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76  structures 4220  species 0  interactions 28124  sequences 199  architectures

Family: PTR2 (PF00854)

Summary: POT family

Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.

This is the Wikipedia entry entitled "Proton-dependent oligopeptide transporter". More...

Proton-dependent oligopeptide transporter Edit Wikipedia article

POT family
Identifiers
SymbolPTR2
PfamPF00854
InterProIPR000109
PROSITEPDOC00784
TCDB2.A.17
OPM superfamily15
OPM protein2xut

Proteins of the Proton-dependent Oligopeptide Transporter (POT) Family (also called the PTR (peptide transport) family) are found in animals, plants, yeast, archaea and both Gram-negative and Gram-positive bacteria, and are part of the major facilitator superfamily. The transport of peptides into cells is a well-documented biological phenomenon which is accomplished by specific, energy-dependent transporters found in a number of organisms as diverse as bacteria and humans. The proton-dependent oligopeptide transporter (PTR) family of proteins is distinct from the ABC-type peptide transporters and was uncovered by sequence analyses of a number of recently discovered peptide transport proteins.[1] These proteins that seem to be mainly involved in the intake of small peptides with the concomitant uptake of a proton.[2]

Function

While most members of the POT family catalyze peptide transport, one is a nitrate permease and one can transport histidine, as well as peptides. Some of the peptide transporters can also transport antibiotics. They function by proton symport, but the substrate:H+ stoichiometry is variable: the high-affinity rat PepT2 carrier catalyzes uptake of 2 and 3 H+ with neutral and anionic dipeptides, respectively, while the low affinity PepT1 carrier catalyzes uptake of one H+ per neutral peptide.[3][4]

Transport Reaction

The generalized transport reaction catalyzed by the proteins of the POT family is:

substrate (out) + H (out) → substrate (in) H+ (in)

Structure and Mechanism

The proteins are of about 450-600 amino acyl residues in length with the eukaryotic proteins in general being longer than the bacterial proteins. They exhibit 12 putative or established transmembrane α-helical spanners.

Pairs of salt bridge interactions between transmembrane helices work in tandem to orchestrate alternating access transport within the PTR family.[5] Key roles for residues conserved between bacterial and eukaryotic homologues suggest a conserved mechanism of peptide recognition and transport that in some cases has been subtly modified in individual species.

Subfamilies

Human proteins containing this domain

FP12591; PEPT1; PTR4; SLC15A1; SLC15A2; SLC15A3; SLC15A4; hPEPT1-RF;

References

  1. ^ Naider F, Becker JM, Steiner HY (1995). "The PTR family: a new group of peptide transporters". Mol. Microbiol. 16 (5): 825–834. doi:10.1111/j.1365-2958.1995.tb02310.x. PMID 7476181.
  2. ^ Skurray RA, Paulsen IT (1994). "The POT family of transport proteins". Trends Biochem. Sci. 19 (10): 404–404. doi:10.1016/0968-0004(94)90087-6. PMID 7817396.
  3. ^ Bucking, Carol; Schulte, Patricia M. (2012-04-01). "Environmental and nutritional regulation of expression and function of two peptide transporter (PepT1) isoforms in a euryhaline teleost". Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology. 161 (4): 379–387. doi:10.1016/j.cbpa.2011.12.008. ISSN 1531-4332. PMID 22227314.
  4. ^ Chen, Xing-Zhen (29 Jan 1999). "Stoichiometry and kinetics of the high-affinity H+-coupled peptide transporter PepT2". Journal of Biological Chemistry. 274 (5). doi:10.1074/jbc.274.5.2773. PMID 9915809.
  5. ^ Doki, Shintaro; Kato, Hideaki E.; Solcan, Nicolae; Iwaki, Masayo; Koyama, Michio; Hattori, Motoyuki; Iwase, Norihiko; Tsukazaki, Tomoya; Sugita, Yuji (2013-07-09). "Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT". Proceedings of the National Academy of Sciences of the United States of America. 110 (28): 11343–11348. doi:10.1073/pnas.1301079110. ISSN 1091-6490. PMC 3710879. PMID 23798427.

