Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
459  structures 930  species 0  interactions 5132  sequences 294  architectures

Clan: Adhesin (CL0204)


Bacterial adhesin superfamily Add an annotation

This superfamily includes a variety of bacterial adhesins that have a jelly-roll beta-barrel fold [1]. These domains are involved in sugar recognition.

This clan contains 13 families and the total number of domains in the clan is 5132. The clan was built by A Bateman.

Literature references

  1. Merckel MC, Tanskanen J, Edelman S, Westerlund-Wikstrom B, Korhonen TK, Goldman A; , J Mol Biol 2003;331:897-905.: The structural basis of receptor-binding by Escherichia coli associated with diarrhea and septicemia. PUBMED:12909017 EPMC:12909017


This clan contains the following 13 member families:

Adhesin_Dr AfaD Antig_Caf1 Collagen_bind DUF1120 Fim-adh_lectin FimA Fimbrial FimH_man-bind PapG_N Saf-Nte_pilin SCPU SdrG_C_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Fimbrial (PF00419) 2144 (41.8%) View
SCPU (PF05229) 1468 (28.6%) View
Collagen_bind (PF05737) 1053 (20.5%) View
FimA (PF16970) 237 (4.6%) View
DUF1120 (PF06551) 116 (2.3%) View
SdrG_C_C (PF10425) 53 (1.0%) View
FimH_man-bind (PF09160) 50 (1.0%) View
AfaD (PF05775) 7 (0.1%) View
Saf-Nte_pilin (PF09460) 3 (0.1%) View
Antig_Caf1 (PF09255) 1 (0.0%) View
Fim-adh_lectin (PF09222) 0 (0.0%) View
PapG_N (PF03627) 0 (0.0%) View
Adhesin_Dr (PF04619) 0 (0.0%) View
Total: 13 Total: 5132 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...