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80  structures 1525  species 0  interactions 18577  sequences 470  architectures

Family: Peptidase_C48 (PF02902)

Summary: Ulp1 protease family, C-terminal catalytic domain

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Ulp1 protease family, C-terminal catalytic domain Provide feedback

This domain contains the catalytic triad Cys-His-Asn.

Literature references

  1. Mossessova E, Lima CD; , Mol Cell 2000;5:865-876.: Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast. PUBMED:10882122 EPMC:10882122


Internal database links

External database links

This tab holds annotation information from the InterPro database.

InterPro entry IPR003653

This entry represents the C-terminal part of ubiquitin-like proteases that displays full proteolytic activity [ PUBMED:10882122 ].

Deubiquitinating enzymes (DUB) form a large family of cysteine protease that can deconjugate ubiquitin or ubiquitin-like proteins from ubiquitin-conjugated proteins. They can be classified in 3 families according to sequence homology [ PUBMED:10603300 , PUBMED:8982460 ]: ubiquitin carboxyl-terminal hydrolases (UCH), ubiquitin-specific processing proteases (UBP), and ubiquitin-like proteases (ULP) ( EC ) specific for deconjugating ubiquitin-like proteins. In contrast to the UBP pathway, which is very redundant (16 UBP enzymes in yeast), there is few ubiquitin-like protease (only one in yeast, ULP1).

ULP1 catalyses two critical functions in the SUMO/Smt3 pathway via its cysteine protease activity. ULP1 processes the Smt3 C-terminal sequence (-GGATY) to its mature form (-GG), and it deconjugates Smt3 from the lysine epsilon-amino group of the target protein [ PUBMED:10094048 ].

Crystal structure of yeast ULP1 bound to Smt3 [ PUBMED:10882122 ] revealed that the catalytic and interaction interface is situated in a shallow and narrow cleft where conserved residues recognise the Gly-Gly motif at the C-terminal extremity of Smt3 protein. Ulp1 adopts a novel architecture despite some structural similarity with other cysteine protease. The secondary structure is composed of seven alpha helices and seven beta strands. The catalytic domain includes the central alpha helix, beta-strands 4 to 6, and the catalytic triad (Cys-His-Asp).

Cysteine peptidases with a chymotrypsin-like fold are included in clan PA, which also includes serine peptidases. Cysteine peptidases that are N-terminal nucleophile hydrolases are included in clan PB. Cysteine peptidases with a tertiary structure similar to that of the serine-type aspartyl dipeptidase are included in clan PC. Cysteine peptidases with an intein-like fold are included in clan PD, which also includes asparagine lyases.

A cysteine peptidase is a proteolytic enzyme that hydrolyses a peptide bond using the thiol group of a cysteine residue as a nucleophile. Hydrolysis involves usually a catalytic triad consisting of the thiol group of the cysteine, the imidazolium ring of a histidine, and a third residue, usually asparagine or aspartic acid, to orientate and activate the imidazolium ring. In only one family of cysteine peptidases, is the role of the general base assigned to a residue other than a histidine: in peptidases from family C89 (acid ceramidase) an arginine is the general base. Cysteine peptidases can be grouped into fourteen different clans, with members of each clan possessing a tertiary fold unique to the clan. Four clans of cysteine peptidases share structural similarities with serine and threonine peptidases and asparagine lyases. From sequence similarities, cysteine peptidases can be clustered into over 80 different families [ PUBMED:11517925 ]. Clans CF, CM, CN, CO, CP and PD contain only one family.

Cysteine peptidases are often active at acidic pH and are therefore confined to acidic environments, such as the animal lysosome or plant vacuole. Cysteine peptidases can be endopeptidases, aminopeptidases, carboxypeptidases, dipeptidyl-peptidases or omega-peptidases. They are inhibited by thiol chelators such as iodoacetate, iodoacetic acid, N -ethylmaleimide or p -chloromercuribenzoate.

