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9575  structures 10931  species 0  interactions 2638755  sequences 18282  architectures

Clan: HTH (CL0123)

Summary

Helix-turn-helix clan Add an annotation

This family contains a diverse range of mostly DNA-binding domains that contain a helix-turn-helix motif.

This clan contains 353 families and the total number of domains in the clan is 2638755. The clan was built by A Bateman.

Literature references

  1. Brennan RG, Matthews BW; , J Biol Chem 1989;264:1903-1906.: The helix-turn-helix DNA binding motif. PUBMED:2644244 EPMC:2644244
  2. Brennan RG; , Cell 1993;74:773-776.: The winged-helix DNA-binding motif: another helix-turn-helix takeoff. PUBMED:8374950 EPMC:8374950
  3. Wintjens R, Rooman M; , J Mol Biol 1996;262:294-313.: Structural classification of HTH DNA-binding domains and protein-DNA interaction modes. PUBMED:8831795 EPMC:8831795

Members

This clan contains the following 353 member families:

AbiEi_3_N AbiEi_4 ANAPC2 AphA_like AraR_C Arg_repressor ARID ArsR B-block_TFIIIC B5 Bac_DnaA_C Baculo_PEP_N BetR BHD_3 BLACT_WH Bot1p BrkDBD BsuBI_PstI_RE_N C_LFY_FLO CaiF_GrlA CarD_CdnL_TRCF CDC27 Cdc6_C Cdh1_DBD_1 CDT1 CDT1_C CENP-B_N Costars CPSase_L_D3 Cro Crp CSN4_RPN5_eIF3a CSN8_PSD8_EIF3K CtsR Cullin_Nedd8 CUT CUTL CvfB_WH DBD_HTH DDRGK DEP Dimerisation Dimerisation2 DNA_meth_N DpnI_C DprA_WH DsrC DsrD DUF1016_N DUF1133 DUF1153 DUF1323 DUF134 DUF1441 DUF1492 DUF1495 DUF1670 DUF1804 DUF1819 DUF1836 DUF1870 DUF2089 DUF2250 DUF2316 DUF2513 DUF2582 DUF3116 DUF3253 DUF3853 DUF3860 DUF3908 DUF433 DUF4364 DUF4423 DUF4447 DUF480 DUF4817 DUF5635 DUF573 DUF6088 DUF6262 DUF6362 DUF6432 DUF6462 DUF6471 DUF722 DUF739 DUF742 DUF977 E2F_TDP EAP30 eIF-5_eIF-2B ELL ESCRT-II Ets EutK_C Exc F-112 FaeA Fe_dep_repr_C Fe_dep_repress FeoC FokI_C FokI_N Forkhead FtsK_gamma FUR GcrA GerE GntR GP3_package HARE-HTH HemN_C HNF-1_N Homeobox_KN Homeodomain Homez HPD HrcA_DNA-bdg HSF_DNA-bind HTH_1 HTH_10 HTH_11 HTH_12 HTH_13 HTH_15 HTH_16 HTH_17 HTH_18 HTH_19 HTH_20 HTH_21 HTH_22 