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459  structures 2680  species 0  interactions 45881  sequences 1321  architectures

Family: SET (PF00856)

Summary: SET domain

Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.

This is the Wikipedia entry entitled "SET domain". More...

This page is based on a Wikipedia article. The text is available under the Creative Commons Attribution/Share-Alike License.

This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.

SET domain Provide feedback

SET domains are protein lysine methyltransferase enzymes. SET domains appear to be protein-protein interaction domains. It has been demonstrated that SET domains mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases) [2]. A subset of SET domains have been called PR domains. These domains are divergent in sequence from other SET domains, but also appear to mediate protein-protein interaction [3]. The SET domain consists of two regions known as SET-N and SET-C. SET-C forms an unusual and conserved knot-like structure of probably functional importance. Additionally to SET-N and SET-C, an insert region (SET-I) and flanking regions of high structural variability form part of the overall structure [5].

Literature references

  1. Tripoulas N, LaJeunesse D, Gildea J, Shearn A; , Genetics 1996;143:913-928.: The Drosophila ash1 gene product, which is localized at specific sites on polytene chromosomes, contains a SET domain and a PHD finger. PUBMED:8725238 EPMC:8725238

  2. Cui X, De Vivo I, Slany R, Miyamoto A, Firestein R, Cleary ML; , Nat Genet 1998;18:331-337.: Association of SET domain and myotubularin-related proteins modulates growth control. PUBMED:9537414 EPMC:9537414

  3. Huang S, Shao G, Liu L; , J Biol Chem 1998;273:15933-15939.: The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression. PUBMED:9632640 EPMC:9632640

  4. Min J, Zhang X, Cheng X, Grewal SI, Xu RM; , Nat Struct Biol 2002;0:0-0.: Structure of the SET domain histone lysine methyltransferase Clr4. PUBMED:12389037 EPMC:12389037

  5. Marmorstein R; , Trends Biochem Sci 2003;28:59-62.: Structure of SET domain proteins: a new twist on histone methylation. PUBMED:12575990 EPMC:12575990


Internal database links

External database links

This tab holds annotation information from the InterPro database.

InterPro entry IPR001214

The SET domain is a 130 to 140 amino acid, evolutionary well conserved sequence motif that was initially characterised in the Drosophila proteins Su(var)3-9, Enhancer-of-zeste and Trithorax. In addition to these chromosomal proteins modulating gene activities and/or chromatin structure, the SET domain is found in proteins of diverse functions ranging from yeast to mammals, but also including some bacteria and viruses [ PUBMED:9487389 , PUBMED:10949293 ].

The SET domains of mammalian SUV39H1 and 2 and fission yeast clr4 have been shown to be necessary for the methylation of lysine-9 in the histone H3 N terminus [ PUBMED:10949293 ]. However, this histone methyltransferase (HMTase) activity is probably restricted to a subset of SET domain proteins as it requires the combination of the SET domain with the adjacent cysteine-rich regions, one located N-terminally (pre-SET) and the other posterior to the SET domain (post-SET). Post- and pre- SET regions seem then to play a crucial role when it comes to substrate recognition and enzymatic activity [ PUBMED:12826405 , PUBMED:12372294 ].

The structure of the SET domain and the two adjacent regions pre-SET and post-SET have been solved [ PUBMED:12372305 , PUBMED:12372304 , PUBMED:12372303 ]. The SET structure is all beta, but consists only in sets of few short strands composing no more than a couple of small sheets. Consequently the SET structure is mostly defined by turns and loops. An unusual feature is that the SET core is made up of two discontinual segments of the primary sequence forming an approximate L shape [ PUBMED:9632640 , PUBMED:12826405 , PUBMED:12372294 ]. Two of the most conserved motifs in the SET domain are constituted by (1) a stretch at the C-terminal containing a strictly conserved tyrosine residue and (2) a preceding loop inside which the C-terminal segment passes forming a knot-like structure, but not quite a true knot. These two regions have been proven to be essential for SAM binding and catalysis, particularly the invariant tyrosine where in all likelihood catalysis takes place [ PUBMED:12826405 , PUBMED:12372294 ].

Gene Ontology

The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.

Domain organisation

Below is a listing of the unique domain organisations or architectures in which this domain is found. More...

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Alignments

We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets and the UniProtKB sequence database. More...

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We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(257)
Full
(45881)
Representative proteomes UniProt
(95008)
RP15
(8180)
RP35
(21375)
RP55
(37982)
RP75
(51833)
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PP/heatmap 1            

1Cannot generate PP/Heatmap alignments for seeds; no PP data available

Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(257)
Full
(45881)
Representative proteomes UniProt
(95008)
RP15
(8180)
RP35
(21375)
RP55
(37982)
RP75
(51833)
Alignment:
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We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(257)
Full
(45881)
Representative proteomes UniProt
(95008)
RP15
(8180)
RP35
(21375)
RP55
(37982)
RP75
(51833)
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Gzipped Download   Download   Download   Download   Download   Download   Download  

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

HMM logo

HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...

Trees

This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.

Note: You can also download the data file for the tree.

Curation and family details

This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.

Curation View help on the curation process

Seed source: [1]
Previous IDs: none
Type: Family
Sequence Ontology: SO:0100021
Author: Bateman A , Huang S
Number in seed: 257
Number in full: 45881
Average length of the domain: 160.30 aa
Average identity of full alignment: 19 %
Average coverage of the sequence by the domain: 19.56 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null --hand HMM SEED
search method: hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 22.4 22.4
Trusted cut-off 22.4 22.4
Noise cut-off 22.3 22.3
Model length: 169
Family (HMM) version: 30
Download: download the raw HMM for this family

Species distribution

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the SET domain has been found. There are 459 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.

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AlphaFold Structure Predictions

The list of proteins below match this family and have AlphaFold predicted structures. Click on the protein accession to view the predicted structure.

Protein Predicted structure External Information
A0A096MJU6 View 3D Structure Click here
A0A0G2JTW4 View 3D Structure Click here
A0A0G2JW37 View 3D Structure Click here
A0A0G2JWF0 View 3D Structure Click here
A0A0G2K001 View 3D Structure Click here
A0A0G2K5A7 View 3D Structure Click here
A0A0G2K6T6 View 3D Structure Click here
A0A0G2K889 View 3D Structure Click here
A0A0G2KB10 View 3D Structure Click here
A0A0P0V8S0 View 3D Structure Click here
A0A0P0VDF3 View 3D Structure Click here
A0A0P0VDJ3 View 3D Structure Click here
A0A0P0VE60 View 3D Structure Click here
A0A0P0VK92 View 3D Structure Click here
A0A0P0WFA2 View 3D Structure Click here
A0A0P0XCN3 View 3D Structure Click here
A0A0P0XDC9 View 3D Structure Click here
A0A0P0XQ57 View 3D Structure Click here
A0A0P0XYC1 View 3D Structure Click here
A0A0P0Y6F9 View 3D Structure Click here
A0A0R0EIG0 View 3D Structure Click here
A0A0R0ELD1 View 3D Structure Click here
A0A0R0EM36 View 3D Structure Click here
A0A0R0EQU1 View 3D Structure Click here
A0A0R0ET93 View 3D Structure Click here
A0A0R0EZ91 View 3D Structure Click here
A0A0R0FUI7 View 3D Structure Click here
A0A0R0G0Z4 View 3D Structure Click here
A0A0R0GH45 View 3D Structure Click here
A0A0R0GL68 View 3D Structure Click here
A0A0R0GZF1 View 3D Structure Click here
A0A0R0HD21 View 3D Structure Click here
A0A0R0I0W2 View 3D Structure Click here
A0A0R0I2D0 View 3D Structure Click here
A0A0R0I3Y4 View 3D Structure Click here
A0A0R0I6N1 View 3D Structure Click here
A0A0R0IGL3 View 3D Structure Click here
A0A0R0JEA7 View 3D Structure Click here
A0A0R0JKQ3 View 3D Structure Click here
A0A0R0KTU7 View 3D Structure Click here
A0A0R0LAZ3 View 3D Structure Click here
A0A0R4IMZ7 View 3D Structure Click here
A0A163UT06 View 3D Structure Click here
A0A1D6DXJ5 View 3D Structure Click here
A0A1D6E5H7 View 3D Structure Click here
A0A1D6EMN1 View 3D Structure Click here
A0A1D6EPB3 View 3D Structure Click here
A0A1D6EQ37 View 3D Structure Click here
A0A1D6EV07 View 3D Structure Click here
A0A1D6EZN1 View 3D Structure Click here
A0A1D6FGS6 View 3D Structure Click here
A0A1D6FSK8 View 3D Structure Click here
A0A1D6G0P9 View 3D Structure Click here
A0A1D6G529 View 3D Structure Click here
A0A1D6GJT5 View 3D Structure Click here
A0A1D6HAE6 View 3D Structure Click here
A0A1D6HHQ4 View 3D Structure Click here
A0A1D6HW59 View 3D Structure Click here
A0A1D6HY77 View 3D Structure Click here
A0A1D6I0U5 View 3D Structure Click here
A0A1D6I1R1 View 3D Structure Click here
A0A1D6IAB0 View 3D Structure Click here
A0A1D6ISR3 View 3D Structure Click here
A0A1D6IY74 View 3D Structure Click here
A0A1D6IYK8 View 3D Structure Click here
A0A1D6IZ65 View 3D Structure Click here
A0A1D6JMZ2 View 3D Structure Click here
A0A1D6KLQ2 View 3D Structure Click here
A0A1D6KLS4 View 3D Structure Click here
A0A1D6KNR1 View 3D Structure Click here
A0A1D6KQ57 View 3D Structure Click here
A0A1D6KR74 View 3D Structure Click here
A0A1D6LK95 View 3D Structure Click here
A0A1D6M742 View 3D Structure Click here
A0A1D6MTR0 View 3D Structure Click here
A0A1D6N2J4 View 3D Structure Click here
A0A1D6N963 View 3D Structure Click here
A0A1D6NH18 View 3D Structure Click here
A0A1D6PYI9 View 3D Structure Click here
A0A1D6Q4P2 View 3D Structure Click here
A0A1D6Q562 View 3D Structure Click here
A0A1D6Q8W2 View 3D Structure Click here
A0A1D6Q9U3 View 3D Structure Click here
A0A1D8PNN9 View 3D Structure Click here
A0A1D8PP54 View 3D Structure Click here
A0A1D8PT54 View 3D Structure Click here
A0A1D8PTX3 View 3D Structure Click here
A0A1I9LQY7 View 3D Structure Click here
A0A2R8PXU7 View 3D Structure Click here
A0A2R8PYC7 View 3D Structure Click here
A0A2R8Q5R0 View 3D Structure Click here