Clan CA includes proteins with a papain-like fold. There is a catalytic triad which occurs in the order: Cys/His/Asn (or Asp). A fourth residue, usually Gln, is important for stabilising the acyl intermediate that forms during catalysis, and this precedes the active site Cys. The fold consists of two subdomains with the active site between them. One subdomain consists of a bundle of helices, with the catalytic Cys at the end of one of them, and the other subdomain is a beta-barrel with the active site His and Asn (or Asp). There are over thirty families in the clan, and tertiary structures have been solved for members of most of these. Peptidases in clan CA are usually sensitive to the small molecule inhibitor E64, which is ineffective against peptidases from other clans of cysteine peptidases [ PUBMED:7044372 ].

Clan CD includes proteins with a caspase-like fold. Proteins in the clan have an alpha/beta/alpha sandwich structure. There is a catalytic dyad which occurs in the order His/Cys. The active site His occurs in a His-Gly motif and the active site Cys occurs in an Ala-Cys motif; both motifs are preceded by a block of hydrophobic residues [ PUBMED:9891971 ]. Specificity is predominantly directed towards residues that occupy the S1 binding pocket, so that caspases cleave aspartyl bonds, legumains cleave asparaginyl bonds, and gingipains cleave lysyl or arginyl bonds.

Clan CE includes proteins with an adenain-like fold. The fold consists of two subdomains with the active site between them. One domain is a bundle of helices, and the other a beta barrell. The subdomains are in the opposite order to those found in peptidases from clan CA, and this is reflected in the order of active site residues: His/Asn/Gln/Cys. This has prompted speculation that proteins in clans CA and CE are related, and that members of one clan are derived from a circular permutation of the structure of the other.

Clan CL includes proteins with a sortase B-like fold. Peptidases in the clan hydrolyse and transfer bacterial cell wall peptides. The fold shows a closed beta barrel decorated with helices with the active site at one end of the barrel [ PUBMED:14725770 ]. The active site consists of a His/Cys catalytic dyad.

Gene Ontology

The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.

Domain organisation

Below is a listing of the unique domain organisations or architectures in which this domain is found. More...

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Alignments

We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets and the UniProtKB sequence database. More...

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We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(27)
Full
(18577)
Representative proteomes UniProt
(31983)
RP15
(2833)
RP35
(8694)
RP55
(14177)
RP75
(20164)
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PP/heatmap 1            

1Cannot generate PP/Heatmap alignments for seeds; no PP data available

Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(27)
Full
(18577)
Representative proteomes UniProt
(31983)
RP15
(2833)
RP35
(8694)
RP55
(14177)
RP75
(20164)
Alignment:
Format:
Order:
Sequence:
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Download options

We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(27)
Full
(18577)
Representative proteomes UniProt
(31983)
RP15
(2833)
RP35
(8694)
RP55
(14177)
RP75
(20164)
Raw Stockholm Download   Download   Download   Download   Download   Download   Download  
Gzipped Download   Download   Download   Download   Download   Download   Download  

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

HMM logo

HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...

Trees

This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.

Note: You can also download the data file for the tree.

Curation and family details

This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.

Curation View help on the curation process

Seed source: Structural domain
Previous IDs: Ulp1_C;
Type: Domain
Sequence Ontology: SO:0000417
Author: Griffiths-Jones SR
Number in seed: 27
Number in full: 18577
Average length of the domain: 162.30 aa
Average identity of full alignment: 15 %
Average coverage of the sequence by the domain: 29.83 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 20.7 20.7
Trusted cut-off 20.7 20.7
Noise cut-off 20.6 20.6
Model length: 216
Family (HMM) version: 21
Download: download the raw HMM for this family

Species distribution

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Archea Archea Eukaryota Eukaryota
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Viroids Viroids Unclassified sequence Unclassified sequence

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Peptidase_C48 domain has been found. There are 80 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.

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AlphaFold Structure Predictions

The list of proteins below match this family and have AlphaFold predicted structures. Click on the protein accession to view the predicted structure.

Protein Predicted structure External Information
A0A0G2JVE7 View 3D Structure Click here
A0A0G2JZW2 View 3D Structure Click here
A0A0G2K935 View 3D Structure Click here
A0A0N7KH75 View 3D Structure Click here
A0A0N7KIU0 View 3D Structure Click here
A0A0N7KKG4 View 3D Structure Click here
A0A0N7KLF8 View 3D Structure Click here
A0A0P0UXP1 View 3D Structure Click here
A0A0P0V1F8 View 3D Structure Click here
A0A0P0V4Q3 View 3D Structure Click here
A0A0P0V7Z8 View 3D Structure Click here
A0A0P0VF79 View 3D Structure Click here
A0A0P0VHJ2 View 3D Structure Click here
A0A0P0VIX7 View 3D Structure Click here
A0A0P0VM85 View 3D Structure Click here
A0A0P0VPS2 View 3D Structure Click here
A0A0P0VXV0 View 3D Structure Click here
A0A0P0W0V2 View 3D Structure Click here
A0A0P0W7P1 View 3D Structure Click here
A0A0P0W8C6 View 3D Structure Click here
A0A0P0WFC2 View 3D Structure Click here
A0A0P0WJ34 View 3D Structure Click here
A0A0P0WJV9 View 3D Structure Click here
A0A0P0WKJ2 View 3D Structure Click here
A0A0P0WMB6 View 3D Structure Click here
A0A0P0WS70 View 3D Structure Click here
A0A0P0WWQ2 View 3D Structure Click here
A0A0P0WWS1 View 3D Structure Click here
A0A0P0WX19 View 3D Structure Click here
A0A0P0X4A4 View 3D Structure Click here
A0A0P0X517 View 3D Structure Click here
A0A0P0X6U4 View 3D Structure Click here
A0A0P0XJC0 View 3D Structure Click here
A0A0P0XJN7 View 3D Structure Click here
A0A0P0XL95 View 3D Structure Click here
A0A0P0XTL3 View 3D Structure Click here
A0A0P0XYS5 View 3D Structure Click here
A0A0P0Y015 View 3D Structure Click here
A0A0P0Y0S2 View 3D Structure Click here
A0A0P0Y1M1 View 3D Structure Click here
A0A0P0Y578 View 3D Structure Click here
A0A0P0Y5X3 View 3D Structure Click here
A0A0P0Y5Z5 View 3D Structure Click here
A0A0P0Y6T8 View 3D Structure Click here
A0A0P0YBA3 View 3D Structure Click here
A0A0R0ELT0 View 3D Structure Click here
A0A0R0FWE9 View 3D Structure Click here
A0A0R0H491 View 3D Structure Click here
A0A0R0HSA6 View 3D Structure Click here
A0A0R0IU09 View 3D Structure Click here
A0A0R0J008 View 3D Structure Click here
A0A0R0JI74 View 3D Structure Click here
A0A0R0KZB1 View 3D Structure Click here
A0A0R4ILS0 View 3D Structure Click here
A0A173G2S1 View 3D Structure Click here
A0A1D6E2H9 View 3D Structure Click here
A0A1D6EBC6 View 3D Structure Click here
A0A1D6EBT8 View 3D Structure Click here
A0A1D6ED96 View 3D Structure Click here
A0A1D6EEY5 View 3D Structure Click here
A0A1D6EHI1 View 3D Structure Click here
A0A1D6EM19 View 3D Structure Click here
A0A1D6ENL9 View 3D Structure Click here
A0A1D6ERY9 View 3D Structure Click here
A0A1D6ESP5 View 3D Structure Click here
A0A1D6EST4 View 3D Structure Click here
A0A1D6ETI8 View 3D Structure Click here
A0A1D6EU15 View 3D Structure Click here
A0A1D6F491 View 3D Structure Click here
A0A1D6F491 View 3D Structure Click here
A0A1D6F4W7 View 3D Structure Click here
A0A1D6F782 View 3D Structure Click here
A0A1D6FF09 View 3D Structure Click here
A0A1D6FFR6 View 3D Structure Click here
A0A1D6FI82 View 3D Structure Click here
