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Structure: 4CXW


PDB entry 4cxw: Crystal structure of human FTO in complex with subfamily-selective inhibitor 12
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PDB entry 4cxw

Crystal structure of human fto in complex with subfamily-selective inhibitor 12

Experiment type: X-ray diffraction, resolution 3.10Å
Release date: 2018-04-18
Authors: Toh, D.W., Sun, L., Tan, J., Chen, Y., Lau, L.Z.M., Hong, W., Woon, E.C.Y., Gao, Y.G.
Species: Homo sapiens (Human)


Below is the PDBprint for entry 4cxw.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
A 36 325 Q9C0B1 36 325 FTO_NTD (PF12933)
A 329 498 Q9C0B1 329 498 FTO_CTD (PF12934)

Note: This mapping was provided by the PDBe group.

View structure

View Pfam families and other data mapped to the structure of PDB entry 4cxw in InterPro