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871  structures 7940  species 0  interactions 113450  sequences 1285  architectures

Family: ADH_zinc_N (PF00107)

Summary: Zinc-binding dehydrogenase

Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.

The Pfam group coordinates the annotation of Pfam families in Wikipedia, but we have not yet assigned a Wikipedia article to this family. If you think that a particular Wikipedia article provides good annotation, please let us know.

This tab holds annotation information from the InterPro database.

InterPro entry IPR013149

Alcohol dehydrogenase ( EC ) (ADH) catalyzes the reversible oxidation of alcohols to their corresponding acetaldehyde or ketone with the concomitant reduction of NAD: alcohol + NAD = aldehyde or ketone + NADH Currently three structurally and catalytically different types of alcohol dehydrogenases are known:

  1. Zinc-containing 'long-chain' alcohol dehydrogenases.
  2. Insect-type, or 'short-chain' alcohol dehydrogenases.
  3. Iron-containing alcohol dehydrogenases.
Zinc-containing ADH's [ PUBMED:3622514 , PUBMED:1593644 ] are dimeric or tetrameric enzymes that bind two atoms of zinc per subunit. One of the zinc atom is essential for catalytic activity while the other is not. Both zinc atoms are coordinated by either cysteine or histidine residues; the catalytic zinc is coordinated by two cysteines and one histidine. Zinc-containing ADH's are found in bacteria, mammals, plants, and in fungi. In many species there is more than one isozyme (for example, humans have at least six isozymes, yeast have three, etc.). A number of other zinc-dependent dehydrogenases are closely related to zinc ADH [ PUBMED:8504864 ] and are included in this family.
  • Sorbitol dehydrogenase ( EC )
  • L-threonine 3-dehydrogenase ( EC )
  • Glutathione-dependent formaldehyde dehydrogenase ( EC )
  • Mannitol dehydrogenase ( EC )

In addition, this family includes NADP-dependent quinone oxidoreductase ( EC ), an enzyme found in bacteria (gene qor), in yeast and in mammals where, in some species such as rodents, it has been recruited as an eye lens protein and is known as zeta-crystallin [ PUBMED:8486156 ]. The sequence of quinone oxidoreductase is distantly related to that other zinc-containing alcohol dehydrogenases and it lacks the zinc-ligand residues. The torpedo fish and mammalian synaptic vesicle membrane protein vat-1 is related to qor.

This entry represents the cofactor-binding domain of these enzymes, which is normally found towards the C terminus. Structural studies indicate that it forms a classical Rossman fold that reversibly binds NAD(H) [ PUBMED:12962626 , PUBMED:12627956 , PUBMED:7602590 ].

Gene Ontology

The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.

Domain organisation

Below is a listing of the unique domain organisations or architectures in which this domain is found. More...

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Pfam Clan

This family is a member of clan NADP_Rossmann (CL0063), which has the following description:

A class of redox enzymes are two domain proteins. One domain, termed the catalytic domain, confers substrate specificity and the precise reaction of the enzyme. The other domain, which is common to this class of redox enzymes, is a Rossmann-fold domain. The Rossmann domain binds nicotinamide adenine dinucleotide (NAD+) and it is this cofactor that reversibly accepts a hydride ion, which is lost or gained by the substrate in the redox reaction. Rossmann domains have an alpha/beta fold, which has a central beta sheet, with approximately five alpha helices found surrounding the beta sheet.The strands forming the beta sheet are found in the following characteristic order 654123. The inter sheet crossover of the stands in the sheet form the NAD+ binding site [1]. In some more distantly relate Rossmann domains the NAD+ cofactor is replaced by the functionally similar cofactor FAD.

The clan contains the following 206 members:

2-Hacid_dh_C 3Beta_HSD 3HCDH_N 3HCDH_RFF adh_short adh_short_C2 ADH_zinc_N ADH_zinc_N_2 AdoHcyase_NAD AdoMet_MTase AlaDh_PNT_C Amino_oxidase ApbA AviRa B12-binding Bac_GDH Bin3 Bmt2 CbiJ CheR CMAS CmcI CoA_binding CoA_binding_2 CoA_binding_3 Cons_hypoth95 CoV_ExoN CoV_Methyltr_2 DAO DapB_N DFP DNA_methylase DOT1 DRE2_N DREV DUF1442 DUF1611_N DUF166 DUF1776 DUF2431 DUF268 DUF2855 DUF3410 DUF364 DUF43 DUF5129 DUF5130 DUF6094 DUF938 DXP_reductoisom DXPR_C Eco57I ELFV_dehydrog Eno-Rase_FAD_bd Eno-Rase_NADH_b Enoyl_reductase Epimerase F420_oxidored FAD_binding_2 FAD_binding_3 FAD_oxidored Fibrillarin FMO-like FmrO FtsJ fvmX7 G6PD_N GCD14 GDI GDP_Man_Dehyd GFO_IDH_MocA GIDA GidB GLF Glu_dehyd_C Glyco_hydro_4 Glyco_tran_WecG GMC_oxred_N Gp_dh_N GRAS GRDA HcgC HI0933_like HIM1 IlvN ISPD_C K_oxygenase KR LCM Ldh_1_N LpxI_N Lycopene_cycl Malic_M Mannitol_dh MCRA Met_10 Methyltr_RsmB-F Methyltr_RsmF_N Methyltrans_Mon Methyltrans_SAM Methyltransf_10 Methyltransf_11 Methyltransf_12 Methyltransf_14 Methyltransf_15 Methyltransf_16 Methyltransf_17 Methyltransf_18 Methyltransf_19 Methyltransf_2 Methyltransf_20 Methyltransf_21 Methyltransf_22 Methyltransf_23 Methyltransf_24 Methyltransf_25 Methyltransf_28 Methyltransf_29 Methyltransf_3 Methyltransf_30 Methyltransf_31 Methyltransf_32 Methyltransf_33 Methyltransf_34 Methyltransf_4 Methyltransf_5 Methyltransf_7 Methyltransf_8 Methyltransf_9 Methyltransf_PK MethyltransfD12 MetW Mg-por_mtran_C MOLO1 Mqo MT-A70 MTS Mur_ligase N2227 N6-adenineMlase N6_Mtase N6_N4_Mtase NAD_binding_10 NAD_binding_2 NAD_binding_3 NAD_binding_4 NAD_binding_5 NAD_binding_7 NAD_binding_8 NAD_binding_9 NAD_Gly3P_dh_N NAS NmrA NNMT_PNMT_TEMT NodS OCD_Mu_crystall Orbi_VP4 PALP PARP_regulatory PCMT PDH PglD_N Polysacc_syn_2C Polysacc_synt_2 Pox_MCEL Pox_mRNA-cap Prenylcys_lyase PrmA PRMT5 Pyr_redox Pyr_redox_2 Pyr_redox_3 Reovirus_L2 RmlD_sub_bind Rossmann-like rRNA_methylase RrnaAD Rsm22 RsmJ Sacchrp_dh_NADP SAM_MT SE Semialdhyde_dh Shikimate_DH Spermine_synth TehB THF_DHG_CYH_C Thi4 ThiF TPM_phosphatase TPMT TrkA_N TRM TRM13 TrmK tRNA_U5-meth_tr Trp_halogenase TylF Ubie_methyltran UDPG_MGDP_dh_N UPF0020 UPF0146 Urocanase V_cholerae_RfbT XdhC_C YjeF_N

Alignments

We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets and the UniProtKB sequence database. More...

View options

We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(86)
Full
(113450)
Representative proteomes UniProt
(403384)
RP15
(11923)
RP35
(46893)
RP55
(101796)
RP75
(175725)
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PP/heatmap 1            

1Cannot generate PP/Heatmap alignments for seeds; no PP data available

Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(86)
Full
(113450)
Representative proteomes UniProt
(403384)
RP15
(11923)
RP35
(46893)
RP55
(101796)
RP75
(175725)
Alignment:
Format:
Order:
Sequence:
Gaps:
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Download options

We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(86)
Full
(113450)
Representative proteomes UniProt
(403384)
RP15
(11923)
RP35
(46893)
RP55
(101796)
RP75
(175725)
Raw Stockholm Download   Download   Download   Download   Download   Download    
Gzipped Download   Download   Download   Download   Download   Download    

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

HMM logo

HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...

Trees

This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.

Note: You can also download the data file for the tree.

Curation and family details

This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.

Curation View help on the curation process

Seed source: Prosite
Previous IDs: adh_zinc;
Type: Domain
Sequence Ontology: SO:0000417
Author: Sonnhammer ELL
Number in seed: 86
Number in full: 113450
Average length of the domain: 128.00 aa
Average identity of full alignment: 20 %
Average coverage of the sequence by the domain: 31.03 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 31.8 31.8
Trusted cut-off 31.8 31.8
Noise cut-off 31.7 31.7
Model length: 130
Family (HMM) version: 28
Download: download the raw HMM for this family

Species distribution

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Viroids Viroids Unclassified sequence Unclassified sequence

Selections

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the ADH_zinc_N domain has been found. There are 871 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.

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AlphaFold Structure Predictions

The list of proteins below match this family and have AlphaFold predicted structures. Click on the protein accession to view the predicted structure.

Protein Predicted structure External Information
A0A089QRB9 View 3D Structure Click here
A0A0P0VRW1 View 3D Structure Click here
A0A0P0WKK9 View 3D Structure Click here
A0A0P0XBM6 View 3D Structure Click here
A0A0P0Y895 View 3D Structure Click here
A0A0R0EAL6 View 3D Structure Click here
A0A0R0F139 View 3D Structure Click here
A0A0R0FW40 View 3D Structure Click here
A0A0R0GTU4 View 3D Structure Click here
A0A0R0H054 View 3D Structure Click here
A0A0R0HA20 View 3D Structure Click here
A0A0R0I0M3 View 3D Structure Click here
A0A0R0IEK0 View 3D Structure Click here
A0A0R0IIS7 View 3D Structure Click here
A0A0R0ITG0 View 3D Structure Click here
A0A0R0IWD7 View 3D Structure Click here
A0A0R0J9C8 View 3D Structure Click here
A0A0R0JES7 View 3D Structure Click here
A0A0R0JL19 View 3D Structure Click here
A0A0R0KKL1 View 3D Structure Click here
A0A0R0KSS1 View 3D Structure Click here
A0A0R4J2H4 View 3D Structure Click here
A0A0R4J2R3 View 3D Structure Click here
A0A0R4J364 View 3D Structure Click here
A0A0R4J4D2 View 3D Structure Click here
A0A0R4J4U4 View 3D Structure Click here
A0A0R4J5U6 View 3D Structure Click here
A0A1D5NSP9 View 3D Structure Click here
A0A1D5RMB0 View 3D Structure Click here
A0A1D6DYL5 View 3D Structure Click here
A0A1D6HNQ2 View 3D Structure Click here
A0A1D6HP90 View 3D Structure Click here
A0A1D6I3Z8 View 3D Structure Click here
A0A1D6I5W8 View 3D Structure Click here
A0A1D6I5X9 View 3D Structure Click here
A0A1D6JJP0 View 3D Structure Click here
A0A1D6JR64 View 3D Structure Click here
A0A1D6JR65 View 3D Structure Click here
A0A1D6KC47 View 3D Structure Click here
A0A1D6KC48 View 3D Structure Click here
A0A1D6KL30 View 3D Structure Click here
A0A1D6LDQ8 View 3D Structure Click here
A0A1D6LL83 View 3D Structure Click here
A0A1D6N563 View 3D Structure Click here
A0A1D6QBR6 View 3D Structure Click here
A0A1D8PDC5 View 3D Structure Click here
A0A1D8PH64 View 3D Structure Click here
A0A1D8PH67 View 3D Structure Click here
A0A1D8PIM0 View 3D Structure Click here
A0A1D8PIW1 View 3D Structure Click here
A0A1D8PMM8 View 3D Structure Click here
A0A1D8PNH7 View 3D Structure Click here
A0A1D8PP43 View 3D Structure Click here
A0A1D8PQE3 View 3D Structure Click here
A0A1D8PS45 View 3D Structure Click here
A0A1D8PSE7 View 3D Structure Click here
A0A1D8PSF7 View 3D Structure Click here
A0A1D8PSZ0 View 3D Structure Click here
A0A1D8PU61 View 3D Structure Click here
A0A1D8PUB4 View 3D Structure Click here
A0A286Y901 View 3D Structure Click here
A0A286YBD8 View 3D Structure Click here
A0A2R8RPQ9 View 3D Structure Click here
A1L4Y2 View 3D Structure Click here
A1L4Y4 View 3D Structure Click here
A4HSH5 View 3D Structure Click here
A4HUG8 View 3D Structure Click here
A4HUG9 View 3D Structure Click here
A4HVK0 View 3D Structure Click here
A4I076 View 3D Structure Click here
A4I8R5 View 3D Structure Click here
A4IE56 View 3D Structure Click here
A5PN39 View 3D Structure Click here
B0BNC9 View 3D Structure Click here
B4FAJ0 View 3D Structure Click here
B4FBW5 View 3D Structure Click here
B4FJW4 View 3D Structure Click here
B4FPE6 View 3D Structure Click here
B4FR97 View 3D Structure Click here
B4G1G0 View 3D Structure Click here
B6SUD1 View 3D Structure Click here
B6U7D8 View 3D Structure Click here
C0PGX3 View 3D Structure Click here
C0PJR9 View 3D Structure Click here
C6T942 View 3D Structure Click here
C6TB56 View 3D Structure Click here
C6THI3 View 3D Structure Click here
C6TID4 View 3D Structure Click here
C6TIQ5 View 3D Structure Click here
C6TKH5 View 3D Structure Click here
D3ZT84 View 3D Structure Click here
D4A264 View 3D Structure Click here
E7EYZ5 View 3D Structure Click here
E7F5V3 View 3D Structure Click here
E9AG46 View 3D Structure Click here
E9Q5Z6 View 3D Structure Click here
F1Q713 View 3D Structure Click here
F1QP54 View 3D Structure Click here
F4I3C3 View 3D Structure Click here
F4IBH8 View 3D Structure Click here
F4KFK3 View 3D Structure Click here
I1J7B3 View 3D Structure Click here
I1J7B4 View 3D Structure Click here
I1JEV3 View 3D Structure Click here
I1JIQ4 View 3D Structure Click here
I1JMF6 View 3D Structure Click here
I1JMF7 View 3D Structure Click here
I1JMF8 View 3D Structure Click here
I1JP95 View 3D Structure Click here
I1JY29 View 3D Structure Click here
I1JYD9 View 3D Structure Click here
I1K548 View 3D Structure Click here
I1KB52 View 3D Structure Click here
I1KKE1 View 3D Structure Click here
I1L3S5 View 3D Structure Click here
I1L4T5 View 3D Structure Click here
I1L8I0 View 3D Structure Click here
I1LP48 View 3D Structure Click here
I1LU49 View 3D Structure Click here
I1LVH0 View 3D Structure Click here
I1M4P9 View 3D Structure Click here
I1M7A9 View 3D Structure Click here
I1MA91 View 3D Structure Click here
I1MAE6 View 3D Structure Click here
I1MC17 View 3D Structure Click here
I1ME21 View 3D Structure Click here
I1MQ30 View 3D Structure Click here
I1MY52 View 3D Structure Click here
I1N2X1 View 3D Structure Click here
I1N9X0 View 3D Structure Click here
I1NE10 View 3D Structure Click here
I6Y231 View 3D Structure Click here
K7KWL3 View 3D Structure Click here
K7L2E0 View 3D Structure Click here
K7LAX2 View 3D Structure Click here
K7M2W5 View 3D Structure Click here
K7TH21 View 3D Structure Click here
K7TK74 View 3D Structure Click here
K7UAQ8 View 3D Structure Click here
K7UXK5 View 3D Structure Click here
K7VET5 View 3D Structure Click here
K7VVX9 View 3D Structure Click here
L7N6B3 View 3D Structure Click here
M9PB21 View 3D Structure Click here
O07721 View 3D Structure Click here
O07737 View 3D Structure Click here
O24562 View 3D Structure Click here
O42909 View 3D Structure Click here
O45496 View 3D Structure Click here
O45687 View 3D Structure Click here
O45903 View 3D Structure Click here
O49482 View 3D Structure Click here
O53146 View 3D Structure Click here
O53533 View 3D Structure Click here
O53901 View 3D Structure Click here
O65423 View 3D Structure Click here
O65621 View 3D Structure Click here
O65933 View 3D Structure Click here
O69693 View 3D Structure Click here
O74489 View 3D Structure Click here
O74540 View 3D Structure Click here
O74822 View 3D Structure Click here
O94038 View 3D Structure Click here
O94564 View 3D Structure Click here
O96299 View 3D Structure Click here
O97479 View 3D Structure Click here
P00325 View 3D Structure Click here
P00326 View 3D Structure Click here
P00329 View 3D Structure Click here
P00330 View 3D Structure Click here
P00331 View 3D Structure Click here
P00332 View 3D Structure Click here
P00333 View 3D Structure Click here
P04707 View 3D Structure Click here
P06525 View 3D Structure Click here
P06757 View 3D Structure Click here
P07246 View 3D Structure Click here
P07327 View 3D Structure Click here
P07913 View 3D Structure Click here
P08319 View 3D Structure Click here
P0A9S3 View 3D Structure Click here
P11766 View 3D Structure Click here
P12711 View 3D Structure Click here
P12785 View 3D Structure Click here
P19096 View 3D Structure Click here
P25377 View 3D Structure Click here
P25437 View 3D Structure Click here
P25608 View 3D Structure Click here
P26646 View 3D Structure Click here
P27250 View 3D Structure Click here
P27867 View 3D Structure Click here
P28304 View 3D Structure Click here
P28332 View 3D Structure Click here
P28474 View 3D Structure Click here
P32771 View 3D Structure Click here
P35497 View 3D Structure Click here
P36624 View 3D Structure Click here
P38071 View 3D Structure Click here
P38105 View 3D Structure Click here
P38113 View 3D Structure Click here
P38230 View 3D Structure Click here
P39346 View 3D Structure Click here
P39400 View 3D Structure Click here
P39451 View 3D Structure Click here
P39713 View 3D Structure Click here
P39714 View 3D Structure Click here
P40394 View 3D Structure Click here
P41682 View 3D Structure Click here
P42734 View 3D Structure Click here
P46415 View 3D Structure Click here
P47199 View 3D Structure Click here
P48523 View 3D Structure Click here
P49327 View 3D Structure Click here
P52048 View 3D Structure Click here
P53912 View 3D Structure Click here
P54007 View 3D Structure Click here
P72043 View 3D Structure Click here
P75691 View 3D Structure Click here
P76043 View 3D Structure Click here
P76113 View 3D Structure Click here
P77280 View 3D Structure Click here
P77316 View 3D Structure Click here
P77360 View 3D Structure Click here
P77539 View 3D Structure Click here
P78870 View 3D Structure Click here
P91871 View 3D Structure Click here
P93629 View 3D Structure Click here
P95185 View 3D Structure Click here
P96826 View 3D Structure Click here
P97584 View 3D Structure Click here
P9WQB9 View 3D Structure Click here
P9WQC3 View 3D Structure Click here
P9WQC5 View 3D Structure Click here
P9WQC7 View 3D Structure Click here
Q00796 View 3D Structure Click here
Q02971 View 3D Structure Click here
Q02972 View 3D Structure Click here
Q03102 View 3D Structure Click here
Q04894 View 3D Structure Click here
Q07786 View 3D Structure Click here
Q07993 View 3D Structure Click here
Q0DWH1 View 3D Structure Click here
Q0G840 View 3D Structure Click here
Q0ITW6 View 3D Structure Click here
Q0ITW7 View 3D Structure Click here
Q0J6T3 View 3D Structure Click here
Q0JA75 View 3D Structure Click here
Q0V7W6 View 3D Structure Click here
Q10488 View 3D Structure Click here
Q10A46 View 3D Structure Click here
Q10PS6 View 3D Structure Click here
Q10QN9 View 3D Structure Click here
Q10QP0 View 3D Structure Click here
Q14914 View 3D Structure Click here
Q17334 View 3D Structure Click here
Q17335 View 3D Structure Click here
Q21702 View 3D Structure Click here
Q21703 View 3D Structure Click here
Q23624 View 3D Structure Click here
Q2FVQ0 View 3D Structure Click here
Q2FW62 View 3D Structure Click here
Q2G0G1 View 3D Structure Click here
Q2G1B9 View 3D Structure Click here
Q2G1C4 View 3D Structure Click here
Q2G2C5 View 3D Structure Click here
Q2G2C7 View 3D Structure Click here
Q2G2D7 View 3D Structure Click here
Q2QVJ5 View 3D Structure Click here
Q2QVJ6 View 3D Structure Click here
Q2QVJ8 View 3D Structure Click here
Q2QVK7 View 3D Structure Click here
Q2R114 View 3D Structure Click here
Q2R8Z5 View 3D Structure Click here
Q336S6 View 3D Structure Click here
Q337Y2 View 3D Structure Click here
Q39172 View 3D Structure Click here
Q39173 View 3D Structure Click here
Q3UNZ8 View 3D Structure Click here
Q43264 View 3D Structure Click here
Q4CNS6 View 3D Structure Click here
Q4CSB2 View 3D Structure Click here
Q4CXB5 View 3D Structure Click here
Q4DCU4 View 3D Structure Click here
Q4DEF3 View 3D Structure Click here
Q4DFP0 View 3D Structure Click here
Q4DJM7 View 3D Structure Click here
Q53FA7 View 3D Structure Click here
Q53LC7 View 3D Structure Click here
Q54LY2 View 3D Structure Click here
Q54LY4 View 3D Structure Click here
Q54TC2 View 3D Structure Click here
Q54UL7 View 3D Structure Click here
Q54YT4 View 3D Structure Click here
Q556G1 View 3D Structure Click here
Q556P4 View 3D Structure Click here
Q55AJ2 View 3D Structure Click here
Q55GE3 View 3D Structure Click here
Q59Z38 View 3D Structure Click here
Q59ZH5 View 3D Structure Click here
Q5A1B1 View 3D Structure Click here
Q5AC33 View 3D Structure Click here
Q5ANC5 View 3D Structure Click here
Q5BK81 View 3D Structure Click here
Q5XI95 View 3D Structure Click here
Q64437 View 3D Structure Click here
Q64442 View 3D Structure Click here
Q64563 View 3D Structure Click here
Q67J16 View 3D Structure Click here
Q69XJ5 View 3D Structure Click here
Q6AYT0 View 3D Structure Click here
Q6ERW5 View 3D Structure Click here
Q6ERW7 View 3D Structure Click here
Q6ERW9 View 3D Structure Click here
Q6ERX1 View 3D Structure Click here
Q6GQN8 View 3D Structure Click here
Q6H5W1 View 3D Structure Click here
Q6K840 View 3D Structure Click here
Q6NXA6 View 3D Structure Click here
Q6NZZ1 View 3D Structure Click here
Q6P0S5 View 3D Structure Click here
Q6ZBH2 View 3D Structure Click here
Q6ZHS4 View 3D Structure Click here
Q75JD7 View 3D Structure Click here
Q75JT6 View 3D Structure Click here
Q75JW6 View 3D Structure Click here
Q7PLB8 View 3D Structure Click here
Q7T2J4 View 3D Structure Click here
Q7XUK3 View 3D Structure Click here
Q7XWU3 View 3D Structure Click here
Q869N7 View 3D Structure Click here
Q86AG4 View 3D Structure Click here
Q8BGC4 View 3D Structure Click here
Q8H859 View 3D Structure Click here
Q8LCU7 View 3D Structure Click here
Q8LEB2 View 3D Structure Click here
Q8LHA1 View 3D Structure Click here
Q8LPM0 View 3D Structure Click here
Q8MNM6 View 3D Structure Click here
Q8N4Q0 View 3D Structure Click here
Q8N8N7 View 3D Structure Click here
Q8S0M7 View 3D Structure Click here
Q8VDQ1 View 3D Structure Click here
Q8VZ49 View 3D Structure Click here
Q91YR9 View 3D Structure Click here
Q93Z72 View 3D Structure Click here
Q93ZM6 View 3D Structure Click here
Q96533 View 3D Structure Click here
Q9BV79 View 3D Structure Click here
Q9C0Y6 View 3D Structure Click here
Q9C677 View 3D Structure Click here
Q9CAI3 View 3D Structure Click here
Q9DCS3 View 3D Structure Click here
Q9FH04 View 3D Structure Click here
Q9FJ95 View 3D Structure Click here
Q9FKC9 View 3D Structure Click here
Q9FKD2 View 3D Structure Click here
Q9LFK5 View 3D Structure Click here
Q9LTB4 View 3D Structure Click here
Q9LXZ4 View 3D Structure Click here
Q9M9M7 View 3D Structure Click here
Q9P6I8 View 3D Structure Click here
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