A0A2R8QCU6 View 3D Structure Click here
A0A2R8QFE1 View 3D Structure Click here
A0A2R8QJZ9 View 3D Structure Click here
A0A2R8QTI0 View 3D Structure Click here
A0A368UGE2 View 3D Structure Click here
A0A368UGG2 View 3D Structure Click here
A0A368UH13 View 3D Structure Click here
A1Z7W1 View 3D Structure Click here
A1Z8L3 View 3D Structure Click here
A1ZAP0 View 3D Structure Click here
A2A7B5 View 3D Structure Click here
A2AGX3 View 3D Structure Click here
A4HSZ2 View 3D Structure Click here
A4HTM8 View 3D Structure Click here
A4HU63 View 3D Structure Click here
A4HWL1 View 3D Structure Click here
A4HXZ6 View 3D Structure Click here
A4I091 View 3D Structure Click here
A4I0D0 View 3D Structure Click here
A4I0D3 View 3D Structure Click here
A4I1M6 View 3D Structure Click here
A4I2H5 View 3D Structure Click here
A4I360 View 3D Structure Click here
A4I5R0 View 3D Structure Click here
A4I6N0 View 3D Structure Click here
A4I8R4 View 3D Structure Click here
A4I9Q7 View 3D Structure Click here
A4IBZ5 View 3D Structure Click here
A4IBZ5 View 3D Structure Click here
A4IBZ5 View 3D Structure Click here
A4ICW6 View 3D Structure Click here
A4IE43 View 3D Structure Click here
A4LBC2 View 3D Structure Click here
A8E7F0 View 3D Structure Click here
B0BN36 View 3D Structure Click here
B0G196 View 3D Structure Click here
B0S656 View 3D Structure Click here
B4F9T1 View 3D Structure Click here
B4FRT5 View 3D Structure Click here
B4FVH7 View 3D Structure Click here
B5DFE2 View 3D Structure Click here
B6TYP5 View 3D Structure Click here
B7ZVG0 View 3D Structure Click here
B7ZZW9 View 3D Structure Click here
B8JIA4 View 3D Structure Click here
B9FF78 View 3D Structure Click here
C0P715 View 3D Structure Click here
C7G064 View 3D Structure Click here
D3ZEB9 View 3D Structure Click here
D3ZI87 View 3D Structure Click here
D3ZIH5 View 3D Structure Click here
D3ZII8 View 3D Structure Click here
D3ZQA6 View 3D Structure Click here
D3ZSK5 View 3D Structure Click here
D4A2W7 View 3D Structure Click here
D4A3D2 View 3D Structure Click here
D4A7S1 View 3D Structure Click here
D4A9J4 View 3D Structure Click here
D4AA06 View 3D Structure Click here
D4ADE5 View 3D Structure Click here
D4AEC7 View 3D Structure Click here
E7EZZ6 View 3D Structure Click here
E7FFB7 View 3D Structure Click here
E9AGJ2 View 3D Structure Click here
E9AGY4 View 3D Structure Click here
E9AH76 View 3D Structure Click here
E9AH82 View 3D Structure Click here
E9PYH6 View 3D Structure Click here
E9Q3T6 View 3D Structure Click here
E9Q5F9 View 3D Structure Click here
E9QGQ0 View 3D Structure Click here
F1LWJ1 View 3D Structure Click here
F1LZH3 View 3D Structure Click here
F1Q9U2 View 3D Structure Click here
F1Q9U9 View 3D Structure Click here
F1QCY6 View 3D Structure Click here
F1QDG9 View 3D Structure Click here
F1QGQ8 View 3D Structure Click here
F1QJD2 View 3D Structure Click here
F1QJX1 View 3D Structure Click here
F1QKB1 View 3D Structure Click here
F1QUA6 View 3D Structure Click here
F1RET2 View 3D Structure Click here
F4HU79 View 3D Structure Click here
F4K1J4 View 3D Structure Click here
F6NN10 View 3D Structure Click here
G3V6S6 View 3D Structure Click here
G3V6U9 View 3D Structure Click here
G5EEU2 View 3D Structure Click here
G5EGI1 View 3D Structure Click here
I1J986 View 3D Structure Click here
I1JRR3 View 3D Structure Click here
I1JVX0 View 3D Structure Click here
I1JY36 View 3D Structure Click here
I1JYS9 View 3D Structure Click here
I1JZ98 View 3D Structure Click here
I1K5L1 View 3D Structure Click here
I1KAR4 View 3D Structure Click here
I1KBH7 View 3D Structure Click here
I1KHV6 View 3D Structure Click here
I1KKL7 View 3D Structure Click here
I1KMF9 View 3D Structure Click here
