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6  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MARE3_HUMAN (Q9UPY8)

Summary

This is the summary of UniProt entry MARE3_HUMAN (Q9UPY8).

Description: Microtubule-associated protein RP/EB family member 3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 281 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam CH 14 120
disorder n/a 128 144
disorder n/a 147 149
disorder n/a 156 202
coiled_coil n/a 202 222
Pfam EB1 219 257
disorder n/a 248 249
disorder n/a 260 281
low_complexity n/a 265 279

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UPY8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAVNVYSTSV TSENLSRHDM LAWVNDSLHL NYTKIEQLCS GAAYCQFMDM
50
51
LFPGCVHLRK VKFQAKLEHE YIHNFKVLQA AFKKMGVDKI IPVEKLVKGK
100
101
FQDNFEFIQW FKKFFDANYD GKDYNPLLAR QGQDVAPPPN PGDQIFNKSK
150
151
KLIGTAVPQR TSPTGPKNMQ TSGRLSNVAP PCILRKNPPS ARNGGHETDA
200
201
QILELNQQLV DLKLTVDGLE KERDFYFSKL RDIELICQEH ESENSPVISG
250
251
IIGILYATEE GFAPPEDDEI EEHQQEDQDE Y                    
281
 

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Checksums:
CRC64:0DA45E89A0B993D3
MD5:356e3c5a8e102d4aff8f41da7522c79e

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
CH 14 - 120 1WYO A 21 - 127 Jmol OpenAstexViewer
3CO1 A 14 - 120 Jmol OpenAstexViewer
3JAK M 14 - 120 Jmol OpenAstexViewer
N 14 - 120 Jmol OpenAstexViewer
3JAL M 14 - 120 Jmol OpenAstexViewer
N 14 - 120 Jmol OpenAstexViewer
3JAR M 14 - 120 Jmol OpenAstexViewer
N 14 - 120 Jmol OpenAstexViewer
EB1 219 - 257 3TQ7 B 219 - 257 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.