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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A0A1D8PKY7_CANAL (A0A1D8PKY7)

Summary

This is the summary of UniProt entry A0A1D8PKY7_CANAL (A0A1D8PKY7).

Description: Histidine biosynthesis trifunctional protein {ECO:0000256|PIRNR:PIRNR001257} Phosphoribosyl-AMP cyclohydrolase {ECO:0000256|PIRNR:PIRNR001257} Phosphoribosyl-ATP pyrophosphohydrolase {ECO:0000256|PIRNR:PIRNR001257} Histidinol dehydrogenase {ECO:0000256|PIRNR:PIRNR001257}
Source organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (NCBI taxonomy ID 237561)
Length: 838 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam PRA-CH 206 282
Pfam PRA-PH 293 376
disorder n/a 297 298
coiled_coil n/a 317 344
low_complexity n/a 319 338
disorder n/a 386 387
Pfam Histidinol_dh 416 831
disorder n/a 831 834

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0A1D8PKY7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MIFPILPVIS SPEDKQSIDE FSLVGQVLFP IESVSPKKHF IHQFPHDLDI
50
51
FVNAIDNATT DQIVELLNVG IKQVFVNEKQ YHDAIEAGSP SSRFVVAVDV
100
101
PSTELLTSEA SFVTSKPFSE SDLKKYNANE NRVIYIESNF TQDGAIELAK
150
151
NYVPVIPSTK LTVKREEENK ISISAVFVST LTTDRPDGLY TTLITTPSPS
200
201
YTALGIVYSS KDSIIAAIEE KVGVYQSRKR RDELWYKGKT SGATQKLVKL
250
251
SKDCDSHVIQ FMVEPRTGYG FCHRETKFTC FGDDIADSPA RGLPKLDSTL
300
301
QDRLENAPEV SYTKRLFDDE KLLIAKLKEE LDELIEAKSK EEIAWECADL
350
351
VYFAMVWCIK HGVRLADIEK NLDVKSLKVS RRKGDAKPQY QEAPVNSSYK
400
401
LEIVSVDDAA AVERAMTRPV QKTADIMKLV LPIIEKVKSD GDKALIELTS
450
451
KFDGVKLDAP VLQAPFPADL MDISEEMKAA IDLSMQNIEK FHAAQLPKEK
500
501
VMTVETSPGV YCSRFAKPIE NVGLYVPGGT AVLPSTAMML GVPAKVAGCK
550
551
NIIVASPPSR ATGKLTPEVV YVAHKLGAKC IVMAGGAQAV TAMAYGTESV
600
601
LKCDKILGPG NQFVTAAKMY VQNDTQALCS IDMPAGPSEV LVIADSNADA
650
651
DFVASDLLSQ AEHGVDSQVI LIGVGLSDEK LNEFQAAVER QAKVLPRKDI
700
701
VAKCLAHSYI LLAKTYKEAF DLSNQYAPEH LILQIDDAPS YVPDSIENAG
750
751
SVFVGALSPE SCGDYSSGTN HTLPTYGYAR QYSGVNTATF QKFITSQEVT
800
801
EKGLQNIGKA VMELARVEGL EAHRRAVEIR MERMAETK             
838
 

Show the unformatted sequence.

Checksums:
CRC64:973C93EF50A56738
MD5:220f8645a7cb679c806809b55c52f039

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;