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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: VPP2_HUMAN (Q9Y487)

Summary

This is the summary of UniProt entry VPP2_HUMAN (Q9Y487).

Description: V-type proton ATPase 116 kDa subunit a isoform 2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 856 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 22
Pfam V_ATPase_I 27 842
disorder n/a 79 83
disorder n/a 85 92
coiled_coil n/a 94 128
low_complexity n/a 112 124
transmembrane n/a 406 430
low_complexity n/a 418 429
transmembrane n/a 451 468
transmembrane n/a 554 572
transmembrane n/a 584 607
transmembrane n/a 619 635
transmembrane n/a 647 666
low_complexity n/a 659 673
transmembrane n/a 754 774
transmembrane n/a 786 808
low_complexity n/a 839 846

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Y487. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGSLFRSETM CLAQLFLQSG TAYECLSALG EKGLVQFRDL NQNVSSFQRK
50
51
FVGEVKRCEE LERILVYLVQ EINRADIPLP EGEASPPAPP LKQVLEMQEQ
100
101
LQKLEVELRE VTKNKEKLRK NLLELIEYTH MLRVTKTFVK RNVEFEPTYE
150
151
EFPSLESDSL LDYSCMQRLG AKLGFVSGLI NQGKVEAFEK MLWRVCKGYT
200
201
IVSYAELDES LEDPETGEVI KWYVFLISFW GEQIGHKVKK ICDCYHCHVY
250
251
PYPNTAEERR EIQEGLNTRI QDLYTVLHKT EDYLRQVLCK AAESVYSRVI
300
301
QVKKMKAIYH MLNMCSFDVT NKCLIAEVWC PEADLQDLRR ALEEGSRESG
350
351
ATIPSFMNII PTKETPPTRI RTNKFTEGFQ NIVDAYGVGS YREVNPALFT
400
401
IITFPFLFAV MFGDFGHGFV MFLFALLLVL NENHPRLNQS QEIMRMFFNG
450
451
RYILLLMGLF SVYTGLIYND CFSKSVNLFG SGWNVSAMYS SSHPPAEHKK
500
501
MVLWNDSVVR HNSILQLDPS IPGVFRGPYP LGIDPIWNLA TNRLTFLNSF
550
551
KMKMSVILGI IHMTFGVILG IFNHLHFRKK FNIYLVSIPE LLFMLCIFGY
600
601
LIFMIFYKWL VFSAETSRVA PSILIEFINM FLFPASKTSG LYTGQEYVQR
650
651
VLLVVTALSV PVLFLGKPLF LLWLHNGRSC FGVNRSGYTL IRKDSEEEVS
700
701
LLGSQDIEEG NHQVEDGCRE MACEEFNFGE ILMTQVIHSI EYCLGCISNT
750
751
ASYLRLWALS LAHAQLSDVL WAMLMRVGLR VDTTYGVLLL LPVIALFAVL
800
801
TIFILLIMEG LSAFLHAIRL HWVEFQNKFY VGAGTKFVPF SFSLLSSKFN
850
851
NDDSVA                                                
856
 

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Checksums:
CRC64:6C38B36FA33A92BA
MD5:2874ce8ba8b52f020f0cd74b340b27e9

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.