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Structure: 5MJA

Summary

5mja
PDB entry 5mja: Kinase domain of human EphB1 bound to a quinazoline-based inhibitor
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PDB entry 5mja

Kinase domain of human ephb1 bound to a quinazoline-based inhibitor

Experiment type: X-ray diffraction, resolution 2.14Å
Release date: 2018-01-24
Authors: Kung, A., Schimpl, M., Chen, Y.-C., Overman, R.C., Zhang, C.
Species: Homo sapiens (Human)

PDBprint

Below is the PDBprint for entry 5mja.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
A 609 616 P54762 609 616 EphA2_TM (PF14575)
A 619 878 P54762 619 878 PK_Tyr_Ser-Thr (PF07714)
B 609 616 P54762 609 616 EphA2_TM (PF14575)
B 619 878 P54762 619 878 PK_Tyr_Ser-Thr (PF07714)

Note: This mapping was provided by the PDBe group.

View structure

View Pfam families and other data mapped to the structure of PDB entry 5mja in InterPro