As of this edit, this article uses content from "2.A.17 The Proton-dependent Oligopeptide Transporter (POT/PTR) Family", which is licensed in a way that permits reuse under the Creative Commons Attribution-ShareAlike 3.0 Unported License, but not under the GFDL. All relevant terms must be followed.

This article incorporates text from the public domain Pfam and InterPro: IPR000109

This page is based on a Wikipedia article. The text is available under the Creative Commons Attribution/Share-Alike License.

This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.

POT family Provide feedback

The POT (proton-dependent oligopeptide transport) family all appear to be proton dependent transporters [1].

Literature references

  1. Paulsen IT, Skurray RA; , Trends Biochem Sci 1994;19:404-404.: The POT family of transport proteins. PUBMED:7817396 EPMC:7817396


Internal database links

External database links

This tab holds annotation information from the InterPro database.

InterPro entry IPR000109

The proton-dependent oligopeptide transporter (POT) family (also known as the peptide transport (PTR) family) is made up of a group of energy-dependent transporters found in organisms as diverse as bacteria and humans. The POT family of proteins is distinct from the ABC-type peptide transporters and was uncovered by sequence analyses of peptide transport proteins [ PUBMED:7476181 ]. They seem to be mainly involved in the intake of small peptides [ PUBMED:7817396 ]. However, some family members are nitrate permeases and others are involved in histidine transport [ PUBMED:17481610 ].

Gene Ontology

The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.

Domain organisation

Below is a listing of the unique domain organisations or architectures in which this domain is found. More...

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Pfam Clan

This family is a member of clan MFS (CL0015), which has the following description:

The major facilitator superfamily (MFS) is one of the two largest families of membrane transporters found on Earth [1]. It is present ubiquitously in bacteria, archaea, and eukarya and includes members that can function by solute uniport, solute/cation symport, solute/cation antiport and/or solute/solute antiport with inwardly and/or outwardly directed polarity [1]. All permeases of the MFS possess either 12 or 14 transmembrane helices [1].

The clan contains the following 23 members:

Acatn ATG22 BT1 Folate_carrier FPN1 LacY_symp MFS_1 MFS_1_like MFS_2 MFS_3 MFS_4 MFS_5 MFS_Mycoplasma Nodulin-like Nuc_H_symport Nucleoside_tran OATP PTR2 PUCC Sugar_tr TLC TRI12 UNC-93

Alignments

We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets and the UniProtKB sequence database. More...

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We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(21)
Full
(28124)
Representative proteomes UniProt
(70336)
RP15
(3067)
RP35
(12622)
RP55
(23928)
RP75
(36027)
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PP/heatmap 1            

1Cannot generate PP/Heatmap alignments for seeds; no PP data available

Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(21)
Full
(28124)
Representative proteomes UniProt
(70336)
RP15
(3067)
RP35
(12622)
RP55
(23928)
RP75
(36027)
Alignment:
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We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(21)
Full
(28124)
Representative proteomes UniProt
(70336)
RP15
(3067)
RP35
(12622)
RP55
(23928)
RP75
(36027)
Raw Stockholm Download   Download   Download   Download   Download   Download   Download  
Gzipped Download   Download   Download   Download   Download   Download   Download  

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

HMM logo

HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...

Trees

This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.

Note: You can also download the data file for the tree.

Curation and family details

This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.

Curation View help on the curation process

Seed source: Pfam-B_571 (release 3.0)
Previous IDs: none
Type: Family
Sequence Ontology: SO:0100021
Author: Bateman A
Number in seed: 21
Number in full: 28124
Average length of the domain: 320.70 aa
Average identity of full alignment: 20 %
Average coverage of the sequence by the domain: 70.58 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 21.9 21.9
Trusted cut-off 21.9 21.9
Noise cut-off 21.8 21.8
Model length: 397
Family (HMM) version: 23
Download: download the raw HMM for this family

Species distribution

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Archea Archea Eukaryota Eukaryota
Bacteria Bacteria Other sequences Other sequences
Viruses Viruses Unclassified Unclassified
Viroids Viroids Unclassified sequence Unclassified sequence

Selections

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the PTR2 domain has been found. There are 76 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.

