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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MMP24_HUMAN (Q9Y5R2)

Summary

This is the summary of UniProt entry MMP24_HUMAN (Q9Y5R2).

Description: Matrix metalloproteinase-24 EC=3.4.24.-
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 645 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 26
sig_p n/a 1 54
low_complexity n/a 1 24
low_complexity n/a 30 77
Pfam PG_binding_1 76 134
disorder n/a 142 147
disorder n/a 150 155
Pfam Peptidase_M10 162 327
disorder n/a 257 266
disorder n/a 318 321
disorder n/a 323 378
low_complexity n/a 327 345
low_complexity n/a 352 372
Pfam Hemopexin 384 427
Pfam Hemopexin 429 472
Pfam Hemopexin 476 522
Pfam Hemopexin 524 569
Pfam DUF3377 575 645
transmembrane n/a 602 623

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Y5R2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPRSRGGRAA PGPPPPPPPP GQAPRWSRWR VPGRLLLLLL PALCCLPGAA
50
51
RAAAAAAGAG NRAAVAVAVA RADEAEAPFA GQNWLKSYGY LLPYDSRASA
100
101
LHSAKALQSA VSTMQQFYGI PVTGVLDQTT IEWMKKPRCG VPDHPHLSRR
150
151
RRNKRYALTG QKWRQKHITY SIHNYTPKVG ELDTRKAIRQ AFDVWQKVTP
200
201
LTFEEVPYHE IKSDRKEADI MIFFASGFHG DSSPFDGEGG FLAHAYFPGP
250
251
GIGGDTHFDS DEPWTLGNAN HDGNDLFLVA VHELGHALGL EHSSDPSAIM
300
301
APFYQYMETH NFKLPQDDLQ GIQKIYGPPA EPLEPTRPLP TLPVRRIHSP
350
351
SERKHERQPR PPRPPLGDRP STPGTKPNIC DGNFNTVALF RGEMFVFKDR
400
401
WFWRLRNNRV QEGYPMQIEQ FWKGLPARID AAYERADGRF VFFKGDKYWV
450
451
FKEVTVEPGY PHSLGELGSC LPREGIDTAL RWEPVGKTYF FKGERYWRYS
500
501
EERRATDPGY PKPITVWKGI PQAPQGAFIS KEGYYTYFYK GRDYWKFDNQ
550
551
KLSVEPGYPR NILRDWMGCN QKEVERRKER RLPQDDVDIM VTINDVPGSV
600
601
NAVAVVIPCI LSLCILVLVY TIFQFKNKTG PQPVTYYKRP VQEWV     
645
 

Show the unformatted sequence.

Checksums:
CRC64:06B2B76EA3DABB9D
MD5:23731d41729a73de5182bce7e04bbf90

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.