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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A4HX31_LEIIN (A4HX31)

Summary

This is the summary of UniProt entry A4HX31_LEIIN (A4HX31).

Description: DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418}
Source organism: Leishmania infantum (NCBI taxonomy ID 5671)
Length: 1810 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 117 118
disorder n/a 123 132
disorder n/a 194 203
disorder n/a 233 244
low_complexity n/a 238 261
disorder n/a 246 247
disorder n/a 251 254
low_complexity n/a 310 324
disorder n/a 331 336
low_complexity n/a 403 412
disorder n/a 459 463
Pfam RNA_pol_Rpb1_2 503 684
Pfam RNA_pol_Rpb1_3 687 893
disorder n/a 787 788
disorder n/a 792 794
disorder n/a 800 807
disorder n/a 811 819
disorder n/a 907 908
Pfam RNA_pol_Rpb1_4 924 1008
Pfam RNA_pol_Rpb1_5 1015 1748
disorder n/a 1110 1137
low_complexity n/a 1116 1123
low_complexity n/a 1131 1155
coiled_coil n/a 1134 1154
disorder n/a 1193 1194
disorder n/a 1246 1254
low_complexity n/a 1315 1333
disorder n/a 1325 1329
disorder n/a 1331 1344
disorder n/a 1375 1376
disorder n/a 1392 1538
low_complexity n/a 1425 1432
low_complexity n/a 1475 1491
low_complexity n/a 1484 1497
low_complexity n/a 1498 1512
low_complexity n/a 1518 1528
low_complexity n/a 1536 1552
disorder n/a 1540 1547

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A4HX31. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSLTTAFPFH AYVGDLRTRT VHERKSGVSL SLMTSEDMAR LAFVEVRVRC
50
51
GQEDRLAPWT PALRRDGTHA TFYDTRMGNF DARTFPPQAC STCCSTLNSK
100
101
YGNERCQGHY GYISMPRRYP NDPNRSQERL SVINPHLAQE VEQLLQAECF
150
151
FCHRFRVPEF DVMRYQQALR LVDCGLIGEA LRFLDMVANA HGQDMRSRRR
200
201
RDANETVIND IPLMLDHVDK LLRRRGVAAP PLPEVASGEA GAHGDAQGDA
250
251
GAAGALAHVD GSDDGFRKPV LDVRNEICKQ ALRSFREFGN VCSHCQGISP
300
301
RITTKNGHLF FFFNKKNADF NVANGGVTTS QLREWEEMNR RQGRSHTYFR
350
351
TSWVREHIKQ LCQRESAILA ALFPHLGETT LHMPYACSLP SMYYYKVFFV
400
401
DKLLVPPLPL RLSSGVQISE SGGIIPDAGT RALSDVLEFV EQIEAYYVLA
450
451
NNSTPERNLV STAQEVAQEH NLRNLQAKVT EVYTDVLEGF AKKEGLFRMH
500
501
MMGKRVNQAC RSVISPDYLV EPNEVLLPRP FARALTFPEL VSSYSPARMV
550
551
FLKRCVMNGP DVYPGATHLE IGLPSGETRF VDLHVPELIR RQHAMKYFAM
600
601
AQNGSLTVHR HILDGDHLIF NRQPTLHKVS MMAYRAKVLS GLKTLRFHYV
650
651
NGSSYNADFD GDEMNIHVVQ SLEAKAELEC LMDANLNYLV PTSGKPIRGF
700
701
IQDHVVAGVL LTLRDNFLPH HTFVQFVYNG IAPYMQKQGK PLSAHATLTG
750
751
LIPMPAVLKP RPLWTGKQLI SVIVHYVTGV VESRGGAPRS NGVSMHGTSL
800
801
IQPSTYTTTD PHTGELVTAS RKCMEDDHVQ FFESELITGI LCKNQLGSSN
850
851
LSVVHVIHEI YGPHMVGELF GALGRVLSMS LQREGFSIGM DDMMLLQEER
900
901
RTALLRELDS APLSLPDDEA RVMPVIMGMA TSLQKEFVPG RMLRPFPYNQ
950
951
LLTMTMSGAK GSNTNAIQMS LGLGQQLFDG RRVKRMNSGK TLPPFFVAEK
1000
1001
RARSLGYAIG RFTSGIRPAE YTFHAMAGRD GLIDTAVKTS RSGHLQRCLV
1050
1051
KGLESLVVQW DHSVRDANGS VIQFLYGGDG LDPMRTSSLQ AWEVVKDNCI
1100
1101
DLGRKMNVNT GVVTGEEEAE EAASRNSQGK RERAHEAAAA MRAAQRALLE
1150
1151
AEAQRDPLPA HYKASLDMYL ETKAQYPLFK KVSQVARWTK NGVLNEKLRE
1200
1201
KREESIRYYR DVMTELTTRR RVRAYCDAGE PVGLLAAQAA GEPSTQMTLN
1250
1251
TFHSAGSTVT HVTEGIPRLR ELLIYASVQK VAIVVPVEKA TEVDEEAISR
1300
1301
ILQAGVATRL TDCMARVPAA VTATADDGAA ARAQTTPGYH YRVTRSAEGT
1350
1351
QVTVALLFSK ALLMQKQHAM CMSRAEHLQS FTQTLKNFAR QVVTALRGRS
1400
1401
KDEREGAGGP LRGTTQDPSS QMDDGGAAAG GGMSDNEDDM DERSTQMNTP
1450
1451
ALGATSVPSV AGSELGRDDM IPERDDNGGS SGSDEDDYDE EAVDAADGSR
1500
1501
RRKGGNGSSP PRKKSRAEEG DNEEDDEDVN GLFWKSSSNG GTSSEAAAAA
1550
1551
SGKVSYDCFP TVCVMYGSKK YRVEIAPLLR EAATRDGVVP LPEDLFVVNV
1600
1601
SIQTSDQVVT VIPDVLESAL AQQTFPSWLT QFDSVTYTRK AEDPTSGEMV
1650
1651
FQGSSATIRS VTAFLALFTV RARAIKVQKA RSTDIRDMCT SFGVESGYKA
1700
1701
LFDELEKLFK RYSVDYHHLT LIADAATHRG VWENYNFTGV ISHSASPLFQ
1750
1751
MTFASSKRFL HTALTRGVGD ELNSISSAIM VGERPRVGTA LVKVGQDPQI
1800
1801
LRDVIEKNFA                                            
1810
 

Show the unformatted sequence.

Checksums:
CRC64:A929500D3A9E8380
MD5:38e3f5c5fb126b8a2ba4a47952f65071

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;