HTH_23 HTH_24 HTH_25 HTH_26 HTH_27 HTH_28 HTH_29 HTH_3 HTH_30 HTH_31 HTH_32 HTH_33 HTH_34 HTH_35 HTH_36 HTH_37 HTH_38 HTH_39 HTH_40 HTH_41 HTH_42 HTH_43 HTH_45 HTH_46 HTH_47 HTH_48 HTH_49 HTH_5 HTH_50 HTH_51 HTH_52 HTH_53 HTH_54 HTH_55 HTH_56 HTH_57 HTH_58 HTH_59 HTH_6 HTH_7 HTH_8 HTH_9 HTH_ABP1_N HTH_AraC HTH_AsnC-type HTH_CodY HTH_Crp_2 HTH_DeoR HTH_IclR HTH_Mga HTH_micro HTH_OrfB_IS605 HTH_PafC HTH_ParB HTH_psq HTH_SUN2 HTH_Tnp_1 HTH_Tnp_1_2 HTH_Tnp_4 HTH_Tnp_IS1 HTH_Tnp_IS630 HTH_Tnp_ISL3 HTH_Tnp_Mu_1 HTH_Tnp_Mu_2 HTH_Tnp_Tc3_1 HTH_Tnp_Tc3_2 HTH_Tnp_Tc5 HTH_WhiA HxlR IBD IF2_N IRF KicB KilA-N Kin17_mid KORA KorB La LacI LexA_DNA_bind Linker_histone LZ_Tnp_IS481 MADF_DNA_bdg MAGE MARF1_LOTUS MarR MarR_2 MerR MerR-DNA-bind MerR_1 MerR_2 Mga Mnd1 MogR_DNAbind Mor MotA_activ MqsA_antitoxin MRP-L20 MukE Myb_DNA-bind_2 Myb_DNA-bind_3 Myb_DNA-bind_4 Myb_DNA-bind_5 Myb_DNA-bind_6 Myb_DNA-bind_7 Myb_DNA-binding Neugrin NFRKB_winged NOD2_WH NUMOD1 ORC_WH_C OST-HTH P22_Cro PaaX PadR PapB PAX PCI Penicillinase_R Phage_AlpA Phage_antitermQ Phage_CI_repr Phage_CII Phage_NinH Phage_Nu1 Phage_rep_O Phage_rep_org_N Phage_terminase PheRS_DBD1 PheRS_DBD2 PheRS_DBD3 Pou Pox_D5 PqqD PRC2_HTH_1 PUFD PuR_N Put_DNA-bind_N pXO2-72 Raf1_HTH Rap1-DNA-bind Rep_3 RepA_C RepA_N RepC RepL Replic_Relax RFX_DNA_binding Ribosomal_S18 Ribosomal_S19e Ribosomal_S25 Rio2_N RNA_pol_Rpc34 RNA_pol_Rpc82 RNase_H2-Ydr279 ROQ_II RP-C RPA RPA_C RQC Rrf2 RTP RuvB_C S10_plectin SAC3_GANP SANT_DAMP1_like SatD SelB-wing_1 SelB-wing_2 SelB-wing_3 SgrR_N Sigma54_CBD Sigma54_DBD Sigma70_ECF Sigma70_ner Sigma70_r2 Sigma70_r3 Sigma70_r4 Sigma70_r4_2 SinI Ski_Sno SLIDE Slx4 SMC_Nse1 SMC_ScpB SoPB_HTH SpoIIID SRP19 SRP_SPB STN1_2 Sulfolobus_pRN Suv3_N Swi6_N SWIRM Tau95 TBPIP TEA Terminase_5 TetR_N TFA2_Winged_2 TFIIE_alpha TFIIE_beta TFIIF_alpha TFIIF_beta Tn7_Tnp_TnsA_C Tn916-Xis TraI_2_C Trans_reg_C TrfA TrmB tRNA_bind_2 tRNA_bind_3 Trp_repressor UPF0122 UPF0175 Vir_act_alpha_C YdaS_antitoxin YjcQ YokU z-alpha

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...

Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
TetR_N (PF00440) 176495 (6.7%) View
HTH_1 (PF00126) 142066 (5.4%) View
Sigma70_r2 (PF04542) 128369 (4.9%) View
HTH_18 (PF12833) 125317 (4.7%) View
GntR (PF00392) 104095 (3.9%) View
Trans_reg_C (PF00486) 102612 (3.9%) View
GerE (PF00196) 99861 (3.8%) View
Sigma70_r4_2 (PF08281) 87692 (3.3%) View
HTH_3 (PF01381) 85850 (3.3%) View
Homeodomain (PF00046) 85650 (3.2%) View
Myb_DNA-binding (PF00249) 85525 (3.2%) View
LacI (PF00356) 56871 (2.2%) View
MarR_2 (PF12802) 44944 (1.7%) View
HTH_31 (PF13560) 42884 (1.6%) View
Sigma70_r4 (PF04545) 39625 (1.5%) View
MerR_1 (PF13411) 39274 (1.5%) View
HTH_8 (PF02954) 36806 (1.4%) View
MarR (PF01047) 35475 (1.3%) View
HTH_IclR (PF09339) 31118 (1.2%) View
HTH_20 (PF12840) 29236 (1.1%) View
HTH_24 (PF13412) 27166 (1.0%) View
HxlR (PF01638) 24387 (0.9%) View
HTH_5 (PF01022) 24116 (0.9%) View
PCI (PF01399) 23885 (0.9%) View
HTH_Crp_2 (PF13545) 23837 (0.9%) View
Sigma70_r3 (PF04539) 23395 (0.9%) View
HTH_17 (PF12728) 23202 (0.9%) View
PadR (PF03551) 22963 (0.9%) View
HTH_11 (PF08279) 19477 (0.7%) View
Myb_DNA-bind_6 (PF13921) 19031 (0.7%) View
FUR (PF01475) 18551 (0.7%) View
HTH_DeoR (PF08220) 18176 (0.7%) View
Forkhead (PF00250) 17614 (0.7%) View
HTH_30 (PF13556) 16928 (0.6%) View
HTH_Tnp_1 (PF01527) 16253 (0.6%) View
Rrf2 (PF02082) 15820 (0.6%) View
HTH_AsnC-type (PF13404) 15406 (0.6%) View
DEP (PF00610) 13730 (0.5%) View
Myb_DNA-bind_4 (PF13837) 12954 (0.5%) View
Homeobox_KN (PF05920) 12781 (0.5%) View
HTH_6 (PF01418) 12156 (0.5%) View
IF2_N (PF04760) 12090 (0.5%) View
CarD_CdnL_TRCF (PF02559) 11596 (0.4%) View
ARID (PF01388) 11410 (0.4%) View
HTH_21 (PF13276) 11094 (0.4%) View
MerR (PF00376) 11065 (0.4%) View
CPSase_L_D3 (PF02787) 10938 (0.4%) View
HSF_DNA-bind (PF00447) 10917 (0.4%) View
NOD2_WH (PF17779) 10657 (0.4%) View
Ets (PF00178) 10596 (0.4%) View
Ribosomal_S18 (PF01084) 10489 (0.4%) View
SRP_SPB (PF02978) 10083 (0.4%) View
B5 (PF03484) 9669 (0.4%) View
OST-HTH (PF12872) 9192 (0.3%) View
HTH_Tnp_Tc5 (PF03221) 8490 (0.3%) View
RQC (PF09382) 8386 (0.3%) View
Bac_DnaA_C (PF08299) 8270 (0.3%) View
Penicillinase_R (PF03965) 8259 (0.3%) View
HTH_ParB (PF17762) 8201 (0.3%) View
FtsK_gamma (PF09397) 8111 (0.3%) View
Linker_histone (PF00538) 8064 (0.3%) View
Cullin_Nedd8 (PF10557) 7801 (0.3%) View
RuvB_C (PF05491) 7606 (0.3%) View
Myb_DNA-bind_3 (PF12776) 7513 (0.3%) View
La (PF05383) 7436 (0.3%) View
HemN_C (PF06969) 7152 (0.3%) View
E2F_TDP (PF02319) 7148 (0.3%) View
SWIRM (PF04433) 7098 (0.3%) View
