Summary
PDB entry 6r7h: Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Enlarge image.
PDB entry 6r7h
Structural basis of cullin-2 ring e3 ligase regulation by the cop9 signalosome
Experiment type: | Electron Microscopy, resolution 8.80Å |
Release date: | 2019-09-04 |
Authors: | Faull, S.V., Lau, A.M.C., Beuron, F., Cronin, N.B., Morris, E.P., Politis, A. |
Species: | Homo sapiens (Human) |
PDBprint
Below is the PDBprint for entry 6r7h.
External database links
PDBe | 6r7h |
RCSB PDB | 6r7h |
PDBsum | 6r7h |
CATH | 6r7h |
SCOP | 6r7h |
ECOD | 6r7h |
Proteopedia | 6r7h |
Domain organisation
Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.
Loading domain graphics...
Sequence mapping
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.
PDB | UniProt | Pfam family | ||||
---|---|---|---|---|---|---|
Chain | Start | End | ID | Start | End | |
A | 127 | 309 | Q13098 | 127 | 309 | RPN7 (PF10602) |
A | 324 | 428 | Q13098 | 324 | 428 | PCI (PF01399) |
B | 309 | 413 | P61201 | 309 | 413 | PCI (PF01399) |
C | 258 | 362 | Q9UNS2 | 258 | 362 | PCI (PF01399) |
D | 264 | 363 | Q9BT78 | 264 | 363 | PCI (PF01399) |
D | 365 | 406 | Q9BT78 | 365 | 406 | CSN4_RPN5_eIF3a (PF18420) |
E | 50 | 164 | Q92905 | 50 | 164 | JAB (PF01398) |
E | 251 | 329 | Q92905 | 251 | 329 | CSN5_C (PF18323) |
F | 36 | 148 | Q7L5N1 | 36 | 148 | JAB (PF01398) |
F | 194 | 307 | Q7L5N1 | 194 | 307 | MitMem_reg (PF13012) |
G | 61 | 156 | Q9H9Q2 | 61 | 156 | PCI (PF01399) |
G | 166 | 215 | Q9H9Q2 | 166 | 215 | CSN7a_helixI (PF18392) |
H | 31 | 165 | Q99627 | 31 | 165 | CSN8_PSD8_EIF3K (PF10075) |
O | 14 | 644 | Q13617 | 14 | 644 | Cullin (PF00888) |
P | 4 | 67 | Q15370 | 4 | 67 | ubiquitin (PF00240) |
Q | 17 | 82 | Q15369 | 17 | 82 | Skp1_POZ (PF03931) |
Note: This mapping was provided by the PDBe group.
View structure
We provide three different tools for looking at three dimensional structures. More...
View the structure of PDB entry 6r7h in: