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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TENN_HUMAN (Q9UQP3)

Summary

This is the summary of UniProt entry TENN_HUMAN (Q9UQP3).

Description: Tenascin-N {ECO:0000312|HGNC:HGNC:22942}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1299 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 28
low_complexity n/a 12 24
disorder n/a 31 36
disorder n/a 57 61
disorder n/a 69 72
coiled_coil n/a 105 125
low_complexity n/a 112 124
Pfam EGF_Tenascin 170 198
Pfam fn3 263 343
Pfam fn3 356 434
disorder n/a 365 371
disorder n/a 392 401
disorder n/a 404 409
disorder n/a 423 424
disorder n/a 434 457
Pfam fn3 444 522
disorder n/a 484 496
disorder n/a 521 539
Pfam fn3 532 611
disorder n/a 542 544
disorder n/a 572 582
disorder n/a 601 633
Pfam fn3 621 699
disorder n/a 658 675
disorder n/a 689 723
Pfam fn3 709 788
disorder n/a 746 764
disorder n/a 778 779
disorder n/a 782 805
Pfam fn3 798 876
disorder n/a 808 810
disorder n/a 828 829
disorder n/a 835 852
disorder n/a 863 893
Pfam fn3 886 964
disorder n/a 916 917
disorder n/a 923 938
disorder n/a 960 988
Pfam fn3 974 1051
disorder n/a 990 991
disorder n/a 1055 1058
disorder n/a 1064 1072
Pfam Fibrinogen_C 1066 1277
disorder n/a 1251 1252
low_complexity n/a 1285 1298

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UQP3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSLQEMFRFP MGLLLGSVLL VASAPATLEP PGCSNKEQQV TVSHTYKIDV
50
51
PKSALVQVDA DPQPLSDDGA SLLALGEARE EQNIIFRHNI RLQTPQKDCE
100
101
LAGSVQDLLA RVKKLEEEMV EMKEQCSAQR CCQGVTDLSR HCSGHGTFSL
150
151
ETCSCHCEEG REGPACERLA CPGACSGHGR CVDGRCLCHE PYVGADCGYP
200
201
ACPENCSGHG ECVRGVCQCH EDFMSEDCSE KRCPGDCSGH GFCDTGECYC
250
251
EEGFTGLDCA QVVTPQGLQL LKNTEDSLLV SWEPSSQVDH YLLSYYPLGK
300
301
ELSGKQIQVP KEQHSYEILG LLPGTKYIVT LRNVKNEVSS SPQHLLATTD
350
351
LAVLGTAWVT DETENSLDVE WENPSTEVDY YKLRYGPMTG QEVAEVTVPK
400
401
SSDPKSRYDI TGLHPGTEYK ITVVPMRGEL EGKPILLNGR TEIDSPTNVV
450
451
TDRVTEDTAT VSWDPVQAVI DKYVVRYTSA DGDTKEMAVH KDESSTVLTG
500
501
LKPGEAYKVY VWAERGNQGS KKADTNALTE IDSPANLVTD RVTENTATIS
550
551
WDPVQATIDK YVVRYTSADD QETREVLVGK EQSSTVLTGL RPGVEYTVHV
600
601
WAQKGDRESK KADTNAPTDI DSPKNLVTDR VTENMATVSW DPVQAAIDKY
650
651
VVRYTSAGGE TREVPVGKEQ SSTVLTGLRP GMEYMVHVWA QKGDQESKKA
700
701
DTKAQTDIDS PQNLVTDRVT ENMATVSWDP VRATIDRYVV RYTSAKDGET
750
751
REVPVGKEQS STVLTGLRPG VEYTVHVWAQ KGAQESKKAD TKAQTDIDSP
800
801
QNLVTDWVTE NTATVSWDPV QATIDRYVVH YTSANGETRE VPVGKEQSST
850
851
VLTGLRPGME YTVHVWAQKG NQESKKADTK AQTEIDGPKN LVTDWVTENM
900
901
ATVSWDPVQA TIDKYMVRYT SADGETREVP VGKEHSSTVL TGLRPGMEYM
950
951
VHVWAQKGAQ ESKKADTKAQ TELDPPRNLR PSAVTQSGGI LTWTPPSAQI
1000
1001
HGYILTYQFP DGTVKEMQLG REDQRFALQG LEQGATYPVS LVAFKGGRRS
1050
1051
RNVSTTLSTV GARFPHPSDC SQVQQNSNAA SGLYTIYLHG DASRPLQVYC
1100
1101
DMETDGGGWI VFQRRNTGQL DFFKRWRSYV EGFGDPMKEF WLGLDKLHNL
1150
1151
TTGTPARYEV RVDLQTANES AYAIYDFFQV ASSKERYKLT VGKYRGTAGD
1200
1201
ALTYHNGWKF TTFDRDNDIA LSNCALTHHG GWWYKNCHLA NPNGRYGETK
1250
1251
HSEGVNWEPW KGHEFSIPYV ELKIRPHGYS REPVLGRKKR TLRGRLRTF 
1299
 

Show the unformatted sequence.

Checksums:
CRC64:CC4BBD5CE47ADBED
MD5:01192f824b6e3687bbba65c3b7409b33

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;