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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A2CE51_DANRE (A2CE51)

Summary

This is the summary of UniProt entry A2CE51_DANRE (A2CE51).

Description: Eukaryotic translation elongation factor 2,-like 2 {ECO:0000313|Ensembl:ENSDARP00000051080}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 861 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam GTP_EFTU 17 363
low_complexity n/a 127 137
low_complexity n/a 234 246
disorder n/a 247 251
coiled_coil n/a 312 332
Pfam GTP_EFTU_D2 412 489
Pfam EFG_III 504 570
disorder n/a 592 594
disorder n/a 618 619
Pfam EFG_IV 623 740
Pfam EFG_C 742 831
disorder n/a 834 835

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A2CE51. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVNFTVDQIR EIMDKKSNIR NMSVIAHVDH GKSTLTDSLV CKAGIIASAR
50
51
AGETRFTDTR KDEQERCITI KSTAISLYYE LSENDSAFIK QCKDGSGFLI
100
101
NLIDSPGHVD FSSEVTAALR VTDGALVVVD CVSGVCVQTE TVLRQAIAER
150
151
IKPVLMMNKM DRALLELQLE PDELFQTFQR IVENVNVIIS TYGEGEHGPM
200
201
GNIMVDPVIG TVGFGSGLHG WAFTLKQFAE MYVAKFAAKG DKKKGDLPPA
250
251
ERAKKVEEMM KKLWGDKYFD PSCGKFSKTA NNADGKKLPR TFCQLVLDPI
300
301
FKVFDAIMNF KKEETQKLIE KLEVKLDAED KEKEGKPLLK AVMRRWLPAG
350
351
DALLQMITIH LPSPVTAQRY RCELLYEGPG DDEAAMGIKN CDPKAPLMMY
400
401
ISKMVPTTDK GRFYAFGRVF SGIVSTGQKV RIMGPNFTPG KKEDLYLKPI
450
451
QRTILMMGRY VEPIEDVPCG NIVGLVGVDQ FLVKTGTITT FENSHNMRVM
500
501
KFSVSPVVRV AVEAKNPADL PKLVEGLKRL AKSDPMVQCI IEESGEHIVA
550
551
GAGELHLEIC LKDLEEDHAC IPLKKSDPVV SYRETVSDES DQVCLSKSPN
600
601
KHNRLYMKSR PFPDGLAEDI DKGDVSSRQE LKLRARYLAE KYEWEVAEAR
650
651
KIWCFGPDGT GPNILVDITK GVQYLNEIKD SVVAGFQWAT KEGALCEENM
700
701
RAVRFDIHDV TLHADAIHRG GGQIIPTARR VLYASVLTAQ PRLMEPIYLV
750
751
EIQCPEQVVG GIYGVLNRKR GHVFEESQVA GTPIFVVKAY LPVNESFGFT
800
801
ADLRSNTGGQ AFPQCVFDHW QILPGDPYDV NSKPSQIVAD TRKRKGLKEG
850
851
IPALDNFLDK L                                          
861
 

Show the unformatted sequence.

Checksums:
CRC64:943EFB86B8E4883B
MD5:ab95ea83b6395f6e3ddaddfe881add29

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;