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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: AUP1_HUMAN (Q9Y679)

Summary

This is the summary of UniProt entry AUP1_HUMAN (Q9Y679).

Description: Ancient ubiquitous protein 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 476 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
transmembrane n/a 23 51
low_complexity n/a 23 29
low_complexity n/a 108 122
transmembrane n/a 153 173
low_complexity n/a 159 172
low_complexity n/a 216 228
disorder n/a 321 365
low_complexity n/a 343 358
Pfam CUE 365 403
disorder n/a 410 441
disorder n/a 443 446
disorder n/a 471 476

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Y679. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MELPSGPGPE RLFDSHRLPG DCFLLLVLLL YAPVGFCLLV LRLFLGIHVF
50
51
LVSCALPDSV LRRFVVRTMC AVLGLVARQE DSGLRDHSVR VLISNHVTPF
100
101
DHNIVNLLTT CSTVSESEAE SATGRFPGAQ LKAPLSPLAF RMEDTEALPL
150
151
TPILYPTCQF FFFIFLNIFL LAFSSPGSQP LLNSPPSFVC WSRGFMEMNG
200
201
RGELVESLKR FCASTRLPPT PLLLFPEEEA TNGREGLLRF SSWPFSIQDV
250
251
VQPLTLQVQR PLVSVTVSDA SWVSELLWSL FVPFTVYQVR WLRPVHRQLG
300
301
EANEEFALRV QQLVAKELGQ TGTRLTPADK AEHMKRQRHP RLRPQSAQSS
350
351
FPPSPGPSPD VQLATLAQRV KEVLPHVPLG VIQRDLAKTG CVDLTITNLL
400
401
EGAVAFMPED ITKGTQSLPT ASASKFPSSG PVTPQPTALT FAKSSWARQE
450
451
SLQERKQALY EYARRRFTER RAQEAD                          
476
 

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Checksums:
CRC64:A6AF3AAD84AE86CB
MD5:87bca6e48c19e8a7745b80803da7acac

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
CUE 365 - 403 2EKF A 15 - 53 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.