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15  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: APC10_HUMAN (Q9UM13)

Summary

This is the summary of UniProt entry APC10_HUMAN (Q9UM13).

Description: Anaphase-promoting complex subunit 10
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 185 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 20
Pfam ANAPC10 4 183
disorder n/a 153 155

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UM13. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTTPNKTPPG ADPKQLERTG TVREIGSQAV WSLSSCKPGF GVDQLRDDNL
50
51
ETYWQSDGSQ PHLVNIQFRR KTTVKTLCIY ADYKSDESYT PSKISVRVGN
100
101
NFHNLQEIRQ LELVEPSGWI HVPLTDNHKK PTRTFMIQIA VLANHQNGRD
150
151
THMRQIKIYT PVEESSIGKF PRCTTIDFMM YRSIR                
185
 

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Checksums:
CRC64:ACA7F245B3861FF5
MD5:e31de5bd9b36d5495c346b11a083f868

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ANAPC10 11 - 183 5KHR L 11 - 182 Show 3D Structure View in InterPro
5KHU L 11 - 182 Show 3D Structure View in InterPro
5L9T L 11 - 182 Show 3D Structure View in InterPro
4 - 162 1JHJ A 4 - 162 Show 3D Structure View in InterPro
4 - 183 4UI9 L 4 - 182 Show 3D Structure View in InterPro
5A31 L 4 - 182 Show 3D Structure View in InterPro
5G04 L 4 - 182 Show 3D Structure View in InterPro
5G05 L 4 - 182 Show 3D Structure View in InterPro
5L9U L 4 - 182 Show 3D Structure View in InterPro
5LCW L 4 - 182 Show 3D Structure View in InterPro
6Q6G L 4 - 183 Show 3D Structure View in InterPro
6Q6H L 4 - 183 Show 3D Structure View in InterPro
6TLJ L 4 - 182 Show 3D Structure View in InterPro
6TM5 L 4 - 182 Show 3D Structure View in InterPro
6TNT L 4 - 182 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;