Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
1  structure 1  species 0  interactions 3  sequences 3  architectures

Structure: 2F8X


PDB entry 2f8x: Crystal structure of activated Notch, CSL and MAML on HES-1 promoter DNA sequence
Enlarge image.

PDB entry 2f8x

Crystal structure of activated notch, csl and maml on hes-1 promoter dna sequence

Experiment type: X-ray diffraction, resolution 3.25Å
Release date: 2011-07-13
Authors: Nam, Y., Sliz, P., Blacklow, S.C.
Species: Homo sapiens (Human)


Below is the PDBprint for entry 2f8x.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

Loading domain graphics...

Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
C 34 164 Q06330 48 178 LAG1-DNAbind (PF09271)
C 192 314 Q06330 206 328 BTD (PF09270)
K 1884 1927 P46531 1883 1926 Ank (PF00023)
K 1929 1982 P46531 1928 1981 Ank_4 (PF13637)
K 1971 2059 P46531 1970 2058 Ank_2 (PF12796)
K 2000 2093 P46531 1999 2092 Ank_2 (PF12796)
M 16 70 Q92585 16 70 MamL-1 (PF09596)

Note: This mapping was provided by the PDBe group.

View structure

We provide three different tools for looking at three dimensional structures. More...

View the structure of PDB entry 2f8x in: