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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A0A0G2KYI1_DANRE (A0A0G2KYI1)

Summary

This is the summary of UniProt entry A0A0G2KYI1_DANRE (A0A0G2KYI1).

Description: Sodium channel protein {ECO:0000256|RuleBase:RU361132}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 1954 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 32 53
transmembrane n/a 125 148
Pfam Ion_trans 128 427
transmembrane n/a 193 212
transmembrane n/a 224 245
transmembrane n/a 251 271
low_complexity n/a 309 319
transmembrane n/a 393 420
coiled_coil n/a 417 458
low_complexity n/a 443 457
disorder n/a 473 500
Pfam Na_trans_cytopl 509 669
disorder n/a 539 563
low_complexity n/a 569 585
disorder n/a 602 608
low_complexity n/a 605 616
disorder n/a 617 624
disorder n/a 626 627
disorder n/a 634 640
Pfam Ion_trans 705 939
transmembrane n/a 707 725
transmembrane n/a 737 760
transmembrane n/a 772 796
low_complexity n/a 793 805
transmembrane n/a 817 845
low_complexity n/a 833 845
transmembrane n/a 875 893
transmembrane n/a 905 930
low_complexity n/a 918 940
Pfam Na_trans_assoc 944 1143
low_complexity n/a 977 988
low_complexity n/a 982 995
disorder n/a 1003 1103
low_complexity n/a 1039 1070
low_complexity n/a 1092 1106
Pfam Ion_trans 1147 1421
transmembrane n/a 1148 1167
transmembrane n/a 1188 1207
transmembrane n/a 1213 1235
low_complexity n/a 1244 1259
transmembrane n/a 1256 1274
transmembrane n/a 1280 1300
transmembrane n/a 1387 1410
low_complexity n/a 1444 1456
Pfam Ion_trans 1467 1724
transmembrane n/a 1469 1487
low_complexity n/a 1472 1486
transmembrane n/a 1499 1521
transmembrane n/a 1533 1552
low_complexity n/a 1537 1548
low_complexity n/a 1565 1584
transmembrane n/a 1573 1594
transmembrane n/a 1600 1622
disorder n/a 1668 1678
transmembrane n/a 1690 1713
disorder n/a 1814 1816
disorder n/a 1832 1834
disorder n/a 1874 1887
disorder n/a 1903 1904
disorder n/a 1906 1908
disorder n/a 1910 1915
disorder n/a 1938 1944
disorder n/a 1950 1951

