Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A4HYJ9_LEIIN (A4HYJ9)

Summary

This is the summary of UniProt entry A4HYJ9_LEIIN (A4HYJ9).

Description: DNA_repair_protein_BRCA2_-_putative {ECO:0000313|EMBL:CAC9484009.1}
Source organism: Leishmania infantum (NCBI taxonomy ID 5671)
Length: 1165 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 31 202
Pfam BRCA2 109 132
coiled_coil n/a 159 179
low_complexity n/a 180 197
disorder n/a 209 220
low_complexity n/a 211 226
disorder n/a 223 236
disorder n/a 239 245
disorder n/a 271 281
disorder n/a 283 285
low_complexity n/a 313 326
Pfam BRCA-2_OB1 424 535
low_complexity n/a 538 554
disorder n/a 571 589
disorder n/a 612 616
disorder n/a 618 619
low_complexity n/a 861 869
disorder n/a 866 868
disorder n/a 885 886
low_complexity n/a 891 906
low_complexity n/a 931 947
disorder n/a 947 952
disorder n/a 958 959
disorder n/a 964 965

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A4HYJ9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKTIACPHCT FINPPSKVKC GVCLRLLRKR ERTVADASPA TANRGRKGTP
50
51
SPSSTPTEHD SPATGSSQVR CDTTKSSMPL ATPKSGTVAS AQAVQPPDVE
100
101
AMAAAPPLVP TLFSTASGKP VTVRRESLQK VAERLGDLAA PDMEARVPTL
150
151
FETGRGKAVT VQKRSLDKAE ASMDSLEADG APSTSAPALS ATTGGAAVRV
200
201
PAVPLQAPAE RLRLKSLSDK DDTSDTAAVR SIGAPRQTAR AEALSRGLTT
250
251
STSECGLRAL ALHVIGGQRR GFVPPQQRPS AQPLAKLTHA VPLVKTSALT
300
301
ILRFNPDACT CRSITPSPSL SSITSLMFSF KGSDCGKVLA ALLGVSGAES
350
351
VQPLHWHAML LKLGASPKHC TINWCRHALV SAMARAHFMT KVPSGALPSA
400
401
FSPVTVLLCV MQMYNAEMVN GERPALRKMV EGDISSASLV VLYMSSVSEE
450
451
RSSPHMRIVT LSDGIYHLKV TCDVPLSNLI REGVLKPGQR MAVCGAKSLL
500
501
HRQCAPTECE EQVVLSINYN CVRAVAQQTP LGVCHGEPLP LPLSLVHPLG
550
551
GLVPAIEGVV ARTLPSFFVS EEATETPGTH DGARQARNRV FKTVRNAHAQ
600
601
LQVSDRLRRE AEAWADGEAA QSKPLSRVTS LLIVKDNAEA LVQQWETVDE
650
651
RVLLADDDGG ASLPVEGSWV TLYAVNPAKS RTAAAPFPRA KLFFSSRQLH
700
701
YVPSKNPLQH LRRIWMAATD NKSTAGVGDV ADVCGLYMGS HRNEQGTFAL
750
751
LLLRNDTYAL LQVPVPSAGR ALSLPLPATE RLSLVVLNAT FLTGEDPVAG
800
801
SDCCRLFANE YTAVLQRSTQ ANLKEALETA AQLRGLVDAA PQKYAARKAE
850
851
VFRCIDEGEP SGGLGLGSST ALTIRDGQGV PEVPLNVWRD APLASPSAAA
900
901
TSLVPAQRYG RLPYYLRQDN ERAIAGKLTG VLLPSAALPT PAVPTAVQGP
950
951
YSATTIHPGV REPLVQPANS VAGARSRHYG NIADLMFLFD PRLNRRAWHP
1000
1001
LTDPLQVTSS EVVRHGECFK RAQLCWRLSA DSADDMTCRV EESSILGTVL
1050
1051
ESVCPLQELC SVIADERHID VSLARSERLV QWRRQDSLSV WWRFFTDSRA
1100
1101
LASPADLDGA SSEHLWWLPA EWTAAMRTVS AKLQAAFFYF SLSGEVLRHV
1150
1151
RLISDCCSVA ELPCD                                      
1165
 

Show the unformatted sequence.

Checksums:
CRC64:F96A77CE08857976
MD5:9d9042f3b3bc4fa210b801121ebeb0b2

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;