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Structure: 3OE0


PDB entry 3oe0: Crystal structure of the CXCR4 chemokine receptor in complex with a cyclic peptide antagonist CVX15
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PDB entry 3oe0

Crystal structure of the cxcr4 chemokine receptor in complex with a cyclic peptide antagonist cvx15

Experiment type: X-ray diffraction, resolution 2.90Å
Release date: 2017-07-26
Authors: Wu, B., Mol, C.D., Han, G.W., Katritch, V., Chien, E.Y.T., Liu, W., Cherezov, V., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
Species: Homo sapiens (Human), Enterobacteria phage T4 (Bacteriophage T4)


Below is the PDBprint for entry 3oe0.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
A 1024 1148 P00720 24 148 Phage_lysozyme (PF00959)
A 25 38 P61073 25 38 CXCR4_N (PF12109)
A 55 302 P61073 55 302 7tm_1 (PF00001)

Note: This mapping was provided by the PDBe group.

View structure

View Pfam families and other data mapped to the structure of PDB entry 3oe0 in InterPro