A0A1D6FIA8 View 3D Structure Click here
A0A1D6FIB6 View 3D Structure Click here
A0A1D6FL42 View 3D Structure Click here
A0A1D6FP47 View 3D Structure Click here
A0A1D6FQN0 View 3D Structure Click here
A0A1D6FVF6 View 3D Structure Click here
A0A1D6FVM4 View 3D Structure Click here
A0A1D6G6Q1 View 3D Structure Click here
A0A1D6G870 View 3D Structure Click here
A0A1D6G875 View 3D Structure Click here
A0A1D6G891 View 3D Structure Click here
A0A1D6G9X8 View 3D Structure Click here
A0A1D6GCJ0 View 3D Structure Click here
A0A1D6GDM1 View 3D Structure Click here
A0A1D6GE36 View 3D Structure Click here
A0A1D6GKC4 View 3D Structure Click here
A0A1D6GRJ0 View 3D Structure Click here
A0A1D6GTQ3 View 3D Structure Click here
A0A1D6GUU1 View 3D Structure Click here
A0A1D6GZJ6 View 3D Structure Click here
A0A1D6H278 View 3D Structure Click here
A0A1D6H362 View 3D Structure Click here
A0A1D6H561 View 3D Structure Click here
A0A1D6H6A9 View 3D Structure Click here
A0A1D6H8S3 View 3D Structure Click here
A0A1D6H9A3 View 3D Structure Click here
A0A1D6H9Z5 View 3D Structure Click here
A0A1D6HAG8 View 3D Structure Click here
A0A1D6HBI2 View 3D Structure Click here
A0A1D6HFU2 View 3D Structure Click here
A0A1D6HQF8 View 3D Structure Click here
A0A1D6HUC2 View 3D Structure Click here
A0A1D6HUD9 View 3D Structure Click here
A0A1D6HZA7 View 3D Structure Click here
A0A1D6HZE1 View 3D Structure Click here
A0A1D6I0D6 View 3D Structure Click here
A0A1D6I0M4 View 3D Structure Click here
A0A1D6I0S5 View 3D Structure Click here
A0A1D6I3C0 View 3D Structure Click here
A0A1D6I434 View 3D Structure Click here
A0A1D6I6S0 View 3D Structure Click here
A0A1D6I9D7 View 3D Structure Click here
A0A1D6IBP0 View 3D Structure Click here
A0A1D6ITF9 View 3D Structure Click here
A0A1D6IVE5 View 3D Structure Click here
A0A1D6IXP4 View 3D Structure Click here
A0A1D6J1K6 View 3D Structure Click here
A0A1D6J595 View 3D Structure Click here
A0A1D6J7F3 View 3D Structure Click here
A0A1D6J7F7 View 3D Structure Click here
A0A1D6JAX5 View 3D Structure Click here
A0A1D6JFJ4 View 3D Structure Click here
A0A1D6JRM1 View 3D Structure Click here
A0A1D6JU44 View 3D Structure Click here
A0A1D6JZN9 View 3D Structure Click here
A0A1D6K0A4 View 3D Structure Click here
A0A1D6K177 View 3D Structure Click here
A0A1D6K2P0 View 3D Structure Click here
A0A1D6K8P8 View 3D Structure Click here
A0A1D6K996 View 3D Structure Click here
A0A1D6KBX8 View 3D Structure Click here
A0A1D6KCC1 View 3D Structure Click here
A0A1D6KDC3 View 3D Structure Click here
A0A1D6KFX9 View 3D Structure Click here
A0A1D6KGD6 View 3D Structure Click here
A0A1D6KKN8 View 3D Structure Click here
A0A1D6KLG2 View 3D Structure Click here
A0A1D6KQI9 View 3D Structure Click here
A0A1D6KRV4 View 3D Structure Click here
A0A1D6KUJ5 View 3D Structure Click here
A0A1D6KVU8 View 3D Structure Click here
A0A1D6L0W7 View 3D Structure Click here
A0A1D6L0W7 View 3D Structure Click here
A0A1D6L5B8 View 3D Structure Click here
A0A1D6L6H6 View 3D Structure Click here
A0A1D6LCK6 View 3D Structure Click here
