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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A4HWE1_LEIIN (A4HWE1)

Summary

This is the summary of UniProt entry A4HWE1_LEIIN (A4HWE1).

Description: Asparaginase {ECO:0000256|ARBA:ARBA00012920}
Source organism: Leishmania infantum (NCBI taxonomy ID 5671)
Length: 398 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 6 21
low_complexity n/a 7 23
Pfam Asparaginase 29 220
low_complexity n/a 58 71
Pfam Asparaginase_C 165 380
low_complexity n/a 296 307

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A4HWE1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEAGIEATAT PAALTQPPAA PRPGRNTRRI LVLYLGGTIG MKKNAAGALE
50
51
PVAGYLTEQM REMRELRESS EIAPFDIIEY AELLDSSDMN AADYCRIAAD
100
101
VQVHYDEYDG FLIAHGTDTM HYTASALSFL LCNLGKPVIV TGAMVALAEP
150
151
YNDARRNVVI GMMIASNPKI CEVCIFFNDS LFRGNRCNKV YHTYGAFRSL
200
201
NYPALGVVGA TDFVLKDEHL LPQPMGALKI MSDMRGRVGC YPIDPEADVD
250
251
TFVALLEQKR PRSSPCAFSV TAAPSTDDSD GAQKPLLDAV LLSLNGVGSV
300
301
QGVVAQQLRR IVAVAHKHNI VVCAVARDIS GTLNPSEVQR LHAISPEIVY
350
351
LNDMCASAAE VKLMYLFGKG LSPAKVAAAM TQNLRGEITP LLEVHAKL  
398
 

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Checksums:
CRC64:3D0160F91D44006A
MD5:b2c923d015987f5d1151552b4e9d1a94

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;