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52  structures 1692  species 0  interactions 19031  sequences 281  architectures

Family: Myb_DNA-bind_6 (PF13921)

Summary: Myb-like DNA-binding domain

Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.

The Pfam group coordinates the annotation of Pfam families in Wikipedia, but we have not yet assigned a Wikipedia article to this family. If you think that a particular Wikipedia article provides good annotation, please let us know.

This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.

Myb-like DNA-binding domain Provide feedback

This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family [1].

Literature references

  1. Aasland R, Stewart AF, Gibson T; , Trends Biochem Sci 1996;21:87-88.: The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB. PUBMED:8882580 EPMC:8882580


Internal database links

This tab holds annotation information from the InterPro database.

No InterPro data for this Pfam family.

Domain organisation

Below is a listing of the unique domain organisations or architectures in which this domain is found. More...

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Pfam Clan

This family is a member of clan HTH (CL0123), which has the following description:

This family contains a diverse range of mostly DNA-binding domains that contain a helix-turn-helix motif.

The clan contains the following 353 members:

AbiEi_3_N AbiEi_4 ANAPC2 AphA_like AraR_C Arg_repressor ARID ArsR B-block_TFIIIC B5 Bac_DnaA_C Baculo_PEP_N BetR BHD_3 BLACT_WH Bot1p BrkDBD BsuBI_PstI_RE_N C_LFY_FLO CaiF_GrlA CarD_CdnL_TRCF CDC27 Cdc6_C Cdh1_DBD_1 CDT1 CDT1_C CENP-B_N Costars CPSase_L_D3 Cro Crp CSN4_RPN5_eIF3a CSN8_PSD8_EIF3K CtsR Cullin_Nedd8 CUT CUTL CvfB_WH DBD_HTH DDRGK DEP Dimerisation Dimerisation2 DNA_meth_N DpnI_C DprA_WH DsrC DsrD DUF1016_N DUF1133 DUF1153 DUF1323 DUF134 DUF1441 DUF1492 DUF1495 DUF1670 DUF1804 DUF1819 DUF1836 DUF1870 DUF2089 DUF2250 DUF2316 DUF2513 DUF2582 DUF3116 DUF3253 DUF3853 DUF3860 DUF3908 DUF433 DUF4364 DUF4423 DUF4447 DUF480 DUF4817 DUF5635 DUF573 DUF6088 DUF6262 DUF6362 DUF6432 DUF6462 DUF6471 DUF722 DUF739 DUF742 DUF977 E2F_TDP EAP30 eIF-5_eIF-2B ELL ESCRT-II Ets EutK_C Exc F-112 FaeA Fe_dep_repr_C Fe_dep_repress FeoC FokI_C FokI_N Forkhead FtsK_gamma FUR GcrA GerE GntR GP3_package HARE-HTH HemN_C HNF-1_N Homeobox_KN Homeodomain Homez HPD HrcA_DNA-bdg HSF_DNA-bind HTH_1 HTH_10 HTH_11 HTH_12 HTH_13 HTH_15 HTH_16 HTH_17 HTH_18 HTH_19 HTH_20 HTH_21 HTH_22 HTH_23 HTH_24 HTH_25 HTH_26 HTH_27 HTH_28 HTH_29 HTH_3 HTH_30 HTH_31 HTH_32 HTH_33 HTH_34 HTH_35 HTH_36 HTH_37 HTH_38 HTH_39 HTH_40 HTH_41 HTH_42 HTH_43 HTH_45 HTH_46 HTH_47 HTH_48 HTH_49 HTH_5 HTH_50 HTH_51 HTH_52 HTH_53 HTH_54 HTH_55 HTH_56 HTH_57 HTH_58 HTH_59 HTH_6 HTH_7 HTH_8 HTH_9 HTH_ABP1_N HTH_AraC HTH_AsnC-type HTH_CodY HTH_Crp_2 HTH_DeoR HTH_IclR HTH_Mga HTH_micro HTH_OrfB_IS605 HTH_PafC HTH_ParB HTH_psq HTH_SUN2 HTH_Tnp_1 HTH_Tnp_1_2 HTH_Tnp_4 HTH_Tnp_IS1 HTH_Tnp_IS630 HTH_Tnp_ISL3 HTH_Tnp_Mu_1 HTH_Tnp_Mu_2 HTH_Tnp_Tc3_1 HTH_Tnp_Tc3_2 HTH_Tnp_Tc5 HTH_WhiA HxlR IBD IF2_N IRF KicB KilA-N Kin17_mid KORA KorB La LacI LexA_DNA_bind Linker_histone LZ_Tnp_IS481 MADF_DNA_bdg MAGE MARF1_LOTUS MarR MarR_2 MerR MerR-DNA-bind MerR_1 MerR_2 Mga Mnd1 MogR_DNAbind Mor MotA_activ MqsA_antitoxin MRP-L20 MukE Myb_DNA-bind_2 Myb_DNA-bind_3 Myb_DNA-bind_4 Myb_DNA-bind_5 Myb_DNA-bind_6 Myb_DNA-bind_7 Myb_DNA-binding Neugrin NFRKB_winged NOD2_WH NUMOD1 ORC_WH_C OST-HTH P22_Cro PaaX PadR PapB PAX PCI Penicillinase_R Phage_AlpA Phage_antitermQ Phage_CI_repr Phage_CII Phage_NinH Phage_Nu1 Phage_rep_O Phage_rep_org_N Phage_terminase PheRS_DBD1 PheRS_DBD2 PheRS_DBD3 Pou Pox_D5 PqqD PRC2_HTH_1 PUFD PuR_N Put_DNA-bind_N pXO2-72 Raf1_HTH Rap1-DNA-bind Rep_3 RepA_C RepA_N RepC RepL Replic_Relax RFX_DNA_binding Ribosomal_S18 Ribosomal_S19e Ribosomal_S25 Rio2_N RNA_pol_Rpc34 RNA_pol_Rpc82 RNase_H2-Ydr279 ROQ_II RP-C RPA RPA_C RQC Rrf2 RTP RuvB_C S10_plectin SAC3_GANP SANT_DAMP1_like SatD SelB-wing_1 SelB-wing_2 SelB-wing_3 SgrR_N Sigma54_CBD Sigma54_DBD Sigma70_ECF Sigma70_ner Sigma70_r2 Sigma70_r3 Sigma70_r4 Sigma70_r4_2 SinI Ski_Sno SLIDE Slx4 SMC_Nse1 SMC_ScpB SoPB_HTH SpoIIID SRP19 SRP_SPB STN1_2 Sulfolobus_pRN Suv3_N Swi6_N SWIRM Tau95 TBPIP TEA Terminase_5 TetR_N TFA2_Winged_2 TFIIE_alpha TFIIE_beta TFIIF_alpha TFIIF_beta Tn7_Tnp_TnsA_C Tn916-Xis TraI_2_C Trans_reg_C TrfA TrmB tRNA_bind_2 tRNA_bind_3 Trp_repressor UPF0122 UPF0175 Vir_act_alpha_C YdaS_antitoxin YjcQ YokU z-alpha

