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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A4QPA0_DANRE (A4QPA0)

Summary

This is the summary of UniProt entry A4QPA0_DANRE (A4QPA0).

Description: Malic enzyme {ECO:0000256|RuleBase:RU003426}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 603 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 29
Pfam malic 113 294
low_complexity n/a 191 202
Pfam Malic_M 304 556
disorder n/a 385 390
disorder n/a 392 393
low_complexity n/a 409 419

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A4QPA0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNSLSGKSVL TLCRAFSSPL LLPPAMVGAV RVCHTGVNSK GTVFTRKRGY
50
51
DITRNPHLNK GMAFTLEERL QLGIHGLLPP CFLSQDVQVL RVMKSYETRS
100
101
NPLDKYILLM TLQDRNEKLF YRVLTSDIEE FMPIVYTPTV GLACQQYGLA
150
151
FRRPRGLFIT IHDKGHIATM LNSWPEEDIK AIVVTDGERI LGLGDLGGYG
200
201
MGIPVGKLAL YTACGGVPPQ QCLPVLLDVG TDNQTLLDDP LYIGLKHKRV
250
251
RGKEYDDLID EFMQAVTDKY GMNCLIQFED FANSNAFRIL NKYRNRYCTF
300
301
NDDIQGTASV AVAGILAALK ITKNKLSDHK FVFQGAGEAA LGIAHLLIMA
350
351
MAKEGIPHAE AAQRIWMVDS KGLIVKGRSH LNHEKEEFAH DHPHIKTLEE
400
401
VVETIKPTAI IGVAAIGGAF TEKIIKNMAA NNERPIIFAL SNPTSKAECT
450
451
AEQCYTLTEG RGIFASGSPF KKVTLADGRS FYPGQGNNAY VFPGVALGVI
500
501
ACGVRHISDD IFLTTAEAIS EMVTEEHLAE GRLYPPLKTI REVSFKIAVK
550
551
IVDHAYKQGI ASWYPEPKDK EAFILSHVYN SDYDSFTLDS YSWPKDAMKV
600
601
QNV                                                   
603
 

Show the unformatted sequence.

Checksums:
CRC64:4EC264423FCE49CE
MD5:eb263ea2582ecefa02a4c05094283340

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;