Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: PARP1_ARATH (Q9ZP54)

Summary

This is the summary of UniProt entry PARP1_ARATH (Q9ZP54).

Description: Poly [ADP-ribose] polymerase 1
Source organism: Arabidopsis thaliana (Mouse-ear cress) (NCBI taxonomy ID 3702)
Length: 983 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 3 8
Pfam zf-PARP 11 87
low_complexity n/a 14 25
disorder n/a 86 106
low_complexity n/a 89 110
disorder n/a 109 112
Pfam zf-PARP 117 190
disorder n/a 140 141
disorder n/a 145 147
disorder n/a 152 154
low_complexity n/a 161 173
disorder n/a 171 175
low_complexity n/a 185 198
disorder n/a 186 228
disorder n/a 239 247
low_complexity n/a 256 265
disorder n/a 276 283
disorder n/a 286 288
Pfam PADR1 291 342
disorder n/a 343 344
disorder n/a 371 394
Pfam BRCT 394 471
disorder n/a 417 419
Pfam WGR 522 602
disorder n/a 570 571
disorder n/a 598 599
Pfam PARP_reg 634 764
Pfam PARP 778 979
disorder n/a 908 923

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9ZP54. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASPHKPWRA EYAKSSRSSC KTCKSVINKE NFRLGKLVQS THFDGIMPMW
50
51
NHASCILKKT KQIKSVDDVE GIESLRWEDQ QKIRKYVESG AGSNTSTSTG
100
101
TSTSSTANNA KLEYGIEVSQ TSRAGCRKCS EKILKGEVRI FSKPEGPGNK
150
151
GLMWHHAKCF LEMSSSTELE SLSGWRSIPD SDQEALLPLV KKALPAAKTE
200
201
TAEARQTNSR AGTKRKNDSV DNEKSKLAKS SFDMSTSGAL QPCSKEKEME
250
251
AQTKELWDLK DDLKKYVTSA ELREMLEVNE QSTRGSELDL RDKCADGMMF
300
301
GPLALCPMCS GHLSFSGGLY RCHGYISEWS KCSHSTLDPD RIKGKWKIPD
350
351
ETENQFLLKW NKSQKSVKPK RILRPVLSGE TSQGQGSKDA TDSSRSERLA
400
401
DLKVSIAGNT KERQPWKKRI EEAGAEFHAN VKKGTSCLVV CGLTDIRDAE
450
451
MRKARRMKVA IVREDYLVDC FKKQRKLPFD KYKIEDTSES LVTVKVKGRS
500
501
AVHEASGLQE HCHILEDGNS IYNTTLSMSD LSTGINSYYI LQIIQEDKGS
550
551
DCYVFRKWGR VGNEKIGGNK VEEMSKSDAV HEFKRLFLEK TGNTWESWEQ
600
601
KTNFQKQPGK FLPLDIDYGV NKQVAKKEPF QTSSNLAPSL IELMKMLFDV
650
651
ETYRSAMMEF EINMSEMPLG KLSKHNIQKG FEALTEIQRL LTESDPQPTM
700
701
KESLLVDASN RFFTMIPSIH PHIIRDEDDF KSKVKMLEAL QDIEIASRIV
750
751
GFDVDSTESL DDKYKKLHCD ISPLPHDSED YRLIEKYLNT THAPTHTEWS
800
801
LELEEVFALE REGEFDKYAP HREKLGNKML LWHGSRLTNF VGILNQGLRI
850
851
APPEAPATGY MFGKGIYFAD LVSKSAQYCY TCKKNPVGLM LLSEVALGEI
900
901
HELTKAKYMD KPPRGKHSTK GLGKKVPQDS EFAKWRGDVT VPCGKPVSSK
950
951
VKASELMYNE YIVYDTAQVK LQFLLKVRFK HKR                  
983
 

Show the unformatted sequence.

Checksums:
CRC64:468E12A8EF1B6F4F
MD5:85a972951f2d4a5e0cb2afb8378cc2f6

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
zf-PARP 11 - 87 1V9X A 14 - 90 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;