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0A0G2KYI1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAAILFPPGP DSLHRFTRES LAGIEQRIAE EEARNAKRYQ EDRGDVEPPK
50
51
PRADLEAGKQ LPRIFGDIPS ALVGVPLEDI DPFYFQNRRT FIVLNKGKAI
100
101
FRFSATSALY IFSPFHPIRR ASIRILVHSL FSLFIMCTIL TNCCFMAMSE
150
151
PAQWAKYVEY TFTGIYTFES LIKILARGFC IGPFTFLRDP WNWLDFSVIL
200
201
MAYVTEFVDL GNVSALRTFR VLRALKTISV IPGLKTIVGA LIQSVKKLAD
250
251
VMILTVFCLS VFALIGLQLF MGNLRQKCVR SASQCLNTTL PTYNNSTFIC
300
301
NNRSWASLEE FFNNEENFFK VEGAKDALIC GNASDAGKCP DGFECLKTGR
350
351
NPNYGYTSFD TFGWAFLSLF RLMTQDYWEN LYHHTLRSAG KAYMVFFVVV
400
401
IFLGSFYLVN LILAVVAMAY EEQNQATIAE ALQKEQEFQL AMEQLKKEQQ
450
451
AAQKAQETES ILTADVSPFS TQDKAKLERR KSSRPLSEGT GEDKPAKLDP
500
501
IEGIKQTHSL LVRTLSLRAR RESAVSIFNF RPVNKDSELD FADDEFSNHG
550
551
DSDSRGGALA LPWSRRRTSA QSSCSHSSQF FFPSFNINGK LMVAVEQNGI
600
601
SSQGPLTPMT PLTPLPACTM EKLKEESGQN SSNELSSMLL PQLPPEGRDR
650
651
ALSATSYITD AMEELEEAQQ KCHPCWYVFA HKYLVWTCSP RWLKVKEWVK
700
701
IMVMDPFLDL AITICIVLNT LFMALEHYPM TDEFNRMLSV GNLVFTGIFT
750
751
AEMVLKIIAL DPYYYFQQGW NIFDSLIVSL SLMELGLSNV EGLSVLRSFR
800
801
LLRVFKLAKS WPTLNTLIKI IGNSVGALGN LTLVLAIIVF IFAVVGMQLF
850
851
GKNYDLCVCK ISKDCTLPRW HMKDFFHSFL IVFRVLCGEW IETMWDCMEV
900
901
AGQPLCILVF MLVMVIGNLV VLNLFLALLL SSFSADNLSA PDEDGEMNNL
950
951
QIAIARIQRG MLWLRQALCD FFNGNFKRRR QKAKEAKAML KLKRLSQQAH
1000
1001
WAEGNGTAGV IERSSGAGSG EDDSYMTNPN LTISVPIAPG ESDVEFPEEE
1050
1051
DEEEDEEEEA SASSDEEPEP CKPRDDTSLS EGSTIDLRKP GEEEDEYSEM
1100
1101
AEEAMDPENC FPDVCVRHFK CCDINTSEGL GRAWWRLRKT CYQIVEHSWF
1150
1151
ETFIIFMILL SSGALAFEDI YIDQRKVVKV ILEYADKIFT YIFILEMSLK
1200
1201
WIAYGFRKYF TNYWCWLDFL IVDVSLVSLV ANTLGYSDFA AIKSLRTLRA
1250
1251
LRPLRALSRF EGMRVVVNAL IGAIPSIMNV LLVCLIFWLI FSIMGVNLFA
1300
1301
GKFGRCVNRT GFIYNSSDIN NRSECLEMNS TQYYWTKVKV NFDNVGAGYL
1350
1351
ALLQVATFKG WMEIMYAAVD SRAVEEQPIK ENSLYMYLYF VIFIIFGSFF
1400
1401
TLNLFIGVII DNFNQQKRKL GGQDIFMTEE QKKYYNAMKK LGSKKPQKPI
1450
1451
PRPPNPVQGF FFDLVSKQAF DILIMLLIIL NMVTMMVETD EQSPSIKHIL
1500
1501
DCINLVFIVI FTSECILKII ALRCYFFTVS WNIFDFVVVI LSIVGIVLAD
1550
1551
IIEKYFVSPT LFRVIRLARI GRILRLIRGA KGIRTLLFAL MMSLPALFNI
1600
1601
GLLLFLVMFI YAIFGMANFA YVKKQGGIDD MFNFETFGNS MICLFQITTS
1650
1651
AGWDNLLSPI LNTPPEECDP EIPHTGTNAR GNCGNPSVGI TFFVTYIIIS
1700
1701
FLIVVNMYIA IILENFSVAT EESTEPLSED DFEMFYEVWE KFDPEATQFI
1750
1751
EYLKLSDFAD TLSEPLRIGK PNKIKLISMD LPMVSGDKIH CLDILFAFTK
1800
1801
RVLGESGEMD ALKQQMEEKF MMANPSKISY EPITTTLRRK QEEVSAIMIQ
1850
1851
RSYRRHLIRR QLKQASLLYR QMTMPDADKA GDSSPESQGL IVSMIMENYA
1900
1901
TEAEITISAT SSPPSYDSVT RATSEIFHAL IPEETNEILS EHLADAEKES
1950
1951
ETFL                                                  
1954
 

Show the unformatted sequence.

Checksums:
CRC64:2CD5E43C07E7ACB1
MD5:ef701d29bdf698679dbafe7f2cb3ee1f

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;