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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A2CEB0_DANRE (A2CEB0)

Summary

This is the summary of UniProt entry A2CEB0_DANRE (A2CEB0).

Description: Polymerase (DNA directed) iota {ECO:0000313|Ensembl:ENSDARP00000041370}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 710 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 19
low_complexity n/a 2 13
Pfam IMS 42 216
disorder n/a 294 295
disorder n/a 297 313
Pfam IMS_C 304 431
coiled_coil n/a 316 336
low_complexity n/a 318 335
disorder n/a 371 377
low_complexity n/a 421 431
disorder n/a 430 431
disorder n/a 435 436
disorder n/a 440 441
disorder n/a 443 449
disorder n/a 472 518
low_complexity n/a 480 491
disorder n/a 526 528
disorder n/a 543 544
disorder n/a 554 599
disorder n/a 601 615
disorder n/a 618 653
disorder n/a 662 665
disorder n/a 667 703

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A2CEB0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDSDEEEDNN DWERSLESDI LETEGSSTDR VSLTSQRVIL HFDLDCFYAQ
50
51
VEMIRNPALR TKPLGIQQKY IIVTSNYVAR ELGVNKLMSV TDAVEKCPQL
100
101
VLVKGEDLTH YREMSYKVTE LLMSYCPLVE RLGFDENFMD VTEMVEKRIK
150
151
ETRISDLSFN GHVYNHESVV VDEENIRLAV GSVIAAEMRQ AIFSTLGLTG
200
201
CAGVASNKLL AKLVSGSFKP NQQTTLLPHS TAELMSSLTG LIKVPGIGYK
250
251
TREKLKALGL VNVRDLQLYP LSDLVKEFGE MNAKRIQNLA CGIDDSPVTP
300
301
AGPPQSLSDE DSFKKMSTLE EVLKKIEELL INLTERMHKD GRQPHTLRLT
350
351
IRKYTVTNRW FNRESRQCPI PNHTGLKITG GSSEAVPQLL SLSMKLFHKM
400
401
VDPHQPFHLT LLNVCFSNLQ AKSSSKSSIA SFFTHKSPST TQIPSQQVDS
450
451
DLCESVATSH FTQADVLHKN DKAWKPVKNT SISPTQTQST SVNPKSSLSP
500
501
RQPVSEHSQH ANINIRPPCL SSAPKKTLHF KLPPNVDADV FKLLPEHIQM
550
551
ELMSSFKKGD SVYRPADTED VDPEHQPTFA SRQPKTPKPC ESAVNVCTNS
600
601
ASNPHELSQN FSSPQSIPEF SSELVMVTES DDIPHSTQAI QPEVPANVDP
650
651
YVFSQLPADV QRELLTEWRQ QRPVLKIPSK HSHKSSNSRD RKTSTKGSQC
700
701
NNILKYFKPN                                            
710
 

Show the unformatted sequence.

Checksums:
CRC64:C4E9DEC4D174AB4E
MD5:ff4fb5458b4ae2a3fff9278c4742e675

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;