Alignments

We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets and the UniProtKB sequence database. More...

View options

We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(29)
Full
(19031)
Representative proteomes UniProt
(33816)
RP15
(4309)
RP35
(10020)
RP55
(15518)
RP75
(20535)
Jalview View  View  View  View  View  View  View 
HTML View             
PP/heatmap 1            

1Cannot generate PP/Heatmap alignments for seeds; no PP data available

Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(29)
Full
(19031)
Representative proteomes UniProt
(33816)
RP15
(4309)
RP35
(10020)
RP55
(15518)
RP75
(20535)
Alignment:
Format:
Order:
Sequence:
Gaps:
Download/view:

Download options

We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(29)
Full
(19031)
Representative proteomes UniProt
(33816)
RP15
(4309)
RP35
(10020)
RP55
(15518)
RP75
(20535)
Raw Stockholm Download   Download   Download   Download   Download   Download   Download  
Gzipped Download   Download   Download   Download   Download   Download   Download  

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

HMM logo

HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...

Trees

This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.

Note: You can also download the data file for the tree.

Curation and family details

This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.

Curation View help on the curation process

Seed source: Jackhmmer:Q15361
Previous IDs: none
Type: Domain
Sequence Ontology: SO:0000417
Author: Coggill P
Number in seed: 29
Number in full: 19031
Average length of the domain: 60.30 aa
Average identity of full alignment: 27 %
Average coverage of the sequence by the domain: 15.13 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 22.9 22.9
Trusted cut-off 22.9 22.9
Noise cut-off 22.8 22.8
Model length: 60
Family (HMM) version: 8
Download: download the raw HMM for this family

Species distribution

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Colour assignments

Archea Archea Eukaryota Eukaryota
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Viruses Viruses Unclassified Unclassified
Viroids Viroids Unclassified sequence Unclassified sequence

Selections

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This visualisation provides a simple graphical representation of the distribution of this family across species. You can find the original interactive tree in the adjacent tab. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Myb_DNA-bind_6 domain has been found. There are 52 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.