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AlphaFold Structure Predictions

The list of proteins below match this family and have AlphaFold predicted structures. Click on the protein accession to view the predicted structure.

Protein Predicted structure External Information
A0A096SQP7 View 3D Structure Click here
A0A0B4J3J0 View 3D Structure Click here
A0A0N7KD56 View 3D Structure Click here
A0A0N7KG46 View 3D Structure Click here
A0A0N7KJ69 View 3D Structure Click here
A0A0N7KLU4 View 3D Structure Click here
A0A0N7KSS2 View 3D Structure Click here
A0A0N7KTT3 View 3D Structure Click here
A0A0P0V856 View 3D Structure Click here
A0A0P0VAW9 View 3D Structure Click here
A0A0P0VAX0 View 3D Structure Click here
A0A0P0VAY0 View 3D Structure Click here
A0A0P0VAZ6 View 3D Structure Click here
A0A0P0VB13 View 3D Structure Click here
A0A0P0VBU6 View 3D Structure Click here
A0A0P0VD41 View 3D Structure Click here
A0A0P0VJK5 View 3D Structure Click here
A0A0P0VV34 View 3D Structure Click here
A0A0P0VWV3 View 3D Structure Click here
A0A0P0WBS7 View 3D Structure Click here
A0A0P0WC91 View 3D Structure Click here
A0A0P0WE81 View 3D Structure Click here
A0A0P0WGM6 View 3D Structure Click here
A0A0P0WGM6 View 3D Structure Click here
A0A0P0WL01 View 3D Structure Click here
A0A0P0WML3 View 3D Structure Click here
A0A0P0WWG1 View 3D Structure Click here
A0A0P0X0M0 View 3D Structure Click here
A0A0P0X150 View 3D Structure Click here
A0A0P0X5F6 View 3D Structure Click here
A0A0P0XHZ8 View 3D Structure Click here
A0A0P0XHZ8 View 3D Structure Click here
A0A0P0XQX3 View 3D Structure Click here
A0A0P0XQY0 View 3D Structure Click here
A0A0P0XQZ1 View 3D Structure Click here
A0A0P0XR23 View 3D Structure Click here
A0A0P0Y1S1 View 3D Structure Click here
A0A0P0Y8I7 View 3D Structure Click here
A0A0R0ES35 View 3D Structure Click here
A0A0R0EVP0 View 3D Structure Click here
A0A0R0F7J1 View 3D Structure Click here
A0A0R0FKZ4 View 3D Structure Click here
A0A0R0FLU8 View 3D Structure Click here
A0A0R0FLU8 View 3D Structure Click here
A0A0R0FNN4 View 3D Structure Click here
A0A0R0FXV0 View 3D Structure Click here
A0A0R0HKR6 View 3D Structure Click here
A0A0R0I7K0 View 3D Structure Click here
A0A0R0J6B6 View 3D Structure Click here
A0A0R0J9Q7 View 3D Structure Click here
A0A0R0J9Q7 View 3D Structure Click here
A0A0R0JRL3 View 3D Structure Click here
A0A0R0JRL3 View 3D Structure Click here
A0A0R0JV07 View 3D Structure Click here
A0A0R0JV07 View 3D Structure Click here
A0A0R0JVS7 View 3D Structure Click here
A0A0R0JWX4 View 3D Structure Click here
A0A0R0K2W7 View 3D Structure Click here
A0A0R0KCS5 View 3D Structure Click here
A0A0R0KFH8 View 3D Structure Click here
A0A0R0KFU5 View 3D Structure Click here
A0A0R0L6H4 View 3D Structure Click here
A0A0R0LD87 View 3D Structure Click here
A0A0R0LDX7 View 3D Structure Click here
A0A0R0LFA4 View 3D Structure Click here
A0A0R4ICA5 View 3D Structure Click here
A0A0R4J2Z0 View 3D Structure Click here
A0A0R4J4E5 View 3D Structure Click here
A0A1D6DUZ1 View 3D Structure Click here
A0A1D6E7L3 View 3D Structure Click here
A0A1D6E9Z7 View 3D Structure Click here
A0A1D6EF27 View 3D Structure Click here
A0A1D6EGK3 View 3D Structure Click here
A0A1D6F128 View 3D Structure Click here