A0A1D6LE65 View 3D Structure Click here
A0A1D6LG53 View 3D Structure Click here
A0A1D6LGX0 View 3D Structure Click here
A0A1D6LI15 View 3D Structure Click here
A0A1D6LL57 View 3D Structure Click here
A0A1D6LLR1 View 3D Structure Click here
A0A1D6LP06 View 3D Structure Click here
A0A1D6LPC5 View 3D Structure Click here
A0A1D6LXF6 View 3D Structure Click here
A0A1D6LYJ6 View 3D Structure Click here
A0A1D6LZ85 View 3D Structure Click here
A0A1D6M2R0 View 3D Structure Click here
A0A1D6M2S5 View 3D Structure Click here
A0A1D6MB49 View 3D Structure Click here
A0A1D6MJB3 View 3D Structure Click here
A0A1D6MJB5 View 3D Structure Click here
A0A1D6MWW2 View 3D Structure Click here
A0A1D6MWW6 View 3D Structure Click here
A0A1D6MXQ1 View 3D Structure Click here
A0A1D6NBY4 View 3D Structure Click here
A0A1D6ND91 View 3D Structure Click here
A0A1D6NDQ9 View 3D Structure Click here
A0A1D6NEM9 View 3D Structure Click here
A0A1D6NGJ0 View 3D Structure Click here
A0A1D6NHJ0 View 3D Structure Click here
A0A1D6NI49 View 3D Structure Click here
A0A1D6NKH4 View 3D Structure Click here
A0A1D6NMW3 View 3D Structure Click here
A0A1D6NQW7 View 3D Structure Click here
A0A1D6NTA0 View 3D Structure Click here
A0A1D6NVB3 View 3D Structure Click here
A0A1D6NVM4 View 3D Structure Click here
A0A1D6NYA2 View 3D Structure Click here
A0A1D6NYR1 View 3D Structure Click here
A0A1D6NZK7 View 3D Structure Click here
A0A1D6P0E2 View 3D Structure Click here
A0A1D6P1K8 View 3D Structure Click here
A0A1D6P1V8 View 3D Structure Click here
A0A1D6P2J1 View 3D Structure Click here
A0A1D6P4L3 View 3D Structure Click here
A0A1D6PAM6 View 3D Structure Click here
A0A1D6PBW5 View 3D Structure Click here
A0A1D6PBY7 View 3D Structure Click here
A0A1D6PC39 View 3D Structure Click here
A0A1D6PE46 View 3D Structure Click here
A0A1D6PFM8 View 3D Structure Click here
A0A1D6PUE5 View 3D Structure Click here
A0A1D6PX39 View 3D Structure Click here
A0A1D6PY96 View 3D Structure Click here
A0A1D6Q0T4 View 3D Structure Click here
A0A1D6Q6Y6 View 3D Structure Click here
A0A1D6Q756 View 3D Structure Click here
A0A1D6QBS7 View 3D Structure Click here
A0A1D6QIT4 View 3D Structure Click here
A0A1D6QJ01 View 3D Structure Click here
A0A1D6QJD6 View 3D Structure Click here
A0A1D6QK89 View 3D Structure Click here
A0A1D6QNJ9 View 3D Structure Click here
A0A1D6QNZ4 View 3D Structure Click here
A0A1D6QRU3 View 3D Structure Click here
A0A1D6QTB7 View 3D Structure Click here
A0A1D6QVA6 View 3D Structure Click here
A0A1D8PIW0 View 3D Structure Click here
A0A1D8PSK4 View 3D Structure Click here
A0A1P8B1I0 View 3D Structure Click here
A0A1Q0XFF3 View 3D Structure Click here
A0A1Q0XH88 View 3D Structure Click here
A0A1Q0YD05 View 3D Structure Click here
A0A1Q0YIL8 View 3D Structure Click here
A0A1Q0YP48 View 3D Structure Click here
A0A1Q0Z1Z8 View 3D Structure Click here
A0A1Q0ZJE6 View 3D Structure Click here
A0A1Q1A0T8 View 3D Structure Click here
A0A1Q1AIH6 View 3D Structure Click here
A0A1Q1C983 View 3D Structure Click here
A0A1R3LE38 View 3D Structure Click here
A0A1R3LPD0 View 3D Structure Click here