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AlphaFold Structure Predictions

The list of proteins below match this family and have AlphaFold predicted structures. Click on the protein accession to view the predicted structure.

Protein Predicted structure External Information
A0A0K2CTB2 View 3D Structure Click here
A0A0K2CTB2 View 3D Structure Click here
A0A0P0VZL7 View 3D Structure Click here
A0A0P0W9C3 View 3D Structure Click here
A0A0P0W9C3 View 3D Structure Click here
A0A0P0WSX1 View 3D Structure Click here
A0A0P0WSX1 View 3D Structure Click here
A0A0P0WVK7 View 3D Structure Click here
A0A0P0XGE9 View 3D Structure Click here
A0A0P0XGE9 View 3D Structure Click here
A0A0P0Y7N5 View 3D Structure Click here
A0A0P0Y7N5 View 3D Structure Click here
A0A0P0Y8F4 View 3D Structure Click here
A0A0P0Y8F4 View 3D Structure Click here
A0A0R0ESD1 View 3D Structure Click here
A0A0R0ESD1 View 3D Structure Click here
A0A0R0FNI5 View 3D Structure Click here
A0A0R0GJT2 View 3D Structure Click here
A0A0R0GJT2 View 3D Structure Click here
A0A0R0IFW0 View 3D Structure Click here
A0A0R0J4B4 View 3D Structure Click here
A0A0R0J8B9 View 3D Structure Click here
A0A0R0K3K9 View 3D Structure Click here
A0A0R0K3K9 View 3D Structure Click here
A0A0R0K6Z5 View 3D Structure Click here
A0A0R0K6Z5 View 3D Structure Click here
A0A0R0KFP6 View 3D Structure Click here
A0A0R0KHA6 View 3D Structure Click here
A0A0R0KHA6 View 3D Structure Click here
A0A178VEK7 View 3D Structure Click here
A0A1D6E421 View 3D Structure Click here
A0A1D6F243 View 3D Structure Click here
A0A1D6F243 View 3D Structure Click here
A0A1D6FLM0 View 3D Structure Click here
A0A1D6G2X0 View 3D Structure Click here
A0A1D6G8L0 View 3D Structure Click here
A0A1D6G8L0 View 3D Structure Click here
A0A1D6GSP4 View 3D Structure Click here
A0A1D6GSP4 View 3D Structure Click here
A0A1D6H4Z3 View 3D Structure Click here
A0A1D6H4Z3 View 3D Structure Click here
A0A1D6H4Z3 View 3D Structure Click here
A0A1D6IWW0 View 3D Structure Click here
A0A1D6JD85 View 3D Structure Click here
A0A1D6KE42 View 3D Structure Click here
A0A1D6KJA2 View 3D Structure Click here
A0A1D6KP30 View 3D Structure Click here
A0A1D6KP30 View 3D Structure Click here
A0A1D6L7W7 View 3D Structure Click here
A0A1D6L7W7 View 3D Structure Click here
A0A1D6LPK8 View 3D Structure Click here
A0A1D6MF55 View 3D Structure Click here
A0A1D6MF55 View 3D Structure Click here
A0A1D6MQP3 View 3D Structure Click here
A0A1D6MQP3 View 3D Structure Click here
A0A1D6N2M1 View 3D Structure Click here
A0A1D6N2M1 View 3D Structure Click here
A0A1D6N9Q5 View 3D Structure Click here
A0A1D6NK70 View 3D Structure Click here
A0A1D6PVQ9 View 3D Structure Click here
A0A1D8PQ76 View 3D Structure Click here
A0A1D8PQ76 View 3D Structure Click here
A0A1D8PS02 View 3D Structure Click here
A0A1W2P6Q8 View 3D Structure Click here
A0A1W2P6Q8 View 3D Structure Click here
A0A1W2P7H4 View 3D Structure Click here
A0A1W2P7H4 View 3D Structure Click here
A0A1W2P7S8 View 3D Structure Click here
A0A1W2P7S8 View 3D Structure Click here
A0A1W2P7Z8 View 3D Structure Click here
A0A1W2P7Z8 View 3D Structure Click here
A0A1W2P855 View 3D Structure Click here
A0A1W2P855 View 3D Structure Click here
A0A2R8QH49 View 3D Structure Click here
A0A2R8QH49 View 3D Structure Click here
A0A368UGR2 View 3D Structure Click here
A0A368UGR2 View 3D Structure Click here
B0G0Y5 View 3D Structure Click here
B0G0Y5 View 3D Structure Click here
B4FX89 View 3D Structure Click here
B4FX89 View 3D Structure Click here
B6TWV8 View 3D Structure Click here
B6TWV8 View 3D Structure Click here