A0A1D6F541 View 3D Structure Click here
A0A1D6F5F9 View 3D Structure Click here
A0A1D6G6V9 View 3D Structure Click here
A0A1D6G7B3 View 3D Structure Click here
A0A1D6GE39 View 3D Structure Click here
A0A1D6HGH7 View 3D Structure Click here
A0A1D6HGS3 View 3D Structure Click here
A0A1D6HGS5 View 3D Structure Click here
A0A1D6HGS5 View 3D Structure Click here
A0A1D6HI85 View 3D Structure Click here
A0A1D6HI85 View 3D Structure Click here
A0A1D6HI85 View 3D Structure Click here
A0A1D6HKH8 View 3D Structure Click here
A0A1D6HWP2 View 3D Structure Click here
A0A1D6I2R4 View 3D Structure Click here
A0A1D6J2Q1 View 3D Structure Click here
A0A1D6J967 View 3D Structure Click here
A0A1D6JDG5 View 3D Structure Click here
A0A1D6JK18 View 3D Structure Click here
A0A1D6JVD8 View 3D Structure Click here
A0A1D6K8L2 View 3D Structure Click here
A0A1D6KAA7 View 3D Structure Click here
A0A1D6KB42 View 3D Structure Click here
A0A1D6KB43 View 3D Structure Click here
A0A1D6KGL5 View 3D Structure Click here
A0A1D6KGY4 View 3D Structure Click here
A0A1D6KIK5 View 3D Structure Click here
A0A1D6KTR5 View 3D Structure Click here
A0A1D6LA09 View 3D Structure Click here
A0A1D6LSL7 View 3D Structure Click here
A0A1D6LSL7 View 3D Structure Click here
A0A1D6M486 View 3D Structure Click here
A0A1D6M487 View 3D Structure Click here
A0A1D6M491 View 3D Structure Click here
A0A1D6M5J6 View 3D Structure Click here
A0A1D6M5J7 View 3D Structure Click here
A0A1D6MUP1 View 3D Structure Click here
A0A1D6N496 View 3D Structure Click here
A0A1D6N624 View 3D Structure Click here
A0A1D6N624 View 3D Structure Click here
A0A1D6N628 View 3D Structure Click here
A0A1D6N628 View 3D Structure Click here
A0A1D6N629 View 3D Structure Click here
A0A1D6NAZ1 View 3D Structure Click here
A0A1D6NC75 View 3D Structure Click here
A0A1D6NMX1 View 3D Structure Click here
A0A1D6NZT1 View 3D Structure Click here
A0A1D6NZT1 View 3D Structure Click here
A0A1D6P4D9 View 3D Structure Click here
A0A1D6PTX6 View 3D Structure Click here
A0A1D6Q1Q8 View 3D Structure Click here
A0A1D6QKM2 View 3D Structure Click here
A0A1D6QLL8 View 3D Structure Click here
A0A1D6QLL9 View 3D Structure Click here
A0A1D8PS27 View 3D Structure Click here
A0A368UIG4 View 3D Structure Click here
A0A368UIG4 View 3D Structure Click here
A4I8T7 View 3D Structure Click here
A6NIM6 View 3D Structure Click here
B0S6T2 View 3D Structure Click here
B0S6T2 View 3D Structure Click here
B4F8V4 View 3D Structure Click here
B4FAD0 View 3D Structure Click here
B4FBG4 View 3D Structure Click here
B4FCU8 View 3D Structure Click here
B4FQ14 View 3D Structure Click here
B4FWH5 View 3D Structure Click here
B6SWZ7 View 3D Structure Click here
B6SXJ7 View 3D Structure Click here
B6SXJ7 View 3D Structure Click here
B6UEH6 View 3D Structure Click here
B8A0B6 View 3D Structure Click here
B8A2W4 View 3D Structure Click here
B9FIM6 View 3D Structure Click here
C0HIH4 View 3D Structure Click here
C0P2K1 View 3D Structure Click here
C0P3B0 View 3D Structure Click here
C0PBR1 View 3D Structure Click here
C0PCC3 View 3D Structure Click here
C0PGF2 View 3D Structure Click here
C0PGF3 View 3D Structure Click here
C0PHE6 View 3D Structure Click here
C0PJ96 View 3D Structure Click here
