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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: FBXL3_HUMAN (Q9UKT7)

Summary

This is the summary of UniProt entry FBXL3_HUMAN (Q9UKT7).

Description: F-box/LRR-repeat protein 3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 428 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 27
Pfam F-box-like 41 81
low_complexity n/a 234 246

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UKT7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKRGGRDSDR NSSEEGTAEK SKKLRTTNEH SQTCDWGNLL QDIILQVFKY
50
51
LPLLDRAHAS QVCRNWNQVF HMPDLWRCFE FELNQPATSY LKATHPELIK
100
101
QIIKRHSNHL QYVSFKVDSS KESAEAACDI LSQLVNCSLK TLGLISTARP
150
151
SFMDLPKSHF ISALTVVFVN SKSLSSLKID DTPVDDPSLK VLVANNSDTL
200
201
KLLKMSSCPH VSPAGILCVA DQCHGLRELA LNYHLLSDEL LLALSSEKHV
250
251
RLEHLRIDVV SENPGQTHFH TIQKSSWDAF IRHSPKVNLV MYFFLYEEEF
300
301
DPFFRYEIPA THLYFGRSVS KDVLGRVGMT CPRLVELVVC ANGLRPLDEE
350
351
LIRIAERCKN LSAIGLGECE VSCSAFVEFV KMCGGRLSQL SIMEEVLIPD
400
401
QKYSLEQIHW EVSKHLGRVW FPDMMPTW                        
428
 

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Checksums:
CRC64:AAEAB31BAF0EA5A5
MD5:8600e9e34c09610241bb4eafe1d3de17

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
F-box-like 41 - 81 4I6J B 41 - 81 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.