D3ZF01 View 3D Structure Click here
D3ZF01 View 3D Structure Click here
D3ZF01 View 3D Structure Click here
D3ZLC6 View 3D Structure Click here
D4A1Z7 View 3D Structure Click here
D4A3C9 View 3D Structure Click here
D4A3C9 View 3D Structure Click here
D4A3C9 View 3D Structure Click here
D4A3C9 View 3D Structure Click here
E9QDD4 View 3D Structure Click here
E9QDM8 View 3D Structure Click here
E9QIC1 View 3D Structure Click here
E9QIC1 View 3D Structure Click here
F1Q786 View 3D Structure Click here
F1QGY5 View 3D Structure Click here
F1QGY5 View 3D Structure Click here
F1QGY5 View 3D Structure Click here
F1R591 View 3D Structure Click here
F4IB54 View 3D Structure Click here
F4J7T2 View 3D Structure Click here
F4J7T3 View 3D Structure Click here
G5EFC4 View 3D Structure Click here
G5EFC4 View 3D Structure Click here
I1J738 View 3D Structure Click here
I1J738 View 3D Structure Click here
I1JBN1 View 3D Structure Click here
I1JBN1 View 3D Structure Click here
I1JHB9 View 3D Structure Click here
I1JHB9 View 3D Structure Click here
I1JK61 View 3D Structure Click here
I1JK61 View 3D Structure Click here
I1JLW1 View 3D Structure Click here
I1JLW1 View 3D Structure Click here
I1JRS3 View 3D Structure Click here
I1JRS3 View 3D Structure Click here
I1JTH1 View 3D Structure Click here
I1JTH1 View 3D Structure Click here
I1KXR7 View 3D Structure Click here
I1KXR7 View 3D Structure Click here
I1L3Z6 View 3D Structure Click here
I1L3Z6 View 3D Structure Click here
I1LBQ2 View 3D Structure Click here
I1LBQ2 View 3D Structure Click here
I1LYQ8 View 3D Structure Click here
I1M102 View 3D Structure Click here
I1M8R4 View 3D Structure Click here
I1M8R4 View 3D Structure Click here
I1MQM9 View 3D Structure Click here
I1MQM9 View 3D Structure Click here
I1N1S3 View 3D Structure Click here
I1N1S3 View 3D Structure Click here
I1NCD2 View 3D Structure Click here
I1NCD2 View 3D Structure Click here
I1NIN5 View 3D Structure Click here
I1NIN5 View 3D Structure Click here
K7K1S1 View 3D Structure Click here
K7K1S1 View 3D Structure Click here
K7KDQ7 View 3D Structure Click here
K7KDR9 View 3D Structure Click here
K7KDR9 View 3D Structure Click here
K7KEG5 View 3D Structure Click here
K7KMR3 View 3D Structure Click here
K7KMR3 View 3D Structure Click here
K7KNL9 View 3D Structure Click here
K7KNL9 View 3D Structure Click here
K7KUM6 View 3D Structure Click here
K7KUM6 View 3D Structure Click here
K7KVS4 View 3D Structure Click here
K7KVS4 View 3D Structure Click here
K7L0S7 View 3D Structure Click here
K7L1G6 View 3D Structure Click here
K7L1G6 View 3D Structure Click here
K7LA48 View 3D Structure Click here
K7LA48 View 3D Structure Click here
K7LB18 View 3D Structure Click here
K7LCR2 View 3D Structure Click here
K7LCR2 View 3D Structure Click here
K7M767 View 3D Structure Click here
K7M767 View 3D Structure Click here
K7M809 View 3D Structure Click here
K7M809 View 3D Structure Click here
K7MAR8 View 3D Structure Click here
K7MFP5 View 3D Structure Click here
K7MFP5 View 3D Structure Click here
K7ML94 View 3D Structure Click here
K7MNR7 View 3D Structure Click here
K7MNR7 View 3D Structure Click here
K7MQB8 View 3D Structure Click here
K7MQB8 View 3D Structure Click here
K7MRL3 View 3D Structure Click here
K7MRL3 View 3D Structure Click here
K7MSU2 View 3D Structure Click here
K7MT37 View 3D Structure Click here
K7MT37 View 3D Structure Click here
K7N1M5 View 3D Structure Click here
O08837 View 3D Structure Click here
O08837 View 3D Structure Click here
O59773 View 3D Structure Click here
O80931 View 3D Structure Click here
