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Structure: 4K33

Summary

4k33
PDB entry 4k33: Crystal Structure of FGF Receptor 3 (FGFR3) Kinase Domain Harboring the K650E Mutation, a Gain-of-Function Mutation Responsible for Thanatophoric Dysplasia Type II and Spermatocytic Seminoma
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PDB entry 4k33

Crystal structure of fgf receptor 3 (fgfr3) kinase domain harboring the k650e mutation, a gain-of-function mutation responsible for thanatophoric dysplasia type ii and spermatocytic seminoma

Experiment type: X-ray diffraction, resolution 2.34Å
Release date: 2016-12-28
Authors: Huang, Z., Chen, H., Mohammadi, M.
Species: Homo sapiens (Human)

PDBprint

Below is the PDBprint for entry 4k33.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
A 472 748 P22607 472 748 Pkinase_Tyr (PF07714)

Note: This mapping was provided by the PDBe group.

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