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72  structures 72  species 7  interactions 196  sequences 53  architectures

Clan: Matrix (CL0074)


Retroviral matrix superfamily Add an annotation

This clan brings together matrix proteins from a variety of retroviruses.

This clan contains 6 families and the total number of domains in the clan is 196. The clan was built by A Bateman.


This clan contains the following 6 member families:

Gag_MA Gag_p10 Gag_p15 Gag_p17 Gag_p19 Retro_M

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Gag_MA (PF01140) 75 (38.3%) View
Gag_p10 (PF02337) 53 (27.0%) View
Gag_p17 (PF00540) 45 (23.0%) View
Gag_p19 (PF02228) 20 (10.2%) View
Retro_M (PF02813) 3 (1.5%) View
Gag_p15 (PF08723) 0 (0.0%) View
Total: 6 Total: 196 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 7 interactions for this clan. More...

Interacting families
Gag_MA Gag_MA
Gag_p15 Gag_p15
Gag_p17 Gag_p17
Gag_p24 Gag_p17
MHC_I Gag_p17
RVP Gag_p17


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...