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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: SNX7_HUMAN (Q9UNH6)

Summary

This is the summary of UniProt entry SNX7_HUMAN (Q9UNH6).

Description: Sorting nexin-7
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 387 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam PX 28 147
disorder n/a 378 387

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UNH6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDMNSFSPMM PTSPLSMINQ IKFEDEPDLK DLFITVDEPE SHVTTIETFI
50
51
TYRIITKTSR GEFDSSEFEV RRRYQDFLWL KGKLEEAHPT LIIPPLPEKF
100
101
IVKGMVERFN DDFIETRRKA LHKFLNRIAD HPTLTFNEDF KIFLTAQAWE
150
151
LSSHKKQGPG LLSRMGQTVR AVASSMRGVK NRPEEFMEMN NFIELFSQKI
200
201
NLIDKISQRI YKEEREYFDE MKEYGPIHIL WSASEEDLVD TLKDVASCID
250
251
RCCKATEKRM SGLSEALLPV VHEYVLYSEM LMGVMKRRDQ IQAELDSKVE
300
301
VLTYKKADTD LLPEEIGKLE DKVECANNAL KADWERWKQN MQNDIKLAFT
350
351
DMAEENIHYY EQCLATWESF LTSQTNLHLE EASEDKP              
387
 

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Checksums:
CRC64:E703B3EC6013DC1F
MD5:82a7af81e2f475ef779a76aeb6849e79

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PX 28 - 147 3IQ2 A 28 - 147 Jmol OpenAstexViewer
B 28 - 147 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.