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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A4QNU3_DANRE (A4QNU3)

Summary

This is the summary of UniProt entry A4QNU3_DANRE (A4QNU3).

Description: Claudin {ECO:0000256|RuleBase:RU060637}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 256 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam PMP22_Claudin 4 173
transmembrane n/a 7 26
transmembrane n/a 77 102
low_complexity n/a 88 102
transmembrane n/a 123 143
transmembrane n/a 155 176
disorder n/a 185 200
disorder n/a 203 220
disorder n/a 224 228
disorder n/a 230 231
disorder n/a 244 256

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A4QNU3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSNSCRLLCG FLMSFVGWIG IIIATSTNDW VLSCTYGSHS CRNMDDLETK
50
51
GLWTECVIST ALYHCIPLNQ VRRIPAYIQA CRVLMVSASL LGLPALALLL
100
101
LAMPCVKVSQ ETEGTKHRRA VQGGLIILVI SLCGMVSTVW FPIGKLDGLM
150
151
SFGFSLYAGW VGSALCFFAG SVMVCCSKDH SPSENPESRH YYSNPDGVTS
200
201
TGPSENPETR YYYSNHDGVT SSGTSENQET RFYYSNHDGV TSYGPAKNSH
250
251
AKSEHV                                                
256
 

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Checksums:
CRC64:7512C0D2C1669AA4
MD5:dbc4ec2d34633700e62af4d6e5fcd431

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;