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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: BRPF3_HUMAN (Q9ULD4)

Summary

This is the summary of UniProt entry BRPF3_HUMAN (Q9ULD4).

Description: Bromodomain and PHD finger-containing protein 3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1205 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 29
disorder n/a 36 40
Pfam EPL1 48 194
disorder n/a 66 110
low_complexity n/a 88 104
disorder n/a 116 126
disorder n/a 135 138
disorder n/a 148 154
Pfam PHD_2 226 260
Pfam zf-HC5HC2H_2 267 386
disorder n/a 388 476
low_complexity n/a 405 435
low_complexity n/a 445 457
disorder n/a 520 540
low_complexity n/a 558 577
coiled_coil n/a 565 592
Pfam Bromodomain 598 681
disorder n/a 700 708
disorder n/a 742 743
low_complexity n/a 763 772
disorder n/a 765 766
disorder n/a 768 770
disorder n/a 774 1015
low_complexity n/a 783 790
low_complexity n/a 831 844
low_complexity n/a 842 856
low_complexity n/a 966 988
disorder n/a 1027 1050
disorder n/a 1052 1053
Pfam PWWP 1074 1191

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9ULD4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRKPRRKSRQ NAEGRRSPSP YSLKCSPTRE TLTYAQAQRI VEVDIDGRLH
50
51
RISIYDPLKI ITEDELTAQD ITECNSNKEN SEQPQFPGKS KKPSSKGKKK
100
101
ESCSKHASGT SFHLPQPSFR MVDSGIQPEA PPLPAAYYRY IEKPPEDLDA
150
151
EVEYDMDEED LAWLDMVNEK RRVDGHSLVS ADTFELLVDR LEKESYLESR
200
201
SSGAQQSLID EDAFCCVCLD DECHNSNVIL FCDICNLAVH QECYGVPYIP
250
251
EGQWLCRCCL QSPSRPVDCI LCPNKGGAFK QTSDGHWAHV VCAIWIPEVC
300
301
FANTVFLEPI EGIDNIPPAR WKLTCYICKQ KGLGAAIQCH KVNCYTAFHV
350
351
TCAQRAGLFM KIEPMRETSL NGTIFTVRKT AYCEAHSPPG AATARRKGDS
400
401
PRSISETGDE EGLKEGDGEE EEEEEVEEEE QEAQGGVSGS LKGVPKKSKM
450
451
SLKQKIKKEP EEAGQDTPST LPMLAVPQIP SYRLNKICSG LSFQRKNQFM
500
501
QRLHNYWLLK RQARNGVPLI RRLHSHLQSQ RNAEQREQDE KTSAVKEELK
550
551
YWQKLRHDLE RARLLIELIR KREKLKREQV KVQQAAMELE LMPFNVLLRT
600
601
TLDLLQEKDP AHIFAEPVNL SEVPDYLEFI SKPMDFSTMR RKLESHLYRT
650
651
LEEFEEDFNL IVTNCMKYNA KDTIFHRAAV RLRDLGGAIL RHARRQAENI
700
701
GYDPERGTHL PESPKLEDFY RFSWEDVDNI LIPENRAHLS PEVQLKELLE
750
751
KLDLVSAMRS SGARTRRVRL LRREINALRQ KLAQPPPPQP PSLNKTVSNG
800
801
ELPAGPQGDA AVLEQALQEE PEDDGDRDDS KLPPPPTLEP TGPAPSLSEQ
850
851
ESPPEPPTLK PINDSKPPSR FLKPRKVEED ELLEKSPLQL GNEPLQRLLS
900
901
DNGINRLSLM APDTPAGTPL SGVGRRTSVL FKKAKNGVKL QRSPDRVLEN
950
951
GEDHGVAGSP ASPASIEEER HSRKRPRSRS CSESEGERSP QQEEETGMTN
1000
1001
GFGKHTESGS DSECSLGLSG GLAFEACSGL TPPKRSRGKP ALSRVPFLEG
1050
1051
VNGDSDYNGS GRSLLLPFED RGDLEPLELV WAKCRGYPSY PALIIDPKMP
1100
1101
REGLLHNGVP IPVPPLDVLK LGEQKQAEAG EKLFLVLFFD NKRTWQWLPR
1150
1151
DKVLPLGVED TVDKLKMLEG RKTSIRKSVQ VAYDRAMIHL SRVRGPHSFV
1200
1201
TSSYL                                                 
1205
 

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Checksums:
CRC64:F51DCAB253ED35C7
MD5:e0fca7300889f1416f8c1341f759fdd1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PWWP 1074 - 1191 3PFS A 1074 - 1191 Jmol OpenAstexViewer
B 1074 - 1191 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.