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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A0A0R4IQG1_DANRE (A0A0R4IQG1)

Summary

This is the summary of UniProt entry A0A0R4IQG1_DANRE (A0A0R4IQG1).

Description: 3-hydroxy-3-methylglutaryl coenzyme A synthase {ECO:0000256|ARBA:ARBA00014137, ECO:0000256|RuleBase:RU364071}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 519 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HMG_CoA_synt_N 13 186
Pfam HMG_CoA_synt_C 187 470
disorder n/a 424 426
disorder n/a 436 437
disorder n/a 465 487
disorder n/a 489 490
disorder n/a 492 519

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0A0R4IQG1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPGSLPAICE SMWPKDVGII AMEVYVPSQY VDQAELEEYD GVGAGKYTVG
50
51
LGQARMGFCS DREDINSLCL TVVQRLMERN GLSYESVGRL EVGTETIIDK
100
101
SKSTKTVLMQ LFEESGNTDV EGVDTTNACY GGTAALFNAV NWVESSSWDG
150
151
RYALVVAGDI AVYATGSARP TGGAGAVAML VGPNAPLAFE RGLRGTHMQH
200
201
AYDFYKPDMV SEYPVVDGKL SIQCYLSALD QCYSVYKNKI HARWQREGTE
250
251
GRCSLEDFGF MVFHSPYCKL VQKSLARLML NDFLCHPSPN MESGPFSGLE
300
301
AFRDVKIEDT YFDRDVEKAF MKASSELFDD KTKASLLISN QNGNMYTPSV
350
351
YGCLASVLAQ HTPQQLAGQR IGVFSYGSGF AATLYSIKVT QDGTPGSALD
400
401
KLVSSLCDLP ARLDSRQKVS PGVFAETMKL REETHHLANY IPQGSVDELF
450
451
PGTWYLTRVD EKHRRQYARR SMNDDRPLEA GLVSSSMAAE HIPSPLKKMP
500
501
RIPTTTAGPE VVVMSNGDH                                  
519
 

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Checksums:
CRC64:A1355E795DD3BA48
MD5:46194b103ece52693ab5a01f414c037a

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;