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419  structures 2730  species 0  interactions 10403  sequences 177  architectures

Family: Prot_ATP_ID_OB (PF16450)

Summary: Proteasomal ATPase OB C-terminal domain

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Proteasomal ATPase OB C-terminal domain Provide feedback

This is the interdomain (ID) or oligonucleotide binding (OB) domain of proteasomal ATPase [1-2]

Literature references

  1. Wang T, Li H, Lin G, Tang C, Li D, Nathan C, Darwin KH, Li H;, Structure. 2009;17:1377-1385.: Structural insights on the Mycobacterium tuberculosis proteasomal ATPase Mpa. PUBMED:19836337 EPMC:19836337

  2. Wang T, Darwin KH, Li H;, Nat Struct Mol Biol. 2010;17:1352-1357.: Binding-induced folding of prokaryotic ubiquitin-like protein on the Mycobacterium proteasomal ATPase targets substrates for degradation. PUBMED:20953180 EPMC:20953180


Internal database links

This tab holds annotation information from the InterPro database.

InterPro entry IPR032501

This is the interdomain (ID) or oligonucleotide binding (OB) domain of proteasomal ATPase [ PUBMED:19836337 , PUBMED:20953180 ].

Domain organisation

Below is a listing of the unique domain organisations or architectures in which this domain is found. More...

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Alignments

We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets and the UniProtKB sequence database. More...

View options

We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(89)
Full
(10403)
Representative proteomes UniProt
(21146)
RP15
(1921)
RP35
(4842)
RP55
(8505)
RP75
(11919)
Jalview View  View  View  View  View  View  View 
HTML View             
PP/heatmap 1            

1Cannot generate PP/Heatmap alignments for seeds; no PP data available

Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(89)
Full
(10403)
Representative proteomes UniProt
(21146)
RP15
(1921)
RP35
(4842)
RP55
(8505)
RP75
(11919)
Alignment:
Format:
Order:
Sequence:
Gaps:
Download/view:

Download options

We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(89)
Full
(10403)
Representative proteomes UniProt
(21146)
RP15
(1921)
RP35
(4842)
RP55
(8505)
RP75
(11919)
Raw Stockholm Download   Download   Download   Download   Download   Download   Download  
Gzipped Download   Download   Download   Download   Download   Download   Download  

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

HMM logo

HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...

Trees

This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.

Note: You can also download the data file for the tree.

Curation and family details

This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.

Curation View help on the curation process

Seed source: PDB:3fp9
Previous IDs: none
Type: Domain
Sequence Ontology: SO:0000417
Author: Eberhardt R , Bateman A
Number in seed: 89
Number in full: 10403
Average length of the domain: 59.90 aa
Average identity of full alignment: 33 %
Average coverage of the sequence by the domain: 13.52 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 21.4 21.4
Trusted cut-off 21.4 21.4
Noise cut-off 21.3 21.3
Model length: 56
Family (HMM) version: 7
Download: download the raw HMM for this family

Species distribution

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Archea Archea Eukaryota Eukaryota
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Viroids Viroids Unclassified sequence Unclassified sequence

Selections

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This visualisation provides a simple graphical representation of the distribution of this family across species. You can find the original interactive tree in the adjacent tab. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Prot_ATP_ID_OB domain has been found. There are 419 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.

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AlphaFold Structure Predictions

The list of proteins below match this family and have AlphaFold predicted structures. Click on the protein accession to view the predicted structure.

Protein Predicted structure External Information
A0A0R0ERR0 View 3D Structure Click here
A0A0R0ES83 View 3D Structure Click here
A0A0R0EW30 View 3D Structure Click here
A0A0R0EXW6 View 3D Structure Click here
A0A0R0GHN2 View 3D Structure Click here
A0A0R0KRE0 View 3D Structure Click here
A0A0R4IFE2 View 3D Structure Click here
A0A0R4ILA8 View 3D Structure Click here
A0A0R4J302 View 3D Structure Click here
A0A0R4J305 View 3D Structure Click here
A0A0R4J3Y6 View 3D Structure Click here
A0A0R4J439 View 3D Structure Click here
A0A0R4J4L8 View 3D Structure Click here
A0A0R4J4W3 View 3D Structure Click here
A0A1D6F4V7 View 3D Structure Click here
A0A1D6H4H6 View 3D Structure Click here
A0A1D6HNL9 View 3D Structure Click here
A0A1D6IP54 View 3D Structure Click here
A0A1D6P390 View 3D Structure Click here
A0A1D6Q2Q4 View 3D Structure Click here
A0A1D8PI93 View 3D Structure Click here
A0A1D8PIV7 View 3D Structure Click here
A0A1D8PMQ4 View 3D Structure Click here
A4HVN7 View 3D Structure Click here
A4HZT9 View 3D Structure Click here
A4IE38 View 3D Structure Click here
B0R1D0 View 3D Structure Click here
B4FBJ7 View 3D Structure Click here
B4FSF1 View 3D Structure Click here
B4FTV9 View 3D Structure Click here
B4G124 View 3D Structure Click here
B8A0A6 View 3D Structure Click here
C6TE07 View 3D Structure Click here
E9AG43 View 3D Structure Click here
E9AGB0 View 3D Structure Click here
G3V6W6 View 3D Structure Click here
I1JRA0 View 3D Structure Click here
I1K743 View 3D Structure Click here
I1LBA2 View 3D Structure Click here
I1LLZ2 View 3D Structure Click here
I1MXZ0 View 3D Structure Click here
K7MC85 View 3D Structure Click here
O04019 View 3D Structure Click here
O14126 View 3D Structure Click here
O16368 View 3D Structure Click here
O17071 View 3D Structure Click here
O18413 View 3D Structure Click here
O74445 View 3D Structure Click here
O74894 View 3D Structure Click here
O76371 View 3D Structure Click here
O88685 View 3D Structure Click here
P17980 View 3D Structure Click here
P33297 View 3D Structure Click here
P33298 View 3D Structure Click here
P34123 View 3D Structure Click here
P34124 View 3D Structure Click here
P36612 View 3D Structure Click here
P40327 View 3D Structure Click here
P41836 View 3D Structure Click here
P43686 View 3D Structure Click here
P46465 View 3D Structure Click here
P46466 View 3D Structure Click here
P46502 View 3D Structure Click here
P48601 View 3D Structure Click here
P53549 View 3D Structure Click here
P54775 View 3D Structure Click here
P62191 View 3D Structure Click here
P62192 View 3D Structure Click here
P62193 View 3D Structure Click here
P62195 View 3D Structure Click here
P62196 View 3D Structure Click here
P62198 View 3D Structure Click here
P62333 View 3D Structure Click here
P62334 View 3D Structure Click here
P9WQN5 View 3D Structure Click here
Q01939 View 3D Structure Click here
Q4D0B9 View 3D Structure Click here
Q4DHH6 View 3D Structure Click here
Q4DJA4 View 3D Structure Click here
Q4DTF6 View 3D Structure Click here
Q4DVH1 View 3D Structure Click here
Q4DW08 View 3D Structure Click here
Q4DZM5 View 3D Structure Click here
Q4E0K2 View 3D Structure Click here
Q54PJ1 View 3D Structure Click here
Q54PN7 View 3D Structure Click here
Q55BV5 View 3D Structure Click here
Q58576 View 3D Structure Click here
Q5A0L8 View 3D Structure Click here
Q5A6S2 View 3D Structure Click here
Q5SNC0 View 3D Structure Click here
Q63569 View 3D Structure Click here
Q63570 View 3D Structure Click here
Q653E3 View 3D Structure Click here
Q69Q32 View 3D Structure Click here
Q69X47 View 3D Structure Click here
Q6AZC1 View 3D Structure Click here
Q6DRD2 View 3D Structure Click here
Q6IQ72 View 3D Structure Click here
Q6Z875 View 3D Structure Click here
Q7GCH3 View 3D Structure Click here
Q8I1V1 View 3D Structure Click here
Q8IEQ1 View 3D Structure Click here
Q8II60 View 3D Structure Click here
Q8IJW0 View 3D Structure Click here
Q8MXF1 View 3D Structure Click here
Q8W422 View 3D Structure Click here
Q94BQ2 View 3D Structure Click here
Q9C5U3 View 3D Structure Click here
Q9FXT8 View 3D Structure Click here
Q9MAK9 View 3D Structure Click here
Q9SEI2 View 3D Structure Click here
Q9SEI3 View 3D Structure Click here
Q9SEI4 View 3D Structure Click here
Q9SL67 View 3D Structure Click here
Q9SZD4 View 3D Structure Click here
Q9V3V6 View 3D Structure Click here
Q9V405 View 3D Structure Click here
Q9VA54 View 3D Structure Click here
Q9VH79 View 3D Structure Click here
Q9VTQ9 View 3D Structure Click here
Q9W414 View 3D Structure Click here
Q9XTT9 View 3D Structure Click here