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75  structures 4590  species 0  interactions 12869  sequences 176  architectures

Clan: PepSY (CL0320)


PepSY domain-like superfamily Add an annotation

This family includes the PepSY domain as well as a family of uncharacterised proteins.

This clan contains 8 families and the total number of domains in the clan is 12869. The clan was built by A Bateman.


This clan contains the following 8 member families:

BLIP DUF3192 DUF3862 DUF4309 PepSY PepSY_2 PepSY_like SmpA_OmlA

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
PepSY (PF03413) 5790 (45.0%) View
SmpA_OmlA (PF04355) 3401 (26.4%) View
PepSY_like (PF11396) 1487 (11.6%) View
PepSY_2 (PF13670) 1484 (11.5%) View
DUF4309 (PF14172) 312 (2.4%) View
DUF3192 (PF11399) 227 (1.8%) View
DUF3862 (PF12978) 138 (1.1%) View
BLIP (PF07467) 30 (0.2%) View
Total: 8 Total: 12869 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...