNHL STIANMAAAA QVQSPPSRVE TSVIKERVPD SPSPAPSLEE
500
501
GRRPGSHPSS HRSSSVSSSP ARTESSSDRI PVHQNGLSMN QMLMGLSPNV
550
551
LPGPKEGDLA GHDMGHESKR MHIEKDETPL STPTARDSLD KLSLTGHGQP
600
601
LPPGFPSPFL FPDGLSSIET LLTNIQGLLK VAIDNARAQE KQVQLEKTEL
650
651
KMDFLREREL RETLEKQLAM EQKNRAIVQK RLKKEKKAKR KLQEALEFET
700
701
KRREQAEQTL KQAASTDSLR VLNDSLTPEI EADRSGGRTD AERTIQDGRL
750
751
YLKTTVMY                                              
758
 

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Checksums:
CRC64:DFB5054D7EC5FF11
MD5:1933bc7caaf577ed01802eb0d7a7a8a0

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ski_Sno 184 - 281 1L8R A 184 - 281 Jmol OpenAstexViewer
B 184 - 281 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.