MerR-DNA-bind (PF09278) 7001 (0.3%) View
Fe_dep_repr_C (PF02742) 6796 (0.3%) View
SMC_ScpB (PF04079) 6628 (0.3%) View
LexA_DNA_bind (PF01726) 6587 (0.2%) View
Fe_dep_repress (PF01325) 6580 (0.2%) View
HTH_42 (PF06224) 5968 (0.2%) View
HTH_23 (PF13384) 5853 (0.2%) View
MADF_DNA_bdg (PF10545) 5483 (0.2%) View
PAX (PF00292) 5446 (0.2%) View
HTH_OrfB_IS605 (PF12323) 5258 (0.2%) View
HTH_Tnp_Tc3_2 (PF01498) 5131 (0.2%) View
CUT (PF02376) 5071 (0.2%) View
Sigma54_DBD (PF04552) 5018 (0.2%) View
Pou (PF00157) 5015 (0.2%) View
Sigma54_CBD (PF04963) 4975 (0.2%) View
DUF742 (PF05331) 4923 (0.2%) View
DprA_WH (PF17782) 4919 (0.2%) View
HTH_19 (PF12844) 4790 (0.2%) View
Dimerisation (PF08100) 4664 (0.2%) View
HTH_38 (PF13936) 4630 (0.2%) View
HTH_psq (PF05225) 4467 (0.2%) View
HTH_25 (PF13413) 4456 (0.2%) View
SAC3_GANP (PF03399) 4428 (0.2%) View
HTH_28 (PF13518) 4417 (0.2%) View
CSN8_PSD8_EIF3K (PF10075) 4277 (0.2%) View
RFX_DNA_binding (PF02257) 4271 (0.2%) View
HTH_7 (PF02796) 4162 (0.2%) View
eIF-5_eIF-2B (PF01873) 4147 (0.2%) View
MAGE (PF01454) 3856 (0.1%) View
Arg_repressor (PF01316) 3780 (0.1%) View
HTH_48 (PF17906) 3588 (0.1%) View
Vir_act_alpha_C (PF10400) 3555 (0.1%) View
AraR_C (PF19368) 3539 (0.1%) View
PqqD (PF05402) 3519 (0.1%) View
HTH_32 (PF13565) 3518 (0.1%) View
TrmB (PF01978) 3410 (0.1%) View
BLACT_WH (PF17778) 3354 (0.1%) View
KilA-N (PF04383) 3329 (0.1%) View
EAP30 (PF04157) 3291 (0.1%) View
HTH_WhiA (PF02650) 3265 (0.1%) View
DUF433 (PF04255) 3213 (0.1%) View
Mga (PF05043) 3209 (0.1%) View
IRF (PF00605) 3096 (0.1%) View
Put_DNA-bind_N (PF06971) 3034 (0.1%) View
HTH_27 (PF13463) 3001 (0.1%) View
TEA (PF01285) 2973 (0.1%) View
Sigma70_ner (PF04546) 2854 (0.1%) View
Dimerisation2 (PF16864) 2838 (0.1%) View
CENP-B_N (PF04218) 2816 (0.1%) View
Myb_DNA-bind_5 (PF13873) 2809 (0.1%) View
HTH_29 (PF13551) 2738 (0.1%) View
Phage_AlpA (PF05930) 2726 (0.1%) View
HTH_40 (PF14493) 2520 (0.1%) View
HTH_Tnp_4 (PF13613) 2491 (0.1%) View
HTH_33 (PF13592) 2487 (0.1%) View
HARE-HTH (PF05066) 2486 (0.1%) View
CvfB_WH (PF17783) 2459 (0.1%) View
DUF1016_N (PF17761) 2452 (0.1%) View
Ribosomal_S19e (PF01090) 2450 (0.1%) View
HTH_34 (PF13601) 2437 (0.1%) View
SLIDE (PF09111) 2395 (0.1%) View
Ski_Sno (PF02437) 2393 (0.1%) View
S10_plectin (PF03501) 2311 (0.1%) View
HTH_36 (PF13730) 2310 (0.1%) View
Cdc6_C (PF09079) 2262 (0.1%) View
PaaX (PF07848) 2207 (0.1%) View
Ribosomal_S25 (PF03297) 2184 (0.1%) View
RNA_pol_Rpc34 (PF05158) 2093 (0.1%) View
BHD_3 (PF10405) 2062 (0.1%) View
TFIIE_alpha (PF02002) 2028 (0.1%) View
