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137  structures 3530  species 0  interactions 9834  sequences 241  architectures

Family: Gal_mutarotas_2 (PF13802)

Summary: Galactose mutarotase-like

Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.

The Pfam group coordinates the annotation of Pfam families in Wikipedia, but we have not yet assigned a Wikipedia article to this family. If you think that a particular Wikipedia article provides good annotation, please let us know.

This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.

Galactose mutarotase-like Provide feedback

This family is found N-terminal to glycosyl-hydrolase domains, and appears to be similar to the galactose mutarotase superfamily.

This tab holds annotation information from the InterPro database.

InterPro entry IPR025887

This domain is found in proteins that belong to the glycoside hydrolase family 31. The domain appears to be similar to the galactose mutarotase superfamily.

Domain organisation

Below is a listing of the unique domain organisations or architectures in which this domain is found. More...

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Pfam Clan

This family is a member of clan Gal_mutarotase (CL0103), which has the following description:

This clan is composed of a beta-sandwich that was first observed in domain 5 of beta-galactosidase, then as the central domain of copper amine oxidase, the C-terminal domain of chondroitinase, the C-terminal domain of hyaluronate lyase, the N-terminal domain of maltose phosphorylase and in Galactose Mutarotase [1]. All these enzymes act on a sugar substrate.

The clan contains the following 32 members:

Aldose_epim Bgal_small_N Cu_amine_oxid DUF1926 DUF4432 DUF4450 DUF4968 DUF5054 DUF5107 DUF5127 DUF5703_N Gal_mutarotas_2 Gal_mutarotas_3 GH97_N Glucodextran_N Glyco_hyd_65N_2 Glyco_hydr_116N Glyco_hydro_36N Glyco_hydro_38 Glyco_hydro_38C Glyco_hydro_52 Glyco_hydro_65N Glyco_hydro_81 Glyco_hydro_92N Glyco_transf_36 Hepar_II_III Lyase_8 MdoG NtCtMGAM_N Rhamnogal_lyase RhgB_N YidC_periplas

Alignments

We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets and the UniProtKB sequence database. More...

View options

We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(315)
Full
(9834)
Representative proteomes UniProt
(26514)
RP15
(1337)
RP35
(4294)
RP55
(8558)
RP75
(12936)
Jalview View  View  View  View  View  View  View 
HTML View             
PP/heatmap 1            

1Cannot generate PP/Heatmap alignments for seeds; no PP data available

Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(315)
Full
(9834)
Representative proteomes UniProt
(26514)
RP15
(1337)
RP35
(4294)
RP55
(8558)
RP75
(12936)
Alignment:
Format:
Order:
Sequence:
Gaps:
Download/view:

Download options

We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(315)
Full
(9834)
Representative proteomes UniProt
(26514)
RP15
(1337)
RP35
(4294)
RP55
(8558)
RP75
(12936)
Raw Stockholm Download   Download   Download   Download   Download   Download   Download  
Gzipped Download   Download   Download   Download   Download   Download   Download  

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

HMM logo

HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...

Trees

This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.

Note: You can also download the data file for the tree.

Curation and family details

This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.

Curation View help on the curation process

Seed source: Jackhmmer:Q8FC64
Previous IDs: none
Type: Domain
Sequence Ontology: SO:0000417
Author: Coggill P
Number in seed: 315
Number in full: 9834
Average length of the domain: 68.10 aa
Average identity of full alignment: 28 %
Average coverage of the sequence by the domain: 7.80 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 27.0 27.0
Trusted cut-off 27.0 27.0
Noise cut-off 26.9 26.9
Model length: 68
Family (HMM) version: 8
Download: download the raw HMM for this family

Species distribution

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Archea Archea Eukaryota Eukaryota
Bacteria Bacteria Other sequences Other sequences
Viruses Viruses Unclassified Unclassified
Viroids Viroids Unclassified sequence Unclassified sequence

Selections

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This visualisation provides a simple graphical representation of the distribution of this family across species. You can find the original interactive tree in the adjacent tab. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Gal_mutarotas_2 domain has been found. There are 137 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.

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AlphaFold Structure Predictions

The list of proteins below match this family and have AlphaFold predicted structures. Click on the protein accession to view the predicted structure.

Protein Predicted structure External Information
A0A0G2L1N0 View 3D Structure Click here
A0A0P0X5N3 View 3D Structure Click here
A0A0R0I6Y6 View 3D Structure Click here
A0A0R0JT00 View 3D Structure Click here
A0A1D6EMY1 View 3D Structure Click here
A0A1D6HXT2 View 3D Structure Click here
A0A1D6LPQ2 View 3D Structure Click here
A0A1D6MM31 View 3D Structure Click here
A0A1I9LTS6 View 3D Structure Click here
A0A2R8QK09 View 3D Structure Click here
A0A571BDS5 View 3D Structure Click here
A4HXN5 View 3D Structure Click here
B3DIZ3 View 3D Structure Click here
B9F676 View 3D Structure Click here
C0PHF3 View 3D Structure Click here
D3ZAN3 View 3D Structure Click here
D3ZTX4 View 3D Structure Click here
D4A7G5 View 3D Structure Click here
E7F6D4 View 3D Structure Click here
E7FCP7 View 3D Structure Click here
F1Q6Z9 View 3D Structure Click here
F4J6T7 View 3D Structure Click here
F8VQM5 View 3D Structure Click here
I1J6K4 View 3D Structure Click here
I1JVV8 View 3D Structure Click here
I1JXY2 View 3D Structure Click here
I1KWV4 View 3D Structure Click here
I1LEX2 View 3D Structure Click here
I1MG74 View 3D Structure Click here
K7VP34 View 3D Structure Click here
O17352 View 3D Structure Click here
P10253 View 3D Structure Click here
P31434 View 3D Structure Click here
P38138 View 3D Structure Click here
P70699 View 3D Structure Click here
Q0D6X6 View 3D Structure Click here
Q0JQZ2 View 3D Structure Click here
Q14697 View 3D Structure Click here
Q19004 View 3D Structure Click here
Q20239 View 3D Structure Click here
Q2M2H8 View 3D Structure Click here
Q2M2H8 View 3D Structure Click here
Q4CZY1 View 3D Structure Click here
Q4E1V5 View 3D Structure Click here
Q55D50 View 3D Structure Click here
Q5A4X3 View 3D Structure Click here
Q653V4 View 3D Structure Click here
Q653V7 View 3D Structure Click here
Q6P7A9 View 3D Structure Click here
Q7KMM4 View 3D Structure Click here
Q8BHN3 View 3D Structure Click here
Q8BVW0 View 3D Structure Click here
Q8TET4 View 3D Structure Click here
Q94502 View 3D Structure Click here
Q9FN05 View 3D Structure Click here
Q9LYF8 View 3D Structure Click here
Q9S7Y7 View 3D Structure Click here
Q9US55 View 3D Structure Click here