O80931 View 3D Structure Click here
P10243 View 3D Structure Click here
P10243 View 3D Structure Click here
P10243 View 3D Structure Click here
P10244 View 3D Structure Click here
P21538 View 3D Structure Click here
P48972 View 3D Structure Click here
P51960 View 3D Structure Click here
P51960 View 3D Structure Click here
P51960 View 3D Structure Click here
P91868 View 3D Structure Click here
P92948 View 3D Structure Click here
P92948 View 3D Structure Click here
Q06337 View 3D Structure Click here
Q0J3I9 View 3D Structure Click here
Q0J3I9 View 3D Structure Click here
Q0JB89 View 3D Structure Click here
Q0PJI9 View 3D Structure Click here
Q0PJI9 View 3D Structure Click here
Q0PJL2 View 3D Structure Click here
Q0PJL2 View 3D Structure Click here
Q15361 View 3D Structure Click here
Q1PDP9 View 3D Structure Click here
Q1PDP9 View 3D Structure Click here
Q4DFE9 View 3D Structure Click here
Q4E1M0 View 3D Structure Click here
Q4VPE5 View 3D Structure Click here
Q4VPE5 View 3D Structure Click here
Q54CT1 View 3D Structure Click here
Q54CT1 View 3D Structure Click here
Q54HP1 View 3D Structure Click here
Q54HP1 View 3D Structure Click here
Q54NA6 View 3D Structure Click here
Q54WZ0 View 3D Structure Click here
Q54WZ0 View 3D Structure Click here
Q55GK3 View 3D Structure Click here
Q55GK3 View 3D Structure Click here
Q5A119 View 3D Structure Click here
Q5A683 View 3D Structure Click here
Q5A683 View 3D Structure Click here
Q5SXM2 View 3D Structure Click here
Q653P2 View 3D Structure Click here
Q655P0 View 3D Structure Click here
Q655P0 View 3D Structure Click here
Q67WF6 View 3D Structure Click here
Q67WF6 View 3D Structure Click here
Q6A068 View 3D Structure Click here
Q6A068 View 3D Structure Click here
Q6ESU2 View 3D Structure Click here
Q6R0C4 View 3D Structure Click here
Q6R0C4 View 3D Structure Click here
Q6Z5L1 View 3D Structure Click here
Q6Z5L1 View 3D Structure Click here
Q6ZBS5 View 3D Structure Click here
Q7KQL1 View 3D Structure Click here
Q7KQL1 View 3D Structure Click here
Q7KSD8 View 3D Structure Click here
Q84PV0 View 3D Structure Click here
Q8BP86 View 3D Structure Click here
Q8BP86 View 3D Structure Click here
Q8BP86 View 3D Structure Click here
Q8BP86 View 3D Structure Click here
Q8H1P9 View 3D Structure Click here
Q8H1P9 View 3D Structure Click here
Q8IEF6 View 3D Structure Click here
Q8LI26 View 3D Structure Click here
Q8LI26 View 3D Structure Click here
Q8W1W6 View 3D Structure Click here
Q8W1W6 View 3D Structure Click here
Q94FL6 View 3D Structure Click here
Q94FL6 View 3D Structure Click here
Q94FL9 View 3D Structure Click here
Q94IB1 View 3D Structure Click here
Q94IB1 View 3D Structure Click here
Q99459 View 3D Structure Click here
Q99459 View 3D Structure Click here
Q9FIM4 View 3D Structure Click here
Q9FIM4 View 3D Structure Click here
Q9FLM7 View 3D Structure Click here
Q9FY60 View 3D Structure Click here
Q9FY60 View 3D Structure Click here
Q9LVW4 View 3D Structure Click here
Q9LVW4 View 3D Structure Click here
Q9S7B2 View 3D Structure Click here
Q9S7B2 View 3D Structure Click here
Q9S7L2 View 3D Structure Click here
Q9S7L2 View 3D Structure Click here
Q9SM27 View 3D Structure Click here
Q9SM27 View 3D Structure Click here
Q9SPH0 View 3D Structure Click here
Q9SPH0 View 3D Structure Click here
Q9SPN3 View 3D Structure Click here
Q9SPN3 View 3D Structure Click here
Q9SPN3 View 3D Structure Click here
Q9SZC2 View 3D Structure Click here
Q9SZC2 View 3D Structure Click here
Q9VHX0 View 3D Structure Click here
Q9VWL4 View 3D Structure Click here
Q9W0R0 View 3D Structure Click here
Q9W0R0 View 3D Structure Click here