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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ANR26_HUMAN (Q9UPS8)

Summary

This is the summary of UniProt entry ANR26_HUMAN (Q9UPS8).

Description: Ankyrin repeat domain-containing protein 26 {ECO:0000305}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1710 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 10 41
low_complexity n/a 14 28
low_complexity n/a 25 33
disorder n/a 46 47
Pfam Ank_2 50 143
Pfam Ank_2 141 209
disorder n/a 218 323
low_complexity n/a 230 249
disorder n/a 325 326
disorder n/a 330 332
disorder n/a 334 398
disorder n/a 401 457
disorder n/a 468 635
low_complexity n/a 527 540
coiled_coil n/a 529 549
low_complexity n/a 566 580
low_complexity n/a 613 629
disorder n/a 639 641
disorder n/a 646 696
low_complexity n/a 648 660
coiled_coil n/a 746 787
coiled_coil n/a 795 871
disorder n/a 806 811
disorder n/a 848 849
disorder n/a 851 853
disorder n/a 855 916
low_complexity n/a 897 907
coiled_coil n/a 907 941
Pfam CCDC144C 914 1217
disorder n/a 928 930
disorder n/a 942 944
coiled_coil n/a 946 973
disorder n/a 953 969
disorder n/a 971 974
coiled_coil n/a 978 1047
disorder n/a 985 1005
disorder n/a 1013 1022
disorder n/a 1024 1031
disorder n/a 1048 1049
coiled_coil n/a 1052 1079
disorder n/a 1078 1080
disorder n/a 1091 1094
coiled_coil n/a 1094 1170
disorder n/a 1105 1110
disorder n/a 1112 1113
disorder n/a 1119 1120
disorder n/a 1143 1162
coiled_coil n/a 1175 1213
disorder n/a 1207 1208
disorder n/a 1235 1236
disorder n/a 1244 1247
coiled_coil n/a 1249 1276
disorder n/a 1263 1271
disorder n/a 1274 1300
coiled_coil n/a 1284 1373
disorder n/a 1316 1320
low_complexity n/a 1328 1343
coiled_coil n/a 1399 1419
coiled_coil n/a 1430 1471
low_complexity n/a 1441 1457
low_complexity n/a 1479 1493
disorder n/a 1514 1516
Pfam DUF3496 1523 1631
coiled_coil n/a 1523 1550
low_complexity n/a 1549 1564
coiled_coil n/a 1566 1586
disorder n/a 1574 1576
disorder n/a 1584 1585
disorder n/a 1599 1603
disorder n/a 1609 1614
disorder n/a 1618 1619
disorder n/a 1632 1640
disorder n/a 1642 1652
disorder n/a 1659 1664
disorder n/a 1671 1682

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UPS8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKKIFSKKGE SPLGSFARRQ RSSAGGGGEP GEGAYSQPGY HVRDRDLGKI
50
51
HKAASAGNVA KVQQILLLRK NGLNDRDKMN RTALHLACAN GHPEVVTLLV
100
101
DRKCQLNVCD NENRTALMKA VQCQEEKCAT ILLEHGADPN LADVHGNTAL
150
151
HYAVYNEDIS VATKLLLYDA NIEAKNKDDL TPLLLAVSGK KQQMVEFLIK
200
201
KKANVNAVDK LESSHQLISE YKEERIPKHS SQNSNSVDES SEDSLSRLSG
250
251
KPGVDDSWPT SDDEDLNFDT KNVPKPSLAK LMTASQQSRK NLEATYGTVR
300
301
TGNRTLFEDR DSDSQDEVVV ESLPTTSIKV QCFSHPTYQS PDLLPKPSHK
350
351
SLANPGLMKE EPTKPGIAKK ENGIDIIESA PLEQTNNDNL TYVDEVHKNN
400
401
RSDMMSALGL GQEEDIESPW DSESISENFP QKYVDPLAGA ADGKEKNIGN
450
451
EQAEDVFYIP SCMSGSRNFK MAKLEDTRNV GMPVAHMESP ERYLHLKPTI
500
501
EMKDSVPNKA GGMKDVQTSK AAEHDLEVAS EEEQEREGSE NNQPQVEEER
550
551
KKHRNNEMEV SANIHDGATD DAEDDDDDDG LIQKRKSGET DHQQFPRKEN
600
601
KEYASSGPAL QMKEVKSTEK EKRTSKESVN SPVFGKASLL TGGLLQVDDD
650
651
SSLSEIDEDE GRPTKKTSNE KNKVKNQIQS MDDVDDLTQS SETASEDCEL
700
701
PHSSYKNFML LIEQLGMECK DSVSLLKIQD AALSCERLLE LKKNHCELLT
750
751
VKIKKMEDKV NVLQRELSET KEIKSQLEHQ KVEWERELCS LRFSLNQEEE
800
801
KRRNADTLYE KIREQLRRKE EQYRKEVEVK QQLELSLQTL EMELRTVKSN
850
851
LNQVVQERND AQRQLSREQN ARMLQDGILT NHLSKQKEIE MAQKKMNSEN
900
901
SHSHEEEKDL SHKNSMLQEE IAMLRLEIDT IKNQNQEKEK KCFEDLKIVK
950
951
EKNEDLQKTI KQNEETLTQT ISQYNGRLSV LTAENAMLNS KLENEKQSKE
1000
1001
RLEAEVESYH SRLAAAIHDR DQSETSKREL ELAFQRARDE CSRLQDKMNF
1050
1051
DVSNLKDNNE ILSQQLFKTE SKLNSLEIEF HHTRDALREK TLGLERVQKD
1100
1101
LSQTQCQMKE MEQKYQNEQV KVNKYIGKQE SVEERLSQLQ SENMLLRQQL
1150
1151
DDAHNKADNK EKTVINIQDQ FHAIVQKLQA ESEKQSLLLE ERNKELISEC
1200
1201
NHLKERQYQY ENEKAEREVV VRQLQQELAD TLKKQSMSEA SLEVTSRYRI
1250
1251
NLEDETQDLK KKLGQIRNQL QEAQDRHTEA VRCAEKMQDH KQKLEKDNAK
1300
1301
LKVTVKKQMD KIEELQKNLL NANLSEDEKE QLKKLMELKQ SLECNLDQEM
1350
1351
KKNVELEREI TGFKNLLKMT RKKLNEYENG EFSFHGDLKT SQFEMDIQIN
1400
1401
KLKHKIDDLT AELETAGSKC LHLDTKNQIL QEELLSMKTV QKKCEKLQKN
1450
1451
KKKLEQEVIN LRSHIERNMV ELGQVKQYKQ EIEERARQEI AEKLKEVNLF
1500
1501
LQAQAASQEN LEQFRENNFA SMKSQMELRI KDLESELSKI KTSQEDFNKT
1550
1551
ELEKYKQLYL EELKVRKSLS SKLTKTNERL AEVNTKLLVE KQQSRSLFTT
1600
1601
LTTRPVMEPP CVGNLNNSLD LNRKLIPREN LVISTSNPRA SNNSMENYLS
1650
1651
KMQQELEKNI TRELKEAAAE LESGSIASPL GSTDESNLNQ DLVWKASREY
1700
1701
VQVLKKNYMI                                            
1710
 

Show the unformatted sequence.

Checksums:
CRC64:01CBF9BADB894872
MD5:93dc46367d36db965251a262d155a174

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;