SRP19 (PF01922) 1977 (0.1%) View
ORC_WH_C (PF18137) 1974 (0.1%) View
HTH_22 (PF13309) 1945 (0.1%) View
TFIIF_beta (PF02270) 1919 (0.1%) View
Sigma70_ECF (PF07638) 1892 (0.1%) View
HTH_50 (PF18024) 1880 (0.1%) View
Trp_repressor (PF01371) 1879 (0.1%) View
Myb_DNA-bind_7 (PF15963) 1854 (0.1%) View
Rep_3 (PF01051) 1833 (0.1%) View
UPF0122 (PF04297) 1815 (0.1%) View
Rio2_N (PF09202) 1811 (0.1%) View
RPA_C (PF08784) 1791 (0.1%) View
tRNA_bind_2 (PF13725) 1781 (0.1%) View
HrcA_DNA-bdg (PF03444) 1746 (0.1%) View
Tau95 (PF09734) 1727 (0.1%) View
HTH_37 (PF13744) 1726 (0.1%) View
Kin17_mid (PF10357) 1709 (0.1%) View
SelB-wing_3 (PF09107) 1709 (0.1%) View
B-block_TFIIIC (PF04182) 1686 (0.1%) View
HTH_Tnp_ISL3 (PF13542) 1679 (0.1%) View
TFIIF_alpha (PF05793) 1677 (0.1%) View
PheRS_DBD3 (PF18553) 1626 (0.1%) View
SANT_DAMP1_like (PF16282) 1620 (0.1%) View
DUF573 (PF04504) 1593 (0.1%) View
CDC27 (PF09507) 1589 (0.1%) View
HNF-1_N (PF04814) 1588 (0.1%) View
ESCRT-II (PF05871) 1587 (0.1%) View
AbiEi_4 (PF13338) 1527 (0.1%) View
TFA2_Winged_2 (PF18121) 1498 (0.1%) View
RNA_pol_Rpc82 (PF05645) 1490 (0.1%) View
DsrC (PF04358) 1489 (0.1%) View
GcrA (PF07750) 1481 (0.1%) View
SMC_Nse1 (PF07574) 1468 (0.1%) View
CDT1_C (PF16679) 1447 (0.1%) View
HTH_9 (PF08221) 1446 (0.1%) View
RNase_H2-Ydr279 (PF09468) 1444 (0.1%) View
DUF4817 (PF16087) 1439 (0.1%) View
RPA (PF10134) 1432 (0.1%) View
TFIIE_beta (PF02186) 1416 (0.1%) View
continued
Pfam family Num. domains Alignment
MerR_2 (PF13591) 1383 (0.1%) View
UPF0175 (PF03683) 1360 (0.1%) View
Mnd1 (PF03962) 1355 (0.1%) View
CDT1 (PF08839) 1352 (0.1%) View
HTH_PafC (PF19187) 1349 (0.1%) View
ANAPC2 (PF08672) 1324 (0.1%) View
LZ_Tnp_IS481 (PF13011) 1299 (0.0%) View
ELL (PF10390) 1250 (0.0%) View
TBPIP (PF07106) 1169 (0.0%) View
DUF1153 (PF06627) 1169 (0.0%) View
HTH_CodY (PF08222) 1140 (0.0%) View
Costars (PF14705) 1121 (0.0%) View
Pox_D5 (PF03288) 1117 (0.0%) View
SpoIIID (PF12116) 1116 (0.0%) View
PRC2_HTH_1 (PF18118) 1114 (0.0%) View
DUF1836 (PF08876) 1106 (0.0%) View
CtsR (PF05848) 1097 (0.0%) View
RP-C (PF03428) 1077 (0.0%) View
HTH_16 (PF12645) 1070 (0.0%) View
DUF134 (PF02001) 1054 (0.0%) View
SelB-wing_2 (PF09106) 1039 (0.0%) View
Myb_DNA-bind_2 (PF08914) 1038 (0.0%) View
DUF480 (PF04337) 1027 (0.0%) View
PuR_N (PF09182) 1013 (0.0%) View
DUF6088 (PF19570) 995 (0.0%) View
HPD (PF05044) 983 (0.0%) View
Mor (PF08765) 948 (0.0%) View
Slx4 (PF09494) 947 (0.0%) View
Neugrin (PF06413) 935 (0.0%) View
Replic_Relax (PF13814) 919 (0.0%) View
Bot1p (PF12298) 906 (0.0%) View
