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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: FBX4_HUMAN (Q9UKT5)

Summary

This is the summary of UniProt entry FBX4_HUMAN (Q9UKT5).

Description: F-box only protein 4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 387 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 15
disorder n/a 46 47
disorder n/a 49 50
Pfam F-box 57 104
low_complexity n/a 191 202
disorder n/a 245 263
disorder n/a 266 267
disorder n/a 270 271
low_complexity n/a 347 354

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UKT5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAGSEPRSGT NSPPPPFSDW GRLEAAILSG WKTFWQSVSK ERVARTTSRE
50
51
EVDEAASTLT RLPIDVQLYI LSFLSPHDLC QLGSTNHYWN ETVRDPILWR
100
101
YFLLRDLPSW SSVDWKSLPD LEILKKPISE VTDGAFFDYM AVYRMCCPYT
150
151
RRASKSSRPM YGAVTSFLHS LIIQNEPRFA MFGPGLEELN TSLVLSLMSS
200
201
EELCPTAGLP QRQIDGIGSG VNFQLNNQHK FNILILYSTT RKERDRAREE
250
251
HTSAVNKMFS RHNEGDDQQG SRYSVIPQIQ KVCEVVDGFI YVANAEAHKR
300
301
HEWQDEFSHI MAMTDPAFGS SGRPLLVLSC ISQGDVKRMP CFYLAHELHL
350
351
NLLNHPWLVQ DTEAETLTGF LNGIEWILEE VESKRAR              
387
 

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Checksums:
CRC64:BD5E8DD14B9733E9
MD5:0e95af526d4b5de85d8c36e8fedb36cb

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
F-box 57 - 104 3L2O B 57 - 104 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.