Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: CMTA1_HUMAN (Q9Y6Y1)

Summary

This is the summary of UniProt entry CMTA1_HUMAN (Q9Y6Y1).

Description: Calmodulin-binding transcription activator 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1673 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
low_complexity n/a 52 67
Pfam CG-1 69 182
disorder n/a 249 251
disorder n/a 259 262
disorder n/a 277 381
low_complexity n/a 308 325
disorder n/a 384 385
disorder n/a 404 405
disorder n/a 407 430
disorder n/a 446 448
disorder n/a 451 458
disorder n/a 466 472
disorder n/a 475 477
disorder n/a 481 491
disorder n/a 494 495
disorder n/a 498 516
disorder n/a 519 520
disorder n/a 523 527
disorder n/a 535 536
disorder n/a 538 545
low_complexity n/a 548 580
disorder n/a 566 569
disorder n/a 571 577
disorder n/a 579 587
disorder n/a 595 624
disorder n/a 626 650
disorder n/a 652 665
disorder n/a 685 686
disorder n/a 688 701
disorder n/a 723 724
disorder n/a 806 808
low_complexity n/a 824 840
Pfam TIG 872 952
disorder n/a 988 1019
low_complexity n/a 994 1025
disorder n/a 1173 1188
disorder n/a 1193 1199
disorder n/a 1208 1316
disorder n/a 1331 1368
disorder n/a 1371 1395
disorder n/a 1397 1400
disorder n/a 1404 1405
disorder n/a 1410 1413
disorder n/a 1415 1431
disorder n/a 1458 1472
low_complexity n/a 1462 1473
disorder n/a 1475 1477
Pfam IQ 1594 1609
disorder n/a 1661 1662
disorder n/a 1667 1669
disorder n/a 1671 1673

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Y6Y1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MWRAEGKWLP KTSRKSVSQS VFCGTSTYCV LNTVPPIEDD HGNSNSSHVK
50
51
IFLPKKLLEC LPKCSSLPKE RHRWNTNEEI AAYLITFEKH EEWLTTSPKT
100
101
RPQNGSMILY NRKKVKYRKD GYCWKKRKDG KTTREDHMKL KVQGVECLYG
150
151
CYVHSSIIPT FHRRCYWLLQ NPDIVLVHYL NVPAIEDCGK PCGPILCSIN
200
201
TDKKEWAKWT KEELIGQLKP MFHGIKWTCS NGNSSSGFSV EQLVQQILDS
250
251
HQTKPQPRTH NCLCTGSLGA GGSVHHKCNS AKHRIISPKV EPRTGGYGSH
300
301
SEVQHNDVSE GKHEHSHSKG SSREKRNGKV AKPVLLHQSS TEVSSTNQVE
350
351
VPDTTQSSPV SISSGLNSDP DMVDSPVVTG VSGMAVASVM GSLSQSATVF
400
401
MSEVTNEAVY TMSPTAGPNH HLLSPDASQG LVLAVSSDGH KFAFPTTGSS
450
451
ESLSMLPTNV SEELVLSTTL DGGRKIPETT MNFDPDCFLN NPKQGQTYGG
500
501
GGLKAEMVSS NIRHSPPGER SFSFTTVLTK EIKTEDTSFE QQMAKEAYSS
550
551
SAAAVAASSL TLTAGSSLLP SGGGLSPSTT LEQMDFSAID SNKDYTSSFS
600
601
QTGHSPHIHQ TPSPSFFLQD ASKPLPVEQN THSSLSDSGG TFVMPTVKTE
650
651
ASSQTSSCSG HVETRIESTS SLHLMQFQAN FQAMTAEGEV TMETSQAAEG
700
701
SEVLLKSGEL QACSSEHYLQ PETNGVIRSA GGVPILPGNV VQGLYPVAQP
750
751
SLGNASNMEL SLDHFDISFS NQFSDLINDF ISVEGGSSTI YGHQLVSGDS
800
801
TALSQSEDGA RAPFTQAEMC LPCCSPQQGS LQLSSSEGGA STMAYMHVAE
850
851
VVSAASAQGT LGMLQQSGRV FMVTDYSPEW SYPEGGVKVL ITGPWQEASN
900
901
NYSCLFDQIS VPASLIQPGV LRCYCPAHDT GLVTLQVAFN NQIISNSVVF
950
951
EYKARALPTL PSSQHDWLSL DDNQFRMSIL ERLEQMERRM AEMTGSQQHK
1000
1001
QASGGGSSGG GSGSGNGGSQ AQCASGTGAL GSCFESRVVV VCEKMMSRAC
1050
1051
WAKSKHLIHS KTFRGMTLLH LAAAQGYATL IQTLIKWRTK HADSIDLELE
1100
1101
VDPLNVDHFS CTPLMWACAL GHLEAAVVLY KWDRRAISIP DSLGRLPLGI
1150
1151
ARSRGHVKLA ECLEHLQRDE QAQLGQNPRI HCPASEEPST ESWMAQWHSE
1200
1201
AISSPEIPKG VTVIASTNPE LRRPRSEPSN YYSSESHKDY PAPKKHKLNP
1250
1251
EYFQTRQEKL LPTALSLEEP NIRKQSPSSK QSVPETLSPS EGVRDFSREL
1300
1301
SPPTPETAAF QASGSQPVGK WNSKDLYIGV STVQVTGNPK GTSVGKEAAP
1350
1351
SQVRPREPMS VLMMANREVV NTELGSYRDS AENEECGQPM DDIQVNMMTL
1400
1401
AEHIIEATPD RIKQENFVPM ESSGLERTDP ATISSTMSWL ASYLADADCL
1450
1451
PSAAQIRSAY NEPLTPSSNT SLSPVGSPVS EIAFEKPNLP SAADWSEFLS
1500
1501
ASTSEKVENE FAQLTLSDHE QRELYEAARL VQTAFRKYKG RPLREQQEVA
1550
1551
AAVIQRCYRK YKQYALYKKM TQAAILIQSK FRSYYEQKKF QQSRRAAVLI
1600
1601
QKYYRSYKKC GKRRQARRTA VIVQQKLRSS LLTKKQDQAA RKIMRFLRRC
1650
1651
RHSPLVDHRL YKRSERIEKG QGT                             
1673
 

Show the unformatted sequence.

Checksums:
CRC64:008AA6A906374C00
MD5:d1be0c1c2e214ae12a69b213462624e2

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
TIG 872 - 952 2CXK A 872 - 952 Jmol OpenAstexViewer
B 872 - 952 Jmol OpenAstexViewer
C 872 - 952 Jmol OpenAstexViewer
D 872 - 952 Jmol OpenAstexViewer
E 872 - 952 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.