I1KQB1 View 3D Structure Click here
I1KWS1 View 3D Structure Click here
I1LDE3 View 3D Structure Click here
I1LHC7 View 3D Structure Click here
I1LRT6 View 3D Structure Click here
I1LU77 View 3D Structure Click here
I1LU88 View 3D Structure Click here
I1M0I3 View 3D Structure Click here
I1M406 View 3D Structure Click here
I1MBQ7 View 3D Structure Click here
I1MGT8 View 3D Structure Click here
I1MII9 View 3D Structure Click here
I1MQB2 View 3D Structure Click here
I1MSR3 View 3D Structure Click here
I1N3L2 View 3D Structure Click here
I1NDM7 View 3D Structure Click here
I1NGV6 View 3D Structure Click here
I1NIE2 View 3D Structure Click here
K7K280 View 3D Structure Click here
K7K3X0 View 3D Structure Click here
K7K4I0 View 3D Structure Click here
K7K4X0 View 3D Structure Click here
K7K5W6 View 3D Structure Click here
K7K6P9 View 3D Structure Click here
K7KEJ7 View 3D Structure Click here
K7KFI8 View 3D Structure Click here
K7KGC4 View 3D Structure Click here
K7KGG9 View 3D Structure Click here
K7KM54 View 3D Structure Click here
K7KUK4 View 3D Structure Click here
K7KUY6 View 3D Structure Click here
K7KWM0 View 3D Structure Click here
K7KY87 View 3D Structure Click here
K7KYG6 View 3D Structure Click here
K7L5P5 View 3D Structure Click here
K7LBW1 View 3D Structure Click here
K7LE53 View 3D Structure Click here
K7LG80 View 3D Structure Click here
K7LGU2 View 3D Structure Click here
K7LHC7 View 3D Structure Click here
K7LL17 View 3D Structure Click here
K7LMX3 View 3D Structure Click here
K7LNB1 View 3D Structure Click here
K7LZD4 View 3D Structure Click here
K7MBL3 View 3D Structure Click here
K7MEU6 View 3D Structure Click here
K7MHC3 View 3D Structure Click here
K7MHR5 View 3D Structure Click here
K7MN78 View 3D Structure Click here
K7MV89 View 3D Structure Click here
K7MWT7 View 3D Structure Click here
K7MYR2 View 3D Structure Click here
K7N0L2 View 3D Structure Click here
K7N1Z6 View 3D Structure Click here
K7N541 View 3D Structure Click here
M0R767 View 3D Structure Click here
M0RA29 View 3D Structure Click here
M9PGH7 View 3D Structure Click here
O14026 View 3D Structure Click here
O14135 View 3D Structure Click here
O15047 View 3D Structure Click here
O17186 View 3D Structure Click here
O17514 View 3D Structure Click here
O17679 View 3D Structure Click here
O22781 View 3D Structure Click here
O23372 View 3D Structure Click here
O42925 View 3D Structure Click here
O43463 View 3D Structure Click here
O44498 View 3D Structure Click here
O44757 View 3D Structure Click here
O46040 View 3D Structure Click here
O54864 View 3D Structure Click here
O60016 View 3D Structure Click here
O64827 View 3D Structure Click here
O65312 View 3D Structure Click here
O74405 View 3D Structure Click here
O74467 View 3D Structure Click here
O74738 View 3D Structure Click here
O75626 View 3D Structure Click here
O82175 View 3D Structure Click here
O88491 View 3D Structure Click here
O88974 View 3D Structure Click here
O94256 View 3D Structure Click here
O96028 View 3D Structure Click here
P0C2N5 View 3D Structure Click here
P0C2N6 View 3D Structure Click here
P0C6Y7 View 3D Structure Click here
P0CB22 View 3D Structure Click here
P34318 View 3D Structure Click here
P34544 View 3D Structure Click here
P36124 View 3D Structure Click here
P38222 View 3D Structure Click here
P38827 View 3D Structure Click here
P38890 View 3D Structure Click here
P42124 View 3D Structure Click here
P42948 View 3D Structure Click here
P45975 View 3D Structure Click here
P46995 View 3D Structure Click here
P58467 View 3D Structure Click here
P70351 View 3D Structure Click here
P93831 View 3D Structure Click here
P97443 View 3D Structure Click here
Q06ZW3 View 3D Structure Click here