C0PLZ2 View 3D Structure Click here
C4J1J8 View 3D Structure Click here
C4J5D4 View 3D Structure Click here
D3ZKX5 View 3D Structure Click here
F1QP47 View 3D Structure Click here
F1QP47 View 3D Structure Click here
I1J5J6 View 3D Structure Click here
I1J5K4 View 3D Structure Click here
I1J714 View 3D Structure Click here
I1J9K8 View 3D Structure Click here
I1J9X0 View 3D Structure Click here
I1JB65 View 3D Structure Click here
I1JBR6 View 3D Structure Click here
I1JBS2 View 3D Structure Click here
I1JHA8 View 3D Structure Click here
I1JIK5 View 3D Structure Click here
I1JN13 View 3D Structure Click here
I1JP63 View 3D Structure Click here
I1JR08 View 3D Structure Click here
I1JTG2 View 3D Structure Click here
I1JUU4 View 3D Structure Click here
I1JYA0 View 3D Structure Click here
I1JZS8 View 3D Structure Click here
I1JZT2 View 3D Structure Click here
I1JZT4 View 3D Structure Click here
I1K116 View 3D Structure Click here
I1K3A6 View 3D Structure Click here
I1K3A7 View 3D Structure Click here
I1K439 View 3D Structure Click here
I1K5W3 View 3D Structure Click here
I1K7W4 View 3D Structure Click here
I1KBA5 View 3D Structure Click here
I1KGM2 View 3D Structure Click here
I1KGM3 View 3D Structure Click here
I1KK49 View 3D Structure Click here
I1KKB0 View 3D Structure Click here
I1KNR6 View 3D Structure Click here
I1KRN5 View 3D Structure Click here
I1KSJ0 View 3D Structure Click here
I1KTG7 View 3D Structure Click here
I1KV57 View 3D Structure Click here
I1KV58 View 3D Structure Click here
I1KXP8 View 3D Structure Click here
I1KXP9 View 3D Structure Click here
I1L5X2 View 3D Structure Click here
I1L7G2 View 3D Structure Click here
I1LAX9 View 3D Structure Click here
I1LC89 View 3D Structure Click here
I1LLE9 View 3D Structure Click here
I1LMK2 View 3D Structure Click here
I1LMK4 View 3D Structure Click here
I1LMK6 View 3D Structure Click here
I1LMX4 View 3D Structure Click here
I1LNN9 View 3D Structure Click here
I1LT88 View 3D Structure Click here
I1LWF7 View 3D Structure Click here
I1LYD4 View 3D Structure Click here
I1LZZ3 View 3D Structure Click here
I1M0T0 View 3D Structure Click here
I1M4P2 View 3D Structure Click here
I1M7G1 View 3D Structure Click here
I1M9V7 View 3D Structure Click here
I1MB88 View 3D Structure Click here
I1MCR9 View 3D Structure Click here
I1MIR8 View 3D Structure Click here
I1MQT4 View 3D Structure Click here
I1MQT4 View 3D Structure Click here
I1MS09 View 3D Structure Click here
I1MTP1 View 3D Structure Click here
I1MTP9 View 3D Structure Click here
I1MUY7 View 3D Structure Click here
I1MVD0 View 3D Structure Click here
I1MW80 View 3D Structure Click here
I1MYX1 View 3D Structure Click here
I1MZ85 View 3D Structure Click here
I1MZ86 View 3D Structure Click here
I1MZ87 View 3D Structure Click here
I1N192 View 3D Structure Click here
I1N194 View 3D Structure Click here
I1N195 View 3D Structure Click here
I1N2N5 View 3D Structure Click here
I1N2N8 View 3D Structure Click here
I1N4D9 View 3D Structure Click here
I1N4E0 View 3D Structure Click here
I1N5E5 View 3D Structure Click here
I1N5Z2 View 3D Structure Click here
I1N8N3 View 3D Structure Click here
I1N9T4 View 3D Structure Click here
I1NET2 View 3D Structure Click here
I1NI63 View 3D Structure Click here