DUF3253 (PF11625) 894 (0.0%) View
HTH_12 (PF08461) 880 (0.0%) View
RepA_N (PF06970) 878 (0.0%) View
DDRGK (PF09756) 868 (0.0%) View
HTH_58 (PF19575) 864 (0.0%) View
z-alpha (PF02295) 862 (0.0%) View
ROQ_II (PF18386) 850 (0.0%) View
HTH_Tnp_IS630 (PF01710) 813 (0.0%) View
CUTL (PF16557) 790 (0.0%) View
PheRS_DBD1 (PF18552) 783 (0.0%) View
MRP-L20 (PF12824) 753 (0.0%) View
HTH_AraC (PF00165) 742 (0.0%) View
DUF2089 (PF09862) 740 (0.0%) View
HTH_35 (PF13693) 721 (0.0%) View
PUFD (PF16553) 690 (0.0%) View
Homez (PF11569) 669 (0.0%) View
HTH_51 (PF18558) 661 (0.0%) View
Phage_rep_org_N (PF09681) 642 (0.0%) View
SgrR_N (PF12793) 631 (0.0%) View
Phage_CI_repr (PF07022) 625 (0.0%) View
Terminase_5 (PF06056) 623 (0.0%) View
SinI (PF08671) 622 (0.0%) View
DUF4364 (PF14277) 614 (0.0%) View
MARF1_LOTUS (PF19687) 602 (0.0%) View
SatD (PF16264) 585 (0.0%) View
HTH_SUN2 (PF18580) 576 (0.0%) View
DUF1492 (PF07374) 571 (0.0%) View
Suv3_N (PF18114) 544 (0.0%) View
HTH_Tnp_Tc3_1 (PF11427) 535 (0.0%) View
MqsA_antitoxin (PF15731) 528 (0.0%) View
FeoC (PF09012) 523 (0.0%) View
DUF1819 (PF08849) 519 (0.0%) View
YdaS_antitoxin (PF15943) 512 (0.0%) View
Crp (PF00325) 509 (0.0%) View
AbiEi_3_N (PF17194) 499 (0.0%) View
BrkDBD (PF09607) 490 (0.0%) View
HTH_45 (PF14947) 472 (0.0%) View
Tn916-Xis (PF09035) 472 (0.0%) View
PheRS_DBD2 (PF18554) 454 (0.0%) View
DUF6262 (PF19776) 434 (0.0%) View
NUMOD1 (PF07453) 419 (0.0%) View
NFRKB_winged (PF14465) 413 (0.0%) View
HTH_ABP1_N (PF18107) 398 (0.0%) View
CSN4_RPN5_eIF3a (PF18420) 388 (0.0%) View
RepA_C (PF04796) 385 (0.0%) View
HTH_47 (PF16221) 384 (0.0%) View
HTH_Tnp_Mu_1 (PF02316) 375 (0.0%) View
Cdh1_DBD_1 (PF18196) 373 (0.0%) View
DUF2582 (PF10771) 361 (0.0%) View
STN1_2 (PF09170) 356 (0.0%) View
Tn7_Tnp_TnsA_C (PF08721) 340 (0.0%) View
HTH_13 (PF11972) 340 (0.0%) View
DUF2513 (PF10711) 337 (0.0%) View
HTH_52 (PF18576) 329 (0.0%) View
Raf1_HTH (PF18579) 319 (0.0%) View
DBD_HTH (PF18430) 318 (0.0%) View
DUF6362 (PF19889) 315 (0.0%) View
Phage_rep_O (PF04492) 313 (0.0%) View
BetR (PF08667) 304 (0.0%) View
SoPB_HTH (PF18090) 302 (0.0%) View
Phage_antitermQ (PF06530) 301 (0.0%) View
DUF4423 (PF14394) 300 (0.0%) View
HTH_39 (PF14090) 293 (0.0%) View
HTH_Tnp_Mu_2 (PF09039) 282 (0.0%) View
BsuBI_PstI_RE_N (PF17728) 262 (0.0%) View
TraI_2_C (PF07515) 260 (0.0%) View
IBD (PF10416) 255 (0.0%) View
DUF6471 (PF20075) 253 (0.0%) View
DUF6462 (PF20063) 250 (0.0%) View
MukE (PF04288) 245 (0.0%) View
GP3_package (PF16677) 245 (0.0%) View
HTH_Tnp_IS1 (PF12759) 241 (0.0%) View
Phage_terminase (PF10668) 241 (0.0%) View
