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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A4I6B6_LEIIN (A4I6B6)

Summary

This is the summary of UniProt entry A4I6B6_LEIIN (A4I6B6).

Description: Bifunctional lysine-specific demethylase and histidyl-hydroxylase {ECO:0000256|RuleBase:RU366061}
Source organism: Leishmania infantum (NCBI taxonomy ID 5671)
Length: 507 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 27
disorder n/a 32 38
Pfam Cupin_4 122 382
disorder n/a 310 311
disorder n/a 315 319
disorder n/a 327 332
coiled_coil n/a 330 350
disorder n/a 334 345
disorder n/a 383 393
disorder n/a 505 507

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A4I6B6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTKAASLKKG SGDKRPREAS LEVTAGKPKV ETAAVLPKAS HGSQAHPNFF
50
51
SWLLKTSRGE FFRKYFERKH LVASHGSGEY FASGLPGVVP PVNWSTERML
100
101
DHVKTHPSRY GADLDVVKFD PKLKRRVSFR TKGLVDAAEL ETCMKGGWSV
150
151
RFLRPNEFIE SNSAFIGCME KEFNCYCGVN SYWTPANSQG FAPHYDDVDV
200
201
FLLQLEGEKL WCLYDPPEDV DVLARHSSED YAPELFPTPK HTITLKAGDV
250
251
LYMPRGTVHQ GKTTLKTHSL HITFSANQMN SWADFMSRAA QYTVEKLAAN
300
301
KMEWRRALPR SMPQVVGEVN NPVFRDTHGL AALSEKQQEH RANLQTKVRE
350
351
MVAELTLLLT DEGNMDMCAD VYAKDTIRKL QPPSRTYSGA APASTRLSHA
400
401
SRVRLISRNC MRLLLNVPGE ARVYHTGRNS TVCLGGELGE LRFEADFAPA
450
451
IATLLSSYPK TMPVSALPFP GFDDSDDVAE NQLLLVETLR DAGLLHVGSS
500
501
ANGNAPS                                               
507
 

Show the unformatted sequence.

Checksums:
CRC64:A3ABC0F82ADE781A
MD5:545cee2b21d7e85722e7499d27bfbd19

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;