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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TAF6L_HUMAN (Q9Y6J9)

Summary

This is the summary of UniProt entry TAF6L_HUMAN (Q9Y6J9).

Description: TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 622 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam TAF 9 73
disorder n/a 55 56
disorder n/a 94 95
Pfam TAF6_C 219 331
disorder n/a 375 389
low_complexity n/a 381 391
disorder n/a 411 433
low_complexity n/a 413 428
disorder n/a 455 552
low_complexity n/a 500 523
disorder n/a 558 561
disorder n/a 563 565
low_complexity n/a 565 576
disorder n/a 574 582
disorder n/a 593 600

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Y6J9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSEREERRFV EIPRESVRLM AESTGLELSD EVAALLAEDV CYRLREATQN
50
51
SSQFMKHTKR RKLTVEDFNR ALRWSSVEAV CGYGSQEALP MRPAREGELY
100
101
FPEDREVNLV ELALATNIPK GCAETAVRVH VSYLDGKGNL APQGSVPSAV
150
151
SSLTDDLLKY YHQVTRAVLG DDPQLMKVAL QDLQTNSKIG ALLPYFVYVV
200
201
SGVKSVSHDL EQLHRLLQVA RSLFRNPHLC LGPYVRCLVG SVLYCVLEPL
250
251
AASINPLNDH WTLRDGAALL LSHIFWTHGD LVSGLYQHIL LSLQKILADP
300
301
VRPLCCHYGA VVGLHALGWK AVERVLYPHL STYWTNLQAV LDDYSVSNAQ
350
351
VKADGHKVYG AILVAVERLL KMKAQAAEPN RGGPGGRGCR RLDDLPWDSL
400
401
LFQESSSGGG AEPSFGSGLP LPPGGAGPED PSLSVTLADI YRELYAFFGD
450
451
SLATRFGTGQ PAPTAPRPPG DKKEPAAAPD SVRKMPQLTA SAIVSPHGDE
500
501
SPRGSGGGGP ASASGPAASE SRPLPRVHRA RGAPRQQGPG TGTRDVFQKS
550
551
RFAPRGAPHF RFIIAGRQAG RRCRGRLFQT AFPAPYGPSP ASRYVQKLPM
600
601
IGRTSRPARR WALSDYSLYL PL                              
622
 

Show the unformatted sequence.

Checksums:
CRC64:F294E71AF7D4C8C3
MD5:55fb9317562e55c1ec2c822dddc19e5d

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;