A0A1R3LYP9 View 3D Structure Click here
A0A1R3MV48 View 3D Structure Click here
A0A1R3N3K0 View 3D Structure Click here
A0A1R3NIP9 View 3D Structure Click here
A0A1R3NKI4 View 3D Structure Click here
A0A1R3P7Y6 View 3D Structure Click here
A0A1R3P8L3 View 3D Structure Click here
A0A1R3PHJ6 View 3D Structure Click here
A0A1R3PMF7 View 3D Structure Click here
A0A1R3QGA7 View 3D Structure Click here
A0A1R3QJ20 View 3D Structure Click here
A0A1R3QMN6 View 3D Structure Click here
A0A1R3QPQ5 View 3D Structure Click here
A0A1R3QZ64 View 3D Structure Click here
A0A1X7YI02 View 3D Structure Click here
A0A1X7YIE3 View 3D Structure Click here
A0A2R8QQR0 View 3D Structure Click here
A0A368UHJ8 View 3D Structure Click here
A2BEN4 View 3D Structure Click here
A4I2D5 View 3D Structure Click here
A4I2D5 View 3D Structure Click here
B4FHT9 View 3D Structure Click here
B7E6X2 View 3D Structure Click here
C0HDT6 View 3D Structure Click here
C6TMM4 View 3D Structure Click here
D3Z741 View 3D Structure Click here
D3ZF42 View 3D Structure Click here
D4A2S8 View 3D Structure Click here
E1JH43 View 3D Structure Click here
E7F9B8 View 3D Structure Click here
E7F9K9 View 3D Structure Click here
E9PXF3 View 3D Structure Click here
F1LTK7 View 3D Structure Click here
F1LU78 View 3D Structure Click here
F1LU78 View 3D Structure Click here
F1LVT6 View 3D Structure Click here
F1M0I3 View 3D Structure Click here
F1M224 View 3D Structure Click here
F1Q8C1 View 3D Structure Click here
F1Q9H5 View 3D Structure Click here
F1QS17 View 3D Structure Click here
F4I3A8 View 3D Structure Click here
F4IK96 View 3D Structure Click here
F4IK98 View 3D Structure Click here
F4JF18 View 3D Structure Click here
F6NJF2 View 3D Structure Click here
G3V7S5 View 3D Structure Click here
G3X9P9 View 3D Structure Click here
I1JXG7 View 3D Structure Click here
I1KMY1 View 3D Structure Click here
I1L0Z6 View 3D Structure Click here
I1MRJ1 View 3D Structure Click here
K7DYE7 View 3D Structure Click here
K7KJ35 View 3D Structure Click here
K7LL14 View 3D Structure Click here
K7MBE6 View 3D Structure Click here
K7MN81 View 3D Structure Click here
K7MRZ4 View 3D Structure Click here
K7MV68 View 3D Structure Click here
K7MV81 View 3D Structure Click here
K7MV83 View 3D Structure Click here
K7TZS3 View 3D Structure Click here
K7VGU4 View 3D Structure Click here
M0R6C0 View 3D Structure Click here
O13612 View 3D Structure Click here
O13769 View 3D Structure Click here
O42957 View 3D Structure Click here
O42980 View 3D Structure Click here
O44984 View 3D Structure Click here
O65278 View 3D Structure Click here
P40537 View 3D Structure Click here
P59110 View 3D Structure Click here
Q02724 View 3D Structure Click here
Q08CI6 View 3D Structure Click here
Q09275 View 3D Structure Click here
Q09353 View 3D Structure Click here
Q0WKV8 View 3D Structure Click here
Q10LL2 View 3D Structure Click here
Q1L9B2 View 3D Structure Click here
Q23238 View 3D Structure Click here
Q2PS26 View 3D Structure Click here
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