K7K2V2 View 3D Structure Click here
K7KD86 View 3D Structure Click here
K7KEL8 View 3D Structure Click here
K7KML5 View 3D Structure Click here
K7L4S1 View 3D Structure Click here
K7L8I4 View 3D Structure Click here
K7L8I5 View 3D Structure Click here
K7LAL6 View 3D Structure Click here
K7LFQ7 View 3D Structure Click here
K7LGQ8 View 3D Structure Click here
K7LN02 View 3D Structure Click here
K7LRM6 View 3D Structure Click here
K7LUB1 View 3D Structure Click here
K7M170 View 3D Structure Click here
K7M908 View 3D Structure Click here
K7MKT8 View 3D Structure Click here
K7MQX8 View 3D Structure Click here
K7MVL6 View 3D Structure Click here
K7MYR0 View 3D Structure Click here
K7N5I1 View 3D Structure Click here
K7THW9 View 3D Structure Click here
K7U7W3 View 3D Structure Click here
K7ULK6 View 3D Structure Click here
K7UYF4 View 3D Structure Click here
K7VN18 View 3D Structure Click here
O01840 View 3D Structure Click here
O01840 View 3D Structure Click here
O09014 View 3D Structure Click here
O80436 View 3D Structure Click here
P0CI03 View 3D Structure Click here
P32901 View 3D Structure Click here
P36837 View 3D Structure Click here
P39276 View 3D Structure Click here
P46032 View 3D Structure Click here
P46059 View 3D Structure Click here
P46059 View 3D Structure Click here
P51574 View 3D Structure Click here
P51574 View 3D Structure Click here
P75742 View 3D Structure Click here
P77304 View 3D Structure Click here
P91679 View 3D Structure Click here
P91679 View 3D Structure Click here
Q05085 View 3D Structure Click here
Q0DI75 View 3D Structure Click here
Q0DI76 View 3D Structure Click here
Q0DTN6 View 3D Structure Click here
Q0ILL8 View 3D Structure Click here
Q0IPA1 View 3D Structure Click here
Q0IZB5 View 3D Structure Click here
Q0IZB5 View 3D Structure Click here
Q0J7Y1 View 3D Structure Click here
Q0J9C7 View 3D Structure Click here
Q0JAI6 View 3D Structure Click here
Q0JHB8 View 3D Structure Click here
Q0JHC1 View 3D Structure Click here
Q0JHC3 View 3D Structure Click here
Q0JHC3 View 3D Structure Click here
Q0WP01 View 3D Structure Click here
Q0WSZ6 View 3D Structure Click here
Q10PF8 View 3D Structure Click here
Q10S13 View 3D Structure Click here
Q10T28 View 3D Structure Click here
Q16348 View 3D Structure Click here
Q16348 View 3D Structure Click here
Q17758 View 3D Structure Click here
Q17758 View 3D Structure Click here
Q21219 View 3D Structure Click here
Q21219 View 3D Structure Click here
Q2G082 View 3D Structure Click here
Q2QLL1 View 3D Structure Click here
Q2R726 View 3D Structure Click here
Q2R733 View 3D Structure Click here
Q336T8 View 3D Structure Click here
Q337L5 View 3D Structure Click here
Q339C7 View 3D Structure Click here
Q33BF9 View 3D Structure Click here
Q3E8X3 View 3D Structure Click here
Q3E9B5 View 3D Structure Click here
Q4DIV8 View 3D Structure Click here
Q4DR86 View 3D Structure Click here
Q53JI5 View 3D Structure Click here
Q53K47 View 3D Structure Click here
Q559I6 View 3D Structure Click here
Q559N7 View 3D Structure Click here
Q55G06 View 3D Structure Click here
Q56XQ6 View 3D Structure Click here
Q59ST2 View 3D Structure Click here
Q5KQF1 View 3D Structure Click here
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