Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
12  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SPIN1_HUMAN (Q9Y657)

Summary

This is the summary of UniProt entry SPIN1_HUMAN (Q9Y657).

Description: Spindlin-1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 262 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 1 60
low_complexity n/a 27 38
Pfam Spin-Ssty 54 103
disorder n/a 69 70
disorder n/a 73 74
Pfam Spin-Ssty 133 182
disorder n/a 192 209
Pfam Spin-Ssty 214 259

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Y657. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKTPFGKTPG QRSRADAGHA GVSANMMKKR TSHKKHRSSV GPSKPVSQPR
50
51
RNIVGCRIQH GWKEGNGPVT QWKGTVLDQV PVNPSLYLIK YDGFDCVYGL
100
101
ELNKDERVSA LEVLPDRVAT SRISDAHLAD TMIGKAVEHM FETEDGSKDE
150
151
WRGMVLARAP VMNTWFYITY EKDPVLYMYQ LLDDYKEGDL RIMPDSNDSP
200
201
PAEREPGEVV DSLVGKQVEY AKEDGSKRTG MVIHQVEAKP SVYFIKFDDD
250
251
FHIYVYDLVK TS                                         
262
 

Show the unformatted sequence.

Checksums:
CRC64:49F86CBCC7A0AA01
MD5:c7bb9450f0fce9a180e42b2b99eb79f9

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Spin-Ssty 133 - 182 2NS2 A 108 - 157 Jmol OpenAstexViewer
B 108 - 157 Jmol OpenAstexViewer
4H75 A 133 - 182 Jmol OpenAstexViewer
4MZF B 133 - 182 Jmol OpenAstexViewer
4MZG B 133 - 182 Jmol OpenAstexViewer
D 133 - 182 Jmol OpenAstexViewer
4MZH A 133 - 182 Jmol OpenAstexViewer
5JSG A 133 - 182 Jmol OpenAstexViewer
B 133 - 182 Jmol OpenAstexViewer
5JSJ A 133 - 182 Jmol OpenAstexViewer
B 133 - 182 Jmol OpenAstexViewer
5Y5W A 133 - 182 Jmol OpenAstexViewer
B 133 - 182 Jmol OpenAstexViewer
C 133 - 182 Jmol OpenAstexViewer
D 133 - 182 Jmol OpenAstexViewer
6I8B B 133 - 182 Jmol OpenAstexViewer
E 133 - 182 Jmol OpenAstexViewer
6I8L B 133 - 182 Jmol OpenAstexViewer
6I8Y A 133 - 182 Jmol OpenAstexViewer
6QPL B 133 - 182 Jmol OpenAstexViewer
214 - 259 2NS2 A 189 - 234 Jmol OpenAstexViewer
B 189 - 234 Jmol OpenAstexViewer
4H75 A 214 - 259 Jmol OpenAstexViewer
4MZF B 214 - 259 Jmol OpenAstexViewer
4MZG B 214 - 259 Jmol OpenAstexViewer
D 214 - 259 Jmol OpenAstexViewer
4MZH A 214 - 259 Jmol OpenAstexViewer
5JSG A 214 - 259 Jmol OpenAstexViewer
B 214 - 259 Jmol OpenAstexViewer
5JSJ A 214 - 259 Jmol OpenAstexViewer
B 214 - 259 Jmol OpenAstexViewer
5Y5W A 214 - 259 Jmol OpenAstexViewer
B 214 - 259 Jmol OpenAstexViewer
C 214 - 259 Jmol OpenAstexViewer
D 214 - 259 Jmol OpenAstexViewer
6I8B B 214 - 259 Jmol OpenAstexViewer
E 214 - 259 Jmol OpenAstexViewer
6I8L B 214 - 259 Jmol OpenAstexViewer
6I8Y A 214 - 259 Jmol OpenAstexViewer
6QPL B 214 - 259 Jmol OpenAstexViewer
54 - 103 2NS2 A 29 - 78 Jmol OpenAstexViewer
B 29 - 78 Jmol OpenAstexViewer
4H75 A 54 - 103 Jmol OpenAstexViewer
4MZF B 54 - 103 Jmol OpenAstexViewer
4MZG B 54 - 103 Jmol OpenAstexViewer
D 54 - 103 Jmol OpenAstexViewer
4MZH A 54 - 103 Jmol OpenAstexViewer
5JSG A 54 - 103 Jmol OpenAstexViewer
B 54 - 103 Jmol OpenAstexViewer
5JSJ A 54 - 103 Jmol OpenAstexViewer
B 54 - 103 Jmol OpenAstexViewer
5Y5W A 54 - 103 Jmol OpenAstexViewer
B 54 - 103 Jmol OpenAstexViewer
C 54 - 103 Jmol OpenAstexViewer
D 54 - 103 Jmol OpenAstexViewer
6I8B B 54 - 103 Jmol OpenAstexViewer
E 54 - 103 Jmol OpenAstexViewer
6I8L B 54 - 103 Jmol OpenAstexViewer
6I8Y A 54 - 103 Jmol OpenAstexViewer
6QPL B 54 - 103 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.