Summary
This is the summary of UniProt entry TRPC5_HUMAN (Q9UL62).
Description: | Short transient receptor potential channel 5 |
Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
Length: | 973 amino acids |
Reference Proteome: |
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Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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Source | Domain | Start | End |
---|---|---|---|
Pfam | Ank_2 | 36 | 129 |
low_complexity | n/a | 73 | 91 |
Pfam | TRP_2 | 176 | 238 |
low_complexity | n/a | 178 | 187 |
low_complexity | n/a | 202 | 213 |
coiled_coil | n/a | 227 | 247 |
transmembrane | n/a | 327 | 351 |
Pfam | Ion_trans | 363 | 636 |
transmembrane | n/a | 363 | 382 |
transmembrane | n/a | 402 | 419 |
transmembrane | n/a | 440 | 460 |
transmembrane | n/a | 480 | 499 |
low_complexity | n/a | 484 | 496 |
transmembrane | n/a | 520 | 542 |
transmembrane | n/a | 571 | 587 |
transmembrane | n/a | 599 | 621 |
low_complexity | n/a | 685 | 702 |
disorder | n/a | 687 | 696 |
disorder | n/a | 737 | 741 |
disorder | n/a | 768 | 793 |
disorder | n/a | 810 | 835 |
low_complexity | n/a | 841 | 852 |
disorder | n/a | 859 | 864 |
disorder | n/a | 905 | 906 |
low_complexity | n/a | 918 | 943 |
disorder | n/a | 968 | 973 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UL62. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
Sequence: | 1
MAQLYYKKVN YSPYRDRIPL QIVRAETELS AEEKAFLNAV EKGDYATVKQ
50 51
ALQEAEIYYN VNINCMDPLG RSALLIAIEN ENLEIMELLL NHSVYVGDAL
100 101
LYAIRKEVVG AVELLLSYRR PSGEKQVPTL MMDTQFSEFT PDITPIMLAA
150 151
HTNNYEIIKL LVQKRVTIPR PHQIRCNCVE CVSSSEVDSL RHSRSRLNIY
200 201
KALASPSLIA LSSEDPILTA FRLGWELKEL SKVENEFKAE YEELSQQCKL
250 251
FAKDLLDQAR SSRELEIILN HRDDHSEELD PQKYHDLAKL KVAIKYHQKE
300 301
FVAQPNCQQL LATLWYDGFP GWRRKHWVVK LLTCMTIGFL FPMLSIAYLI
350 351
SPRSNLGLFI KKPFIKFICH TASYLTFLFM LLLASQHIVR TDLHVQGPPP
400 401
TVVEWMILPW VLGFIWGEIK EMWDGGFTEY IHDWWNLMDF AMNSLYLATI
450 451
SLKIVAYVKY NGSRPREEWE MWHPTLIAEA LFAISNILSS LRLISLFTAN
500 501
SHLGPLQISL GRMLLDILKF LFIYCLVLLA FANGLNQLYF YYETRAIDEP
550 551
NNCKGIRCEK QNNAFSTLFE TLQSLFWSVF GLLNLYVTNV KARHEFTEFV
600 601
GATMFGTYNV ISLVVLLNML IAMMNNSYQL IADHADIEWK FARTKLWMSY
650 651
FDEGGTLPPP FNIIPSPKSF LYLGNWFNNT FCPKRDPDGR RRRRNLRSFT
700 701
ERNADSLIQN QHYQEVIRNL VKRYVAAMIR NSKTHEGLTE ENFKELKQDI
750 751
SSFRYEVLDL LGNRKHPRSF STSSTELSQR DDNNDGSGGA RAKSKSVSFN
800 801
LGCKKKTCHG PPLIRTMPRS SGAQGKSKAE SSSKRSFMGP SLKKLGLLFS
850 851
KFNGHMSEPS SEPMYTISDG IVQQHCMWQD IRYSQMEKGK AEACSQSEIN
900 901
LSEVELGEVQ GAAQSSECPL ACSSSLHCAS SICSSNSKLL DSSEDVFETW
950 951
GEACDLLMHK WGDGQEEQVT TRL
973
Show the unformatted sequence. |
Checksums: |
CRC64:FBC8CBF17BE42166
MD5:bb10ae6c351d27c749c0ac9fbe1c3f60
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
The parts of the structure corresponding to the Pfam family are highlighted in blue.
Loading Structure Data
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
Very High (pLDDT > 90) | |
Confident (90 > pLDDT > 70) | |
Low (70 > pLDDT > 50) | |
Very Low (pLDDT < 50) |