KicB (PF03882) 235 (0.0%) View
HTH_Mga (PF08280) 234 (0.0%) View
KorB (PF08535) 232 (0.0%) View
HTH_43 (PF09904) 220 (0.0%) View
HTH_41 (PF14502) 216 (0.0%) View
DUF739 (PF05339) 212 (0.0%) View
C_LFY_FLO (PF17538) 211 (0.0%) View
FaeA (PF04703) 211 (0.0%) View
HTH_53 (PF18606) 200 (0.0%) View
tRNA_bind_3 (PF17176) 195 (0.0%) View
RepL (PF05732) 193 (0.0%) View
HTH_59 (PF20038) 176 (0.0%) View
Phage_CII (PF05269) 175 (0.0%) View
HTH_Tnp_1_2 (PF13022) 174 (0.0%) View
Phage_Nu1 (PF07471) 171 (0.0%) View
DUF1804 (PF08822) 150 (0.0%) View
P22_Cro (PF14549) 149 (0.0%) View
TrfA (PF07042) 147 (0.0%) View
YokU (PF14122) 140 (0.0%) View
DUF3853 (PF12964) 133 (0.0%) View
HTH_46 (PF15977) 129 (0.0%) View
YjcQ (PF09639) 118 (0.0%) View
DUF1323 (PF07037) 117 (0.0%) View
DUF2250 (PF10007) 112 (0.0%) View
HTH_56 (PF18662) 109 (0.0%) View
DUF2316 (PF10078) 108 (0.0%) View
DUF6432 (PF20024) 106 (0.0%) View
DsrD (PF08679) 106 (0.0%) View
HTH_15 (PF12324) 104 (0.0%) View
RTP (PF02334) 103 (0.0%) View
DUF1441 (PF07278) 99 (0.0%) View
DpnI_C (PF17726) 98 (0.0%) View
DNA_meth_N (PF18284) 96 (0.0%) View
DUF1670 (PF07900) 93 (0.0%) View
Phage_NinH (PF06322) 92 (0.0%) View
Exc (PF07825) 92 (0.0%) View
Rap1-DNA-bind (PF09197) 83 (0.0%) View
KORA (PF16509) 82 (0.0%) View
Cro (PF09048) 66 (0.0%) View
HTH_49 (PF18010) 61 (0.0%) View
ArsR (PF09824) 59 (0.0%) View
AphA_like (PF14557) 59 (0.0%) View
RepC (PF06504) 59 (0.0%) View
HTH_55 (PF18622) 57 (0.0%) View
DUF1870 (PF08965) 54 (0.0%) View
HTH_54 (PF18607) 53 (0.0%) View
DUF977 (PF06163) 51 (0.0%) View
DUF722 (PF05263) 49 (0.0%) View
MotA_activ (PF09114) 47 (0.0%) View
CaiF_GrlA (PF07180) 36 (0.0%) View
HTH_micro (PF17007) 31 (0.0%) View
DUF1495 (PF07381) 29 (0.0%) View
FokI_C (PF02980) 28 (0.0%) View
EutK_C (PF16365) 27 (0.0%) View
DUF5635 (PF18685) 26 (0.0%) View
FokI_N (PF02981) 26 (0.0%) View
Baculo_PEP_N (PF04512) 25 (0.0%) View
HTH_57 (PF18679) 23 (0.0%) View
DUF1133 (PF06576) 21 (0.0%) View
Swi6_N (PF18530) 20 (0.0%) View
DUF4447 (PF14590) 18 (0.0%) View
DUF3908 (PF13048) 17 (0.0%) View
DUF3116 (PF11313) 17 (0.0%) View
PapB (PF03333) 16 (0.0%) View
Sulfolobus_pRN (PF05584) 15 (0.0%) View
MogR_DNAbind (PF12181) 8 (0.0%) View
pXO2-72 (PF17443) 6 (0.0%) View
SelB-wing_1 (PF09105) 3 (0.0%) View
F-112 (PF09645) 3 (0.0%) View
DUF3860 (PF12976) 2 (0.0%) View
HTH_26 (PF13443) 0 (0.0%) View
HTH_10 (PF04967) 0 (0.0%) View
Total: 353 Total: 2638755
No alignment ℹ
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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