Q071E0 View 3D Structure Click here
Q08BR4 View 3D Structure Click here
Q08BS4 View 3D Structure Click here
Q08C84 View 3D Structure Click here
Q09265 View 3D Structure Click here
Q0DY89 View 3D Structure Click here
Q0JD76 View 3D Structure Click here
Q10MI4 View 3D Structure Click here
Q12504 View 3D Structure Click here
Q12529 View 3D Structure Click here
Q13029 View 3D Structure Click here
Q15047 View 3D Structure Click here
Q15910 View 3D Structure Click here
Q18221 View 3D Structure Click here
Q19117 View 3D Structure Click here
Q1L8U8 View 3D Structure Click here
Q1LY77 View 3D Structure Click here
Q21404 View 3D Structure Click here
Q22795 View 3D Structure Click here
Q2LAE1 View 3D Structure Click here
Q2MJQ9 View 3D Structure Click here
Q2QM91 View 3D Structure Click here
Q2R1K5 View 3D Structure Click here
Q2YDW7 View 3D Structure Click here
Q32KD2 View 3D Structure Click here
Q337E1 View 3D Structure Click here
Q338E2 View 3D Structure Click here
Q3EC60 View 3D Structure Click here
Q3ECY6 View 3D Structure Click here
Q3TYX3 View 3D Structure Click here
Q3U8K7 View 3D Structure Click here
Q3UG20 View 3D Structure Click here
Q3UZD5 View 3D Structure Click here
Q4CKT3 View 3D Structure Click here
Q4CNS5 View 3D Structure Click here
Q4CNX1 View 3D Structure Click here
Q4CSI7 View 3D Structure Click here
Q4CTU9 View 3D Structure Click here
Q4CU83 View 3D Structure Click here
Q4CUB0 View 3D Structure Click here
Q4CUZ7 View 3D Structure Click here
Q4CYF2 View 3D Structure Click here
Q4CYF5 View 3D Structure Click here
Q4CZ86 View 3D Structure Click here
Q4D060 View 3D Structure Click here
Q4D1Q7 View 3D Structure Click here
Q4D225 View 3D Structure Click here
Q4D2N2 View 3D Structure Click here
Q4D5M3 View 3D Structure Click here
Q4D5W7 View 3D Structure Click here
Q4D7T3 View 3D Structure Click here
Q4D926 View 3D Structure Click here
Q4D984 View 3D Structure Click here
Q4D9B3 View 3D Structure Click here
Q4D9E8 View 3D Structure Click here
Q4DAH1 View 3D Structure Click here
Q4DAV0 View 3D Structure Click here
Q4DBM3 View 3D Structure Click here
Q4DBV5 View 3D Structure Click here
Q4DH30 View 3D Structure Click here
Q4DH93 View 3D Structure Click here
Q4DJI6 View 3D Structure Click here
Q4DJI6 View 3D Structure Click here
Q4DJI6 View 3D Structure Click here
Q4DKR4 View 3D Structure Click here
Q4DL12 View 3D Structure Click here
Q4DLK7 View 3D Structure Click here
Q4DLX1 View 3D Structure Click here
Q4DMW0 View 3D Structure Click here
Q4DQY4 View 3D Structure Click here
Q4DT70 View 3D Structure Click here
Q4DTV4 View 3D Structure Click here
Q4DUN3 View 3D Structure Click here
Q4DXI3 View 3D Structure Click here
Q4DY62 View 3D Structure Click here
Q4DY69 View 3D Structure Click here
Q4DYN5 View 3D Structure Click here
Q4DZ08 View 3D Structure Click here
Q4DZ21 View 3D Structure Click here
Q4DZM0 View 3D Structure Click here
Q4DZQ7 View 3D Structure Click here
Q4DZZ2 View 3D Structure Click here
Q4E025 View 3D Structure Click here
Q4E137 View 3D Structure Click here
Q4E141 View 3D Structure Click here
Q4E1E1 View 3D Structure Click here
Q4E302 View 3D Structure Click here
Q4E5A9 View 3D Structure Click here
Q4E5S8 View 3D Structure Click here
Q4E668 View 3D Structure Click here
Q4FZB7 View 3D Structure Click here
Q53H47 View 3D Structure Click here
Q54C43 View 3D Structure Click here
Q54C79 View 3D Structure Click here
Q54D67 View 3D Structure Click here
Q54DL6 View 3D Structure Click here
Q54GG3 View 3D Structure Click here
Q54HS3 View 3D Structure Click here
Q54IV4 View 3D Structure Click here
Q54J70 View 3D Structure Click here
Q54JW6 View 3D Structure Click here
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