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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ZFP37_HUMAN (Q9Y6Q3)

Summary

This is the summary of UniProt entry ZFP37_HUMAN (Q9Y6Q3).

Description: Zinc finger protein 37 homolog
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 630 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 2 53
Pfam KRAB 40 72
disorder n/a 60 61
disorder n/a 68 69
disorder n/a 71 172
disorder n/a 174 176
disorder n/a 191 241
low_complexity n/a 221 232
low_complexity n/a 228 244
disorder n/a 264 283
Pfam zf-C2H2 293 315
disorder n/a 306 311
disorder n/a 313 314
Pfam zf-C2H2 321 343
disorder n/a 337 339
disorder n/a 365 367
Pfam zf-C2H2 377 399
disorder n/a 393 395
Pfam zf-C2H2 405 427
Pfam zf-C2H2 433 455
Pfam zf-C2H2 461 483
Pfam zf-C2H2 489 511
Pfam zf-C2H2 517 539
disorder n/a 533 535
Pfam zf-C2H2 545 567
disorder n/a 561 563
disorder n/a 565 566
Pfam zf-C2H2 573 595
disorder n/a 589 591
disorder n/a 593 594
Pfam zf-C2H2 601 623
disorder n/a 617 630

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Y6Q3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSVSSGVQIL TKPETVDRRR SAETTKEAGR PLEMAVSEPE ASAAEWKQLD
50
51
PAQSNLYNDV MLENYCNQAS MGCQAPKPDM ISKLEKGEAP WLGKGKRPSQ
100
101
GCPSKIARPK QKETDGKVQK DDDQLENIQK SQNKLLREVA VKKKTQAKKN
150
151
GSDCGSLGKK NNLHKKHVPS KKRLLKFESC GKILKQNLDL PDHSRNCVKR
200
201
KSDAAKEHKK SFNHSLSDTR KGKKQTGKKH EKLSSHSSSD KCNKTGKKHD
250
251
KLCCHSSSHI KQDKIQTGEK HEKSPSLSSS TKHEKPQACV KPYECNQCGK
300
301
VLSHKQGLID HQRVHTGEKP YECNECGIAF SQKSHLVVHQ RTHTGEKPYE
350
351
CIQCGKAHGH KHALTDHLRI HTGEKPYECA ECGKTFRHSS NLIQHVRSHT
400
401
GEKPYECKEC GKSFRYNSSL TEHVRTHTGE IPYECNECGK AFKYSSSLTK
450
451
HMRIHTGEKP FECNECGKAF SKKSHLIIHQ RTHTKEKPYK CNECGKAFGH
500
501
SSSLTYHMRT HTGESPFECN QCGKGFKQIE GLTQHQRVHT GEKPYECNEC
550
551
GKAFSQKSHL IVHQRTHTGE KPYECNECEK AFNAKSQLVI HQRSHTGEKP
600
601
YECNECGKTF KQNASLTKHV KTHSEDKSHE                      
630
 

Show the unformatted sequence.

Checksums:
CRC64:91AB6D25BB0B9C9D
MD5:9c7fb9c6aed7b6156741b997f12afd7f

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;