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262  structures 8239  species 0  interactions 72059  sequences 1427  architectures

Clan: UBA (CL0214)

Summary

UBA superfamily Add an annotation

This superfamily includes domains related to the UBA domain. These domains are often involved in ubiquitin binding.

This clan contains 21 families and the total number of domains in the clan is 72059. The clan was built by A Bateman.

Members

This clan contains the following 21 member families:

CRAL_TRIO_N CUE DMA DUF1421 E3_UbLigase_EDD E3_UbLigase_RBR GIP1_N HBS1_N HOIP-UBA HYPK_UBA Regnase_1_C RuvA_C TAP_C UBA UBA_2 UBA_3 UBA_4 UBA_5 UBA_6 Ubiq-assoc WIYLD

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
UBA (PF00627) 22606 (31.4%) View
CRAL_TRIO_N (PF03765) 10163 (14.1%) View
UBA_4 (PF14555) 8376 (11.6%) View
CUE (PF02845) 7787 (10.8%) View
RuvA_C (PF07499) 7251 (10.1%) View
HYPK_UBA (PF19026) 3824 (5.3%) View
TAP_C (PF03943) 1584 (2.2%) View
GIP1_N (PF06972) 1368 (1.9%) View
HBS1_N (PF08938) 1245 (1.7%) View
UBA_6 (PF18039) 1223 (1.7%) View
WIYLD (PF10440) 999 (1.4%) View
continued
Pfam family Num. domains Alignment
Regnase_1_C (PF18561) 869 (1.2%) View
DMA (PF03474) 780 (1.1%) View
DUF1421 (PF07223) 675 (0.9%) View
UBA_2 (PF08587) 667 (0.9%) View
UBA_3 (PF09288) 630 (0.9%) View
E3_UbLigase_EDD (PF11547) 594 (0.8%) View
E3_UbLigase_RBR (PF18091) 553 (0.8%) View
HOIP-UBA (PF16678) 504 (0.7%) View
UBA_5 (PF16577) 337 (0.5%) View
Ubiq-assoc (PF09145) 24 (0.0%) View
Total: 21 Total: 72059 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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