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230  structures 8377  species 0  interactions 73760  sequences 3848  architectures

Clan: Patatin (CL0323)


Patatin/FabD/lysophospholipase-like superfamily Add an annotation

This superfamily of enzymes contains a Ser/Asp catalytic dyad. Members of this superfamily are all serine acylhydrolase enzymes.

This clan contains 4 families and the total number of domains in the clan is 73760. The clan was built by A Bateman.

Literature references

  1. Ghosh M, Tucker DE, Burchett SA, Leslie CC; , Prog Lipid Res. 2006;45:487-510.: Properties of the Group IV phospholipase A2 family. PUBMED:16814865 EPMC:16814865


This clan contains the following 4 member families:

Acyl_transf_1 Patatin PLA2_B SAT

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Acyl_transf_1 (PF00698) 34879 (47.3%) View
Patatin (PF01734) 30896 (41.9%) View
PLA2_B (PF01735) 4509 (6.1%) View
SAT (PF16073) 3476 (4.7%) View
Total: 4 Total: 73760 Clan alignment

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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