Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HIS4_THEMA (Q9X0C7)

Summary

This is the summary of UniProt entry HIS4_THEMA (Q9X0C7).

Description: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase EC=5.3.1.16
Source organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) (NCBI taxonomy ID 243274)
Length: 241 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam His_biosynth 2 232
disorder n/a 203 204

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9X0C7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLVVPAIDLF RGKVARMIKG RKENTIFYEK DPVELVEKLI EEGFTLIHVV
50
51
DLSNAIENSG ENLPVLEKLS EFAEHIQIGG GIRSLDYAEK LRKLGYRRQI
100
101
VSSKVLEDPS FLKSLREIDV EPVFSLDTRG GRVAFKGWLA EEEIDPVSLL
150
151
KRLKEYGLEE IVHTEIEKDG TLQEHDFSLT KKIAIEAEVK VLAAGGISSE
200
201
NSLKTAQKVH TETNGLLKGV IVGRAFLEGI LTVEVMKRYA R         
241
 

Show the unformatted sequence.

Checksums:
CRC64:B1ABDDE5A4D5213D
MD5:091e3e8d7f2df315d1c02286102ae73b

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
His_biosynth 2 - 232 1QO2 A 2 - 232 Jmol OpenAstexViewer
B 2 - 232 Jmol OpenAstexViewer
2CFF A 2 - 232 Jmol OpenAstexViewer
B 2 - 232 Jmol OpenAstexViewer
2W79 A 2 - 232 Jmol OpenAstexViewer
B 2 - 